Studying T-Cell Exhaustion in Brain Metastases

We talk with Dr. William Hudson about his work at Emory University, where he combines single cell immune profiling and spatial analysis to inform development of immunotherapies for brain cancer.

The conversation continues in Part 2 of our chat with Todd and Maigan Brusko at the University of Florida, Gainesville, as they go even further into their research on Type 1 Diabetes.

In this episode, we're kicking off a fascinating two-part discussion with Todd and Maigan Brusko at the University of Florida, Gainesville, about their research on Type 1 Diabetes.

We sit down with DO/PhD candidate Dianna Nguyen, a member of Tom Cunningham’s lab, and former core lab manager at the University of North Texas Health Science Center, Nicky Hales. Hear how one spatial transcriptomics experiment can change the direction of a research project and open up new sets of questions and paths of further study.Take scalable single cell analysis from your wish list to the bench with our September 2021 Chromium X Special Offerhttps://pages.10xgenomics.com/2021-09-instrument-reagent-promo.htmlDon't delay! Get your order in by September 24th 2021.

In this episode, we talk about single cell analysis of the immune response in diverse disease types, from cancer to COVID-19, with researchers at the University of Pittsburgh: Tony Cillo, PhD, Postdoctoral Associate in the Vignali Lab in the Department of Immunology and Hillman Cancer Center, and Bob Lafyatis, MD, Professor of Medicine in the Division of Rheumatology and Clinical Immunology.Link mentioned in the episode: 10xgenomics.com/gem6

We talk with Mathieu Lupien, PhD, a senior scientist at the Princess Margaret Cancer Centre and associate professor at the University of Toronto in Canada. Hear how studying chromatin state and transcription in individual cells has opened up a new area of research in gene regulation and cancer progression.

We talk with Olivia Koues, PhD, managing director of the Advanced Genomics Core at the University of Michigan, about the role of a 10x Genomics Certified Service Provider in supporting your experiments.

And you thought you could only resolve cellular heterogeneity in fresh frozen tissue. Time to bring out the FFPE blocks!

You may be familiar with how single cells get isolated or tissue gets sliced, but do you know how to mine the most important results in all that data? We describe tools developed by 10x Genomics as well as a few from third parties that can further extend your analysis, such as Seurat, Azimuth and Monacle.

Maybe you're asking, "Who are these people? Why are they hosting a podcast?" Find out the answers to these questions and more in this first episode of the Cell Intel podcast from 10x Genomics.