Will Crypto ETFs Transform the Market? Expert Insights from Matt Hougan, Bitwise CIO

In today’s episode with cypherpunk and artist Gus Grillasca, we explore the intricate crossroads of cryptocurrency and global economics. From the propaganda of inflation to Bitcoin Ordinals and the NFT controversy, this episode challenges conventional narratives and opens up new perspectives. Hear Gus' insights on navigating the Ethereum ecosystem, the financialization of Bitcoin, and privacy coins in the digital age.We also talk about the evolving role of crypto in Latin America, reflect on the surprising dynamics of meme coins, and uncover gaps in financial literacy that could shape the next chapter of blockchain adoption. Whether you’re captivated by the promise of stablecoins, intrigued by NFT permanence, or pondering crypto’s place in an unstable world, this episode offers thought-provoking insights and artistic freedom at its core.INFLARE: https://scarce.city/goods/inflare Fierro Viejo: https://superrare.com/artwork/eth/0xb932a70A57673d89f4acfFBE830E8ed7f75Fb9e0/34374 Chapters:00:00 Defiant Intro00:10 Inflation is bankers’ propaganda00:50 Introduction to Gus Grillasca01:38 Gus’ Journey into blockchain02:35 Banking challenges for travelors04:44 Rare Pepes, Ethereum NFTs, and Bitcoin Ordinals07:44 Changing views on the Ethereum ecosystem09:04 Bitcoin Ordinals, memes, and the NFT Controversy10:30 Bitcoin Ordinals and NFT permanence14:53 The controversy around updates to the Bitcoin protocol16:28 “INFLARE” and The Space by Art of Freedom17:25 Inflation as a monetary phenomenon21:06 Global inflation, purchasing power, and the role of crypto in an unstable world25:37 Is the financialization of Bitcoin good or bad for crypto?27:25 Bitcoin Reserve and the Digital Asset Stockpile30:36 Thoughts on $TRUMP and other meme coins34:45 Changing expectations of investing in NFT38:18 Crypto’s role in Latin America45:35 “Fierro Viejo,” NFTs and intellectual property50:00 A gap in financial literacy 53:18 Ethereum’s changing roadmap57:25 Privacy coins59:40 The need for privacy in the digital age01:03:05 Stablecoins, financial products, and exciting prospects in crypto 01:05:56 Final Thoughts

Are crypto ETFs set to reshape the investing landscape? Join us on The Defiant as we dive deep into the future of crypto assets, the evolving regulatory environment, and the rise of index-based investing. Matt Hougan, CIO of Bitwise, shares his expert insights on what these changes mean for investors and how crypto ETFs could revolutionize access to digital assets. Chapters:00:00 The Defiant Intro00:10 Why tariffs could be bullish for Bitcoin 00:41 Intro to Matt Hougan, CIO of Bitwise01:35 The impact of U.S. interest rates on crypto markets 04:00 Tariffs and their effects on crypto08:24 How USD fluctuations affect global crypto trends 10:15 Investor reactions to a weaker dollar11:58 Bitcoin as a hedge against volatility14:58 The role of traditional investors in driving Bitcoin’s price 20:54 Regulatory insights and which assets stand to gain 22:10 Crypto ETFs24:50 What sets Bitwise apart in the crowded ETF space 26:52 The rise (and slow start) of Ethereum ETFs29:00 How will ETH staking play into demand?30:21 How will an ETH staking fund be structured?32:30 Top crypto assets to watch for the next wave of ETFs 35:25 How index funds are influencing the future of crypto investing 36:50 Crypto native investors38:38 Index funds and the SEC40:11 Ethereum’s coming of age and shifting goals43:45 What can get 1000x users on Ethereum?46:28 Ethereum vs. Solana and the next big trends 48:31 Where and how different blockchains thrive51:30 Predictions for 202553:10 Closing Remarks

Immerse yourself in the future of decentralized infrastructure in this exclusive interview with Amira Valliana from the Solana Foundation. Perfect for Web3 enthusiasts, this episode unpacks how onchain solutions are redefining physical networks, policy, and global collaboration.Chapters & Key Topics: 00:00 Introduction to decentralized infrastructure onchain 00:33 Podcast & guest welcome 03:16 Amira Valliana’s policy work at Solana Foundation 09:19 Shaping blockchain policy and its real-world impact 12:31 What is DePIN? (Decentralized Physical Infrastructure Networks) 15:25 Case Study spotlight: Geonet 18:19 Current tech limits for onchain assets 20:21 Experiments in tracking real-world objects via blockchain 22:00 Supply chain challenges and onchain opportunities 24:08 Using crypto to coordinate worldwide networks 25:38 Helium Network deep-dive 29:00 Future applications for Helium 31:05 Exploring Hivemapper 34:15 Bridging DePIN and AI innovation 38:27 Decentralized AI and infrastructure synergy 42:32 Macro trends (interest rates, tariffs, resources, and more) and their effect 45:43 What’s next for decentralized physical infrastructure?If you’re curious about DePIN, policy in Web3, or the next wave of decentralized AI, you’ll get actionable insights and real-world examples to fuel your curiosity. Subscribe and hit the bell for more interviews with leaders shaping the decentralized future!

Lending and borrowing onchain has quickly become one of the most dynamic and fastest-growing sectors in Decentralized Finance (DeFi). Among the leaders in this space is Maple Finance, a platform that has already facilitated over $800M in assets, showcasing the growing adoption and practicality of tokenized private credit for institutions. By bridging the gap between traditional finance and decentralized systems, Maple Finance is demonstrating how institutions can leverage blockchain technology for more efficient and transparent lending solutions.In an insightful conversation, Camila Russo sat down with Maple Finance’s CEO, Sid Powell, to delve into the potential of real-world assets (RWAs) within DeFi, the evolving role of stablecoins in this ecosystem, and strategies to unlock new lending markets onchain. Their discussion highlights the rapid innovations taking place in the DeFi space and sheds light on the future of decentralized credit markets.

Explore the future of intellectual property on the blockchain in this insightful interview with Jason Zhao. Discover how Story Protocol is revolutionizing the way creators protect, share, and license their work. By bringing IP and copyright onchain, the protocol streamlines the process, ensures compliance with state and national laws, and secures rights in an innovative, transparent manner. Perfect for Web3 creators and blockchain developers ready to push boundaries and unlock new possibilities.Chapters00:00 - Intro: Jason Zhao, Co-founder and Chief Protocol Officer at Story Protocol 00:45 - How Story Protocol is revolutionizing IP management on blockchain 01:16 - Case study: Acquiring Justin Bieber's "Peaches" song rights 02:34 - The vision: Making IP as programmable as stablecoins 05:15 - Jason's background: From AI at DeepMind to blockchain 08:58 - Story's technical architecture: Custom Layer 1 blockchain 11:13 - Proof of Creativity Protocol explained 13:15 - Storing full IP rights and metadata (beyond NFTs) 18:47 - Legal framework and enforceable IP licenses 21:36 - Mainstream IP vs. native Story Protocol IP 24:07 - DeFi integration: Royalties and liquid IP markets 27:31 - How creators monetize their work on Story 29:50 - Tokenomics and the Big Bang staking event 33:51 - Roadmap: IP Portal and future upgrades 37:23 - David Goyer (Dark Knight trilogy) launching new IP on Story 38:28 - Fraud prevention and attestation services 45:02 - Staking mechanics and validator system 49:08 - Meme coins and IP-backed tokens 54:20 - The long-term vision: "HTTP for IP"✨ Check out our new website ✨https://thedefiant.io/🚀 Sign up to our newsletter 🚀https://thedefiant.io/go-premium#pric...🤑 Find DeFi investment opportunities & educational primers herehttps://thedefiant.io/promo?utm_sourc...✊ Follow The DefiantTwitter:  / defiantnews  Discord:  / discord   Instagram:  / thedefiant.io  Telegram: https://t.me/DefiantNews📬 Contact our [email protected]🤝 Sponsorships & [email protected]#TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3

Will Robinson, VP of Engineering at Coinbase, explores the company’s expanding role in decentralized finance (DeFi), highlighting the launch of Bitcoin-backed USDC loans through Morpho and Coinbase’s broader efforts to integrate DeFi solutions. He explains how Coinbase is working to connect centralized finance (CeFi) with DeFi by incorporating decentralized protocols while prioritizing security and regulatory compliance. Robinson also discusses the introduction of cbBTC as an alternative to WBTC, the company’s approach to multi-chain development, and its plans for further DeFi integrations. Additionally, he addresses ongoing debates about Ethereum Layer 2 networks and their impact on the main chain, emphasizing the importance of improved cross-chain interoperability. He also provides insights into Coinbase’s asset listing process, the role of meme coins in the crypto ecosystem, and the company’s broader mission to support a more open and accessible financial system.Chapters00:00 - Intro: Will Robinson, VP of Engineering at Coinbase00:45 - Coinbase’s expanding role in DeFi01:16 - Bitcoin-backed USDC loans powered by Morpho02:34 - How Coinbase enables BTC holders to access liquidity05:15 - Risks involved in Bitcoin-backed loans08:58 - Liquidation risks and loan-to-value ratios11:13 - Early demand and adoption of the product13:15 - cbBTC vs. WBTC: Why Coinbase launched its own Bitcoin wrapper18:47 - How cbBTC is issued and traded21:36 - Coinbase’s approach to self-custody and wallets24:07 - The role of Coinbase Wallet in bridging CeFi and DeFi27:31 - Coinbase’s long-term DeFi strategy and future integrations29:50 - Will DeFi become a mainstream part of traditional finance?33:51 - Coinbase’s evolution from exchange to financial institution34:34 - The rise of Base: How Coinbase grew its Layer 238:28 - Are Layer 2s parasitic to Ethereum?49:08 - The role of meme coins in crypto and Coinbase’s listing process54:20 - The future of on-chain finance and economic freedom✨ Check out our new website ✨https://thedefiant.io/🚀 Sign up to our newsletter 🚀https://thedefiant.io/go-premium#pricing?utm_source=YT&utm_medium=social&utm_campaign=signup🤑 Find DeFi investment opportunities & educational primers herehttps://thedefiant.io/promo?utm_source=YT&utm_medium=social&utm_campaign=alpha✊ Follow The DefiantTwitter: https://twitter.com/defiantnewsDiscord: https://discord.com/invite/3SdRdEs5ag Instagram: https://www.instagram.com/thedefiant.io/Telegram: https://t.me/DefiantNews📬 Contact our [email protected]🤝 Sponsorships & [email protected]#TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3

Bill Barhydt, Founder and CEO of Abra, discusses the evolving landscape of cryptocurrency markets and investment strategies in this week's The Defiant Podcast. He attributes Bitcoin’s price movements to macroeconomic factors, including U.S. monetary policy and liquidity cycles, and notes a growing trend of companies holding Bitcoin on their balance sheets. Barhydt also examines Ethereum’s scalability challenges and the increasing role of DeFi in financial systems, suggesting that decentralized infrastructure could eventually become the standard for banking. Additionally, he expresses optimism about potential regulatory clarity in the U.S., particularly regarding stablecoins and digital asset classifications.Chapters00:00 - Introduction: Bill Barhydt & Abra00:48 - Barhydt’s Background in Crypto & Finance02:23 - How Abra Manages Crypto Wealth05:45 - Bitcoin Loans & Prime Brokerage Explained10:10 - Crypto Market Volatility & Macroeconomic Factors13:24 - Bitcoin Dominance & Altcoin Cycles18:11 - Solana vs. Ethereum: Market Trends & Adoption24:29 - U.S. Crypto Regulations & Policy Predictions36:05 - Trump’s Crypto Involvement39:04 - Institutional Interest in Bitcoin & ETFs50:18 - The Future of DeFi & Traditional Banking52:14 - Barhydt’s Price Predictions54:12 - Final Thoughts & Closing Remarks✨ Check out our new website ✨https://thedefiant.io/🚀 Sign up to our newsletter 🚀https://thedefiant.io/go-premium#pricing?utm_source=YT&utm_medium=social&utm_campaign=signup🤑 Find DeFi investment opportunities & educational primers herehttps://thedefiant.io/promo?utm_source=YT&utm_medium=social&utm_campaign=alpha✊ Follow The DefiantTwitter: https://twitter.com/defiantnewsDiscord: https://discord.com/invite/3SdRdEs5ag Instagram: https://www.instagram.com/thedefiant.io/Telegram: https://t.me/DefiantNews📬 Contact our [email protected]🤝 Sponsorships & [email protected]#TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3

Kain Warwick, founder of Synthetix and Infinex, discusses the evolution of DeFi and the trade-offs required to improve user experience while maintaining decentralization. He explains how Infinex aims to offer a more accessible, centralized exchange-like interface while remaining non-custodial, addressing long-standing UX challenges in DeFi. Warwick also reflects on Synthetix’s recent governance restructuring, competition from Hyperliquid, and the potential shift back to a stablecoin-focused model. Looking ahead, he highlights the importance of regulatory clarity, improved infrastructure, and greater accessibility in driving the next phase of DeFi growth.Chapters00:00 - Introduction to Kain Warwick00:15 - Kain’s history in DeFi01:26 - Motivation behind Infinex and staying in crypto02:21 - Challenges of bull and bear markets05:55 - The idea behind Infinex and UX innovation08:40 - Trade-offs in building a user-friendly DeFi platform17:05 - Passkeys and the seamless user experience24:26 - Adoption metrics and user growth26:51 - Future roadmap: Bitcoin, XRP, and Doge integration33:08 - The Patron NFT sale: Lessons learned37:19 - Synthetix updates: Governance and structural changes39:27 - The role of attention in crypto success47:50 - Synthetix’s stablecoin pivot and liquidity strategy51:14 - Differentiating Synthetix’s stablecoin from others54:03 - Avoiding the pitfalls of past algo stablecoins✨ Check out our new website ✨https://thedefiant.io/🚀 Sign up to our newsletter 🚀https://thedefiant.io/go-premium#pricing?utm_source=YT&utm_medium=social&utm_campaign=signup🤑 Find DeFi investment opportunities & educational primers herehttps://thedefiant.io/promo?utm_source=YT&utm_medium=social&utm_campaign=alpha✊ Follow The DefiantTwitter: https://twitter.com/defiantnewsDiscord: https://discord.com/invite/3SdRdEs5agInstagram: https://www.instagram.com/thedefiant.io/Telegram: https://t.me/DefiantNews📬 Contact our [email protected]🤝 Sponsorships & [email protected]#TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3

Preston Van Loon, an Ethereum core developer, joins The Defiant Podcast this week to discuss his role as a plaintiff in the high-profile Tornado Cash lawsuit against the U.S. Treasury’s Office of Foreign Assets Control (OFAC). He described how the sanctions imposed on Tornado Cash impacted legitimate users seeking privacy on Ethereum and underscored the significance of a recent appellate court ruling questioning whether smart contracts qualify as “property” under U.S. sanctions law. Van Loon also noted the possibility of a friendlier regulatory environment in the United States, suggesting that changing policy stances could spur crypto innovation. Finally, he addressed ongoing discussions within the Ethereum community about development priorities, governance structures, and the challenges of maintaining a decentralized protocol as the ecosystem grows. Chapters 00:00 - Introduction and Background 01:15 - What is Tornado Cash? 04:00 - Why Tornado Cash Was Sanctioned 06:45 - Filing the Lawsuit 09:50 - Court Ruling and Implications 14:00 - Next Steps in the Legal Case 18:00 - Privacy Rights and Crypto 24:00 - Impact on Builders and Industry 34:00 - Ethereum's Role and Future Challenges 50:00 - Community Feedback and Leadership 55:00 - Closing Remarks Our sponsors https://node.icn.global/?utm_source=TheDefiant&utm_medium=paid&utm_campaign=node_sale_live https://kelpdao.xyz/gain/growth-vault/?utm_source=Defiant https://betteron.stellar.org/ ✨ Check out our new website ✨ https://thedefiant.io/ 🚀 Sign up to our newsletter 🚀 https://thedefiant.io/go-premium#pricing?utm_source=YT&utm_medium=social&utm_campaign=signup 🤑 Find DeFi investment opportunities & educational primers here https://thedefiant.io/promo?utm_source=YT&utm_medium=social&utm_campaign=alpha ✊ Follow The Defiant Twitter: https://twitter.com/defiantnews Discord: https://discord.com/invite/3SdRdEs5ag Instagram: https://www.instagram.com/thedefiant.io/ Telegram: https://t.me/DefiantNews 📬 Contact our Newsroom [email protected] 🤝 Sponsorships & Partnerships [email protected] #TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3

Sam Kazemian, founder of Frax Finance, outlined the development and goals of FraxUSD, a decentralized stablecoin designed to integrate with both traditional finance and decentralized ecosystems. The upgraded FraxUSD offers redeemability through custodians like BlackRock and SuperState while providing competitive yields through diversified strategies. Kazemian described Frax’s broader vision as building a digital economy anchored by its flagship stablecoin and Fraxstool, a high-performance Ethereum Layer 2. Chapters 00:00 - Introduction 00:48 - Founding Story and Differentiation of Frax 02:01 - Vision for Decentralized Stablecoins 02:41 - Features of FraxUSD 08:51 - Best of Both Worlds Design for FraxUSD 13:08 - Future of Stablecoins 23:05 - Yield Strategy of FraxUSD 34:16 - FraxUSD in Real World and On-Chain Usage 42:02 - Stablecoins as the Gateway to Crypto 47:12 - Roadmap and Future of Frax ✨ Check out our new website ✨ https://thedefiant.io/ 🚀 Sign up to our newsletter 🚀 https://thedefiant.io/go-premium#pricing?utm_source=YT&utm_medium=social&utm_campaign=signup 🤑 Find DeFi investment opportunities & educational primers here https://thedefiant.io/promo?utm_source=YT&utm_medium=social&utm_campaign=alpha ✊ Follow The Defiant Twitter: https://twitter.com/defiantnews Discord: https://discord.com/invite/3SdRdEs5ag Instagram: https://www.instagram.com/thedefiant.io/ Telegram: https://t.me/DefiantNews 📬 Contact our Newsroom [email protected] 🤝 Sponsorships & Partnerships [email protected] #TheDefiant​ #DeFi​ #Decentralized​ #Finance​ #Blockchain #Web3