How To Clear Brain Fog (Simple Methods) : 1332

If you feel like your brain's stuck in first gear, losing focus, forgetting simple things, feeling mentally sluggish—you’re not alone. I lived with brain fog for 15 years while building companies in Silicon Valley, and no productivity hack or double espresso fixed it. In this episode, I’ll show you how to clear brain fog at the cellular level by restoring mitochondrial energy, ditching brain-damaging foods, optimizing sleep, and upgrading your nutrition. These are the exact science-backed steps that got me back to feeling sharp, focused, and fully me. Let’s turn your brain back on.Chapters:0:00 – Introduction0:49 – The Root Cause of Brain Fog1:26 – What Most People Get Wrong2:20 – How to Fix Your Mitochondria2:57 – Food: Fuel or Poison4:48 – The 4 Brain Poisons Killing Your Focus5:20 – Exercise for Brain Energy (Not Burnout)7:55 – Brain Fog Supplements That WorkBrain fog supplement: https://shopsuppgradelabs.com/products/brain-101, use code DAVE15 Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Confidence is biology you can hack. In this episode, you’ll see how confidence builds inside your brain, rewires through neuroplasticity, and connects directly to mitochondria, metabolism, and human performance. You’ll get tools that reprogram fear, regulate your nervous system, and turn stress into fuel so you build radical confidence that lasts. Listen to this classic with host Dave Asprey as he talks with entrepreneur, author, and Women of Impact founder Lisa Bilyeu. Lisa went from a stay-at-home “supporting role” to co-founding Quest Nutrition, scaling it into a billion-dollar company, and running a global media empire. She brings years of lived experience and applied mindset training, making her one of the most authentic voices on confidence, resilience, and leadership in the biohacking world. You’ll learn how to: • Hack confidence with the same strategies you use for sleep optimization, fasting, and cold therapy • Spot biological triggers behind fear, self-doubt, and procrastination • Use repetition and mindset tools to upgrade brain optimization and neuroplasticity • Turn stress hormones into growth signals for longevity and functional medicine practices • Reframe trauma and setbacks as power for resilience and high performance • Support courage and focus with nootropics, ketosis, supplements, and Danger Coffee This episode shows you how to treat confidence as a trainable skill, not a personality trait. If you want smarter not harder strategies to master your biology, expand your impact, and live with unshakable resilience, you’ll find them here. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Lisa Bilyeu, Radical Confidence, Quest Nutrition, Women of Impact, confidence training, resilience biohacking, mindset reprogramming, courage hacking, fear rewiring, entrepreneurial mindset, human performance, brain optimization, neuroplasticity tools, mitochondria and confidence, trauma resilience, emotional regulation, nootropics for confidence, stress as fuel, leadership confidence, Human Upgrade podcast Thank you to our sponsors!  EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Resources:  • Lisa’s Website: https://lisabilyeu.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 0:38 – Intro 2:38 – From Housewife to Entrepreneur 17:52 – Building Impact Theory 27:56 – Radical Confidence 39:14 – The No BS Game 44:45 – Finding Purpose 55:34 – Inner Critic & Competence 1:01:10 – Becoming Your Own Hero 1:08:32 – Boundaries & Relationships 1:09:52 – Conclusion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you’ve ever cringed at the sound of your own voice or struggled to hold attention in a room, this episode will change the way you speak and how others respond to you. You’ll discover how vocal tone, breath, and emotion act as biological levers you can train to improve your health, extend your longevity, and build magnetic charisma. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Roger Love, the celebrity voice coach who trained Bradley Cooper, Tony Robbins, Selena Gomez, and Brendon Burchard. Roger has spent decades teaching actors, executives, and performers how to master their voice to create influence and impact. In this conversation, he shares the science behind vocal tone and the emotional cues hidden in your breath. You’ll hear why most people speak from the wrong part of the body and how that drains power from every interaction. You’ll learn how digital habits dull your voice, which techniques make you sound more confident and trustworthy, and why sound can heal the nervous system. Dave and Roger also explore how voice training supports your biology, boosts emotional control, and protects your performance as you age.  This episode gives you tools to speak with more authority, connect on a deeper level, and improve your health through one of your most underused systems: your voice. If you want to lead, perform, persuade, or simply feel heard, this conversation shows you how to upgrade the way you sound—and how you feel when you speak. You’ll learn: • Why most people speak from the wrong part of their body • How your voice shapes the way others feel about you • The link between vocal tone, breathing, and nervous system health • How to sound more confident, persuasive, and emotionally resonant • Why digital habits are weakening your communication • How to train your voice as a powerful analog biohack for longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Roger Love, voice coach, Bradley Cooper, vocal tone training, voice confidence, charisma training, sound healing, biohacking voice, emotional resonance, public speaking, vocal mastery, breathwork, mitochondria and voice, analog biohacking, vocal optimization, high performance communication, voice training for health, Tony Robbins voice, Human Upgrade podcast Thank you to our sponsors!  BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. STEMREGEN | Go to https://stemregen.co/dave25 and use code DAVE25 for 25% off your order. Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order.  **If you're interested in Voice Training, go to www.rogerlove.com/dave and use code DAVE for $50 off** Resources:  • Roger’s Website: www.rogerlove.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer• 1:30 – Intro• 1:48 – Meet Roger Love• 3:22 – Nature vs. Nurture• 5:46 – Speaking vs. Singing• 7:02 – Breathing & Voice Health• 13:35 – Voice & Attractiveness• 19:13 – Stuttering & Vocal Disorders• 24:51 – Emotional Speaking• 29:04 – Mastery & Finding Your Voice• 39:55 – Voice & Technology• 49:20 – Becoming AI-Proof• 56:29 – Emotion & Sound• 1:04:30 – Stage Fright & Tone Deafness• 1:08:00 – Voice Training TipsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you’ve ever felt crushed by stress or trapped by fear, this episode gives you the science and strategies to break free. You’ll learn how Olympic-level coaching can rewire your brain for resilience, unlock peak human performance, and extend your longevity through proven biohacking tools. Watch the video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jim Murphy, a former professional baseball player turned Olympic coach and now bestselling author of Inner Excellence. Jim has spent decades training world-class athletes and high performers to master their mindset, expand neuroplasticity, and build the courage to thrive under pressure. His work blends psychology, functional medicine, and elite coaching to help people overcome fear, reframe failure, and step into their highest potential. Together, they explore the inner game of stress mastery: why fear lives in your mitochondria, how shame and guilt sabotage performance, and how to turn setbacks into resilience. They also discuss supplements that improve metabolism, why childlike wonder fuels longevity, and how to use practical biohacking to cultivate courage. This is essential listening for anyone serious about hacking fear, upgrading resilience, and living the smarter not harder way. Whether you’re chasing athletic greatness, leading at the highest level, or just seeking more freedom in daily life, these strategies show you how to unlock love over fear and achieve lasting longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Keywords: inner excellence, Jim Murphy, Olympic coach, fear hacking, stress mastery, resilience training, courage mindset, shame vs guilt, brain optimization, neuroplasticity, mitochondria stress, childlike wonder, longevity habits, emotional resilience, high performance, mindset coaching, presence training, love over fear, functional medicine, stress recovery, AJ Brown, AJ Brown book, Eagles football player book, NFL sidelines book  Thank you to our sponsors!  LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources:  • Jim’s Website: https://innerexcellence.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:30 — Intro3:10 — Subconscious Mind and Fear4:36 — Purpose Beyond Results6:38 — Writing Inner Excellence10:16 — Redefining Mental Toughness14:11 — Guilt and Shame18:24 — Embracing Fear and Challenge23:50 — Teaching Kids and Modeling Behavior31:44 — Childhood Programming and Performance45:59 — Living Fully, Ready to Die??:?? — Maintaining Childlike WonderSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sabotaging your hormones. Want results? Start here.Chapters:0:00 – Introduction1:40 – The Lie About Aging and Testosterone2:49 – What’s Desatroying Your Testosterone Daily3:42 – How Your Cells Actually Make Testosterone4:58 – Why Diet is Step One (and What to Eat)7:08 – The Most Underrated T Booster8:38 – The Truth About Light and Hormones14:40 – How to Fix ItGet Your Oral Testosterone Here: http://www.LiveThrive.co/asprey Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You’ll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You’ll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion’s mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion’s mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20’ for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am…  • Paul Stamets’ Website: https://hostdefense.com/ Thank you to our sponsors!  • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources:  • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion’s Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with neuroscientist and physician Dr. Tony Nader, the global leader of the Transcendental Meditation movement. With an MD and PhD from MIT and Harvard, Dr. Nader bridges hard science with ancient wisdom, showing how TM measurably changes brainwaves, boosts mitochondria, and even slows biological aging. His research connects meditation to reduced stress, faster reaction time, and improved memory, giving listeners cutting-edge tools for smarter not harder living. You’ll Learn: • How Transcendental Meditation induces high-coherence alpha brain states that improve clarity, focus, and resilience • Why TM increases blood flow to the prefrontal cortex and supports memory, decision-making, and creativity • How meditation measurably reduces biological age by 5–10 years through stress reduction and physiological balance • Why reaction time and situational awareness improve immediately after meditation — even used by fighter pilots • How TM differs from mindfulness or concentration practices at the brainwave level (alpha vs. theta vs. gamma) Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Transcendental Meditation benefits, Tony Nader MIT neuroscientist, TM brainwaves alpha coherence, Meditation and neuroplasticity, Default mode network meditation, Meditation and mitochondria, TM and biological age, Consciousness and quantum field theory, Meditation vs psychedelics, Meditation and intuition training, Meditation and dopamine, TM reaction time studies, Hippocampus meditation memory, TM and functional medicine, Meditation and metabolism, Meditation and PTSD recovery, TM for sleep optimization, Meditation and fasting stack, TM and human performance, Meditation and longevity research Thank you to our sponsors!  Business of Biohacking Summit | Apply to The Business of Biohacking Summit https://businessofbiohacking.com/.  fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources:  • Tony’s Website: https://drtonynader.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:47 — Intro 2:57 — Transcendental Meditation 3:56 — States of Consciousness 10:16 — Brainwaves & Practice 18:35 — Science Bias 38:07 — Mind & Reality 50:32 — Psychedelics & TM 54:29 — Brain & Body Effects 59:31 — Daily Practice 1:02:43 — Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Suzanne O’Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it’s too late. Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You’ll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. You’ll Learn: • Why fear of death silently undermines health, performance, and human potential • How forgiveness and gratitude rewire neuroplasticity and boost brain optimization • What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm • How unresolved trauma shows up as physical pain and disease at the end of life Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care Thank you to our sponsors!  ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino.  Resources:  • Suzanne’s Website: https://suzannebobrien.com/ • Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com• Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:05 — Introduction 03:13 — End-of-Life Choices 09:50 — Forgiveness & Suffering 15:46 — Advice to Younger Self 20:00 — What Makes a Good Death 23:00 — Hospice Stories & Mystical Experiences 33:05 — The Good Death Defined 41:01 — Meaning & Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You’ll learn how to rethink daily eating so it fuels energy, resilience, and long-term health instead of quietly sabotaging it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Max Lugavere, health journalist, filmmaker, and bestselling author of Genius Foodsand The Genius Kitchen. Max is one of the most trusted voices in nutrition and functional medicine, translating complex science into practical tools you can use right now. His work has been featured on The Today Show, PBS, and across global media for helping people reclaim health through smarter food and lifestyle choices. In this re-run, Dave and Max break down the real impact of sugar, salt, and food processing on your brain and body. They explore how cooking methods change health outcomes, when fasting and ketosis become powerful tools, and why supplements, nootropics, and trace minerals fill gaps in the modern diet. They also tackle controversial topics like carnivore diets, cold therapy, and whether “healthy” plant-based foods are truly supporting resilience—or quietly eroding it. You’ll Learn: • The biggest nutrition myths that silently damage health and performance • How sugar can act as both poison and fuel depending on context • Why cooking methods make the difference between nourishment and toxicity • The overlooked role of minerals, supplements, and culinary literacy • How nootropics, cold therapy, and sleep optimization reset your brain • Why some “health foods” accelerate aging instead of protecting you • The truth about carnivore diets, industrial farming, and sustainability • When fasting, ketosis, and carb cycling create optimal results This episode gives you a science-backed blueprint to hack your nutrition, sharpen your brain, and extend your longevity with foods that truly support your biology. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer’s risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources:  • Max’s Website: https://www.maxlugavere.com/ • Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:30 — Introduction 1:51 — Resilience & Stress 2:41 — Food Philosophy 6:20 — Sugar & Metabolism 11:21 — Fructose & Flexibility 21:57 — Big Food & Morality 24:51 — Meat & Sustainability 26:30 — Cooking at Home 28:34 — Salt & Minerals 30:07 — Dietitians & Industry 32:45 — Intuitive Eating 41:13 — Cooking Risks 45:26 — Fish & Contaminants 49:16 — Lectins & Sensitivities 52:22 — Herbs & Spices 54:59 — Recipes & Highlights 58:17 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think broccoli is a superfood, but the reality is more nuanced. In this episode of The Human Upgrade, Host Dave Asprey explores the good and bad of broccoli—why adult broccoli can block thyroid function and cause gut issues, while broccoli seeds deliver sulforaphane, the powerful compound that activates all three of your body’s detox pathways. You’ll learn how sulforaphane protects against glyphosate, repairs leaky gut, and upgrades mitochondria, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave is joined by two Johns Hopkins–trained researchers whose expertise in biohacking, biochemistry, and functional medicine makes them trusted leaders in the field. Together they reveal how sulforaphane, berberine, curcumin, and alpha-lipoic acid outperform bulk vegetables and even rival GLP-1 weight loss drugs—delivering natural ways to improve metabolism, regulate dopamine, and protect the brain. Their research shows how targeted supplements can boost neuroplasticity, brain optimization, and human performance without the side effects of pharmaceuticals. Dave and his guests break down why bulk vegetables don’t deliver enough beneficial compounds, how to hack plant toxins for maximum benefit, and why supplement stacks often outperform carnivore, vegan, or high-vegetable diets for long-term health. You’ll discover how biohacking tools like fasting, ketosis, nootropics, cold therapy, and sleep optimization amplify these compounds for smarter not harder living. You’ll Learn: • Why adult broccoli can disrupt thyroid function while broccoli seeds fuel detox and longevity • How sulforaphane, berberine, curcumin, and alpha-lipoic acid support metabolism and mitochondria • Why natural compounds can rival GLP-1 drugs for weight loss and energy regulation • The connection between glyphosate, leaky gut, inflammation, and brain fog • How to stack supplements with fasting, ketosis, and cold therapy for brain optimization • Why functional medicine and biohacking provide better long-term solutions than fad diets • The smarter not harder way to extract benefits from plants without the toxic load This episode is essential for anyone serious about biohacking, upgrading metabolism, extending longevity, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: sulforaphane supplements, broccoli seed extract, detox pathways phase 1 2 3, NRF2 activation, glyphosate gut health, leaky gut repair biohacking, thyroid blockers broccoli, DIM I3C compounds, functional medicine detox, Johns Hopkins biohacking research, berberine metabolism, alpha lipoic acid mitochondria, curcumin weight loss, GLP-1 natural alternatives, dopamine metabolism regulation, neuroplasticity supplements, fasting and sulforaphane, ketosis and detox synergy, smarter not harder supplements, Dave Asprey broccoli Mara Labs Website: https://mara-labs.com/Dave for 28% off!Resources: -Mara Labs Website: https://mara-labs.com/Davefor 28% off!-BrocElite link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123-GLPerfect link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123Thank you to our sponsors!  EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources:  • Mara Labs Website: NEED TO INSERT CODE • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 01:49 — Broccoli Benefits & Risks 09:24 — Plant Toxins & Modern Diet 12:56 — Mold Detox Experiences 18:30 — Mycotoxins, Glyphosate & Gut Health 26:20 — Metabolic Syndrome & Endotoxins 35:44 — Timing Sulforaphane for Glyphosate Protection 39:35 — Weight Loss & GL Perfect 49:19 — Personalization & Supplement Stacking 55:10 — Sleep, Ketosis & Berberine 58:30 — Alpha Lipoic Acid + Berberine Synergy 1:01:00 — Natural Alternatives to GLP-1 Drugs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.