
Dr. Nichola Conlon was working in early-phase drug development, watching molecules that worked get shelved because nobody could patent them, when her boss told her that if she cared that much she should go start her own company. She did. Here she takes apart most of what the longevity market has sold you about NAD: why an NAD IV makes zero sense the moment you look at the chemistry, what a human trial found it actually triggers in the body, why oral NAD pills are degraded long before the bottle reaches your door, and why you get none of it from food, whatever the Instagram lists claim. She lays out the two real reasons NAD falls with age, the fasting windows that switch the key enzyme back on, and what her peer-reviewed crossover trial measured in people aged 20 to 80. She also says plainly where she breaks with David Sinclair. Plus the menopause finding that explains why so many women say they aged a decade overnight.
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Chapters: 00:00 - Intro 01:18 - From Cancer Drug Development to Longevity Research 04:31 - What NAD Is & Why It Matters 06:55 - Can You Actually Measure NAD Levels? 08:28 - Why NAD Declines With Age & Inflammation 12:04 - Why Nichola Says NAD IVs Don’t Make Sense 15:04 - NAD, Fertility & Women’s Health 17:54 - NMN vs. NR vs. Nicotinamide 18:59 - Does NAD Increase or Decrease Cancer Risk? 21:21 - How Much NAD Should You Actually Take? 23:53 - The Myth of Getting NAD From Food 27:16 - Fasting, Exercise & Naturally Boosting NAD 29:20 - NAD, Alzheimer’s, Parkinson’s, Metabolic Health & Menopause 31:35 - Why Nuchido Took a Different Approach 33:56 - The Human Clinical Trial Behind the Product 38:11 - Reformulating the Product & Retesting It 40:06 - Do You Need to Cycle NAD Supplements? 41:04 - Hormesis, Modern Life & Cellular Repair 43:21 - David Sinclair, NMN & the NAD Debate 47:24 - Epigenetic Reprogramming & Reversing Cellular Aging 51:43 - What Nichola Noticed After Taking Nicotinamide 53:24 - Biological Age & Why It Matters 55:32 - Fertility, Ovarian Aging & Menopause 59:36 - What’s Next: Senescent Cells & “Zombie Cells”
01:02:59 - Final Thoughts & Outro 🔔 Hit that subscribe button for exclusive access to thought-provoking podcasts, self-growth tips, inspiring guidance, empowerment for bold spirits, and more! https://www.youtube.com/@Biohack-it/?sub_confirmation=1
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👉 Season One https://www.youtube.com/playlist?list=PLQWTIuStNqibK2-K-T3GfnIxdLlK_KXMD
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✅ About Biohack-it.
Welcome to Biohack-it! Immerse yourself in a world of authenticity, empowerment, and innovation. Biohack-it, led by Iman Hasan, is a transformational journey of personal development and self-discovery. Join us to nurture bold spirits, ignite meaningful conversations, and celebrate your true self. We're not just storytellers; we're architects for change.
Biohack-it isn't your typical wellness podcast. It's a beacon for the bold and curious, craving authenticity. Discover conversations that challenge the status quo and empower your deepest self. With Iman Hasan's guidance, each episode becomes a chapter in your self-discovery journey.
🔔 Subscribe & stay tuned for exclusive content on captivating podcasts, self-discovery tips, nurturing bold spirits, insightful guidance, and more! https://www.youtube.com/@Biohack-it/?sub_confirmation=1
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⚠️ DISCLAIMER: The content shared on Biohack-it is for informational purposes only. It's not intended as medical advice, diagnosis, or treatment. Always consult with a professional for health-related inquiries.
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