Dr. Joseph Mercola - Take Control of Your Health podcast

Your Gut Nervous System Helps Regulate Intestinal Barrier and Allergy Risk

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  • Your gut's nervous system directly influences whether you tolerate foods or react to them, making it a key factor in food sensitivities and allergy risk
  • A tiny nerve messenger called the vasoactive intestinal peptide (VIP) tells your gut stem cells how to rebuild the intestinal lining; when VIP drops, your gut produces too many tuft cells that trigger allergy like inflammation
  • Everyday exposures — like microplastics, seed oils, and emulsifiers found in processed foods — damage tight junction proteins, weaken your gut barrier, and increase the flow of irritants into your bloodstream
  • Low vitamin D, disrupted sleep, and high stress interfere with your gut's ability to maintain barrier integrity and calm immune activity, raising your vulnerability to allergic reactions
  • You can lower your allergy risk by supporting mitochondrial function, removing gut damaging triggers, restoring healthy carbs in the right order, and improving the nerve-gut connection that regulates intestinal healing

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