Evidence-Based GI: An ACG Publication and Podcast

Leandro Sierra, MD is joined by Anna S. Lok, MD to discuss key points from the recent AASLD/ISDA Practice Guideline on treatment of chronic hepatitis B. (30:40)

Leandro Sierra, MD is joined by author Jasmohan S. Bajaj, MD, MS, FACG to discuss the recent ACG Clinical Guideline on Hepatic Encephalopathy, published in the March 2026 issue of the American Journal of Gastroenterology.

Associate Editor Elie Al Kazzi, MD, MPH and Vasantham Chaudhary, MD discuss "Appendicectomy versus switching to a JAK inhibitor in inducing remission in patients with active ulcerative colitis after biologic therapy failure (COSTA): 1-year results of a multicentre, prospective, cohort study, by Visser E, Reijntjes MA, Heuthorst L, et al. Published in Lancet Gastroenterol Hepatol. 2026 Mar;11(3):190-203.

Associate Editor Elie Al Kazzi, MD, MPH and Vasantham Chaudhary, MD discuss "Global Consensus Statement on the Management of Pregnancy in Inflammatory Bowel Disease," by Mahadevan U, Seow CH, Barnes EL, et al. Published in Am J Gastroenterol, August 27, 2025.

Leandro Sierra, MD interviews author Zachary Fricker, MD on "ACG Clinical Guideline: Perioperative risk assessment and management in patients with cirrhosis," by Mahmud N, Fricker ZP, McElroy LM, Qayed E, Wong RJ, Ioannou GN. Published in Am J Gastroenterol, 2025;120:1968-1984.

Christopher Vélez, MD and Noor Syed, MD discuss "The Efficacy and Safety of Tacrolimus in Reducing Inflammation and Need for Dilation," by Kukreja K, Kumar A, Camisa C, Jacobs J, Richter JE. Published in Clin Transl Gastroenterol, 2024 Dec 1;15(12):e00752.

Vasantham Chaudhary, MD and Elie Al Kazzi, MD, MPH discuss "Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)," by Te Groen M, Wijnands AM, den Broeder N, et al. Published in Gut 2025;75:547-556.

Leandro Sierra, MD and Joseph Lim, MD discuss "Early antiviral treatment with tenofovir alafenamide to prevent serious clinical adverse events in adults with chronic hepatitis B and moderate or high viraemia (ATTENTION): interim results from a randomised controlled trial,” by Lim Y. S., Yu M. L., Choi J., et al. Published in Lancet Gastroenterol Hepatol 2025; 10(4):295-305.

Rachael Hagen, MD and Joseph C. Anderson, MD, FACG discuss "Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer,” by Jacobson BC, Anderson JC, Burke CA, Dominitz JA, Gross SA, May FP, Patel SG, Shaukat A, Robertson DJ. Published in Am J Gastroenterol. 2025: 120(4):738-764.

Ellen Axenfeld, MD and Elie Al Zazzi, MD, MPH discuss "Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Peyrin-Biroulet L, et al and the ARTEMIS-UC Study Group. Published in N Engl J Med. 2024 Sep 26;391(12):1119-1129.