Dr. Joseph Mercola - Take Control of Your Health podcast

Stress Alters Metabolic Hormone with Health Consequences, Study Shows

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  • Research from Columbia University shows that psychological stress changes a key metabolic hormone, linking emotional strain directly to energy production and overall health
  • People with healthy mitochondria experience a drop in this hormone under stress, while those with mitochondrial dysfunction show an increase — demonstrating how cellular energy capacity shapes stress resilience
  • Chronic stress overstimulates classic stress hormones like cortisol and adrenaline, disrupting blood sugar control, promoting fat storage, and exhausting your mitochondria — the engines that power every cell
  • Social isolation and loneliness were linked to higher levels of stress-related hormones, suggesting that emotional well-being and physical metabolism are deeply connected
  • Restoring mitochondrial balance through nutrition, regular movement, deep sleep, and meaningful connection helps calm stress chemistry, boost energy, and slow biological aging

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