Stroke Alert March 2025

On Episode 51 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the April 2025 issue of Stroke: “Clinical Severity and Outcomes in Large Infarcts With Endovascular Therapy: A Post Hoc Analysis of the ANGEL-ASPECT Trial” and “Association Between Thrombus Composition and Etiology in Patients With Acute Ischemic Stroke Treated by Thrombectomy.” She also interviews Dr. Roland Veltkamp about the PRESTIGE-AF trial, presented in February at the International Stroke Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250414.579089

On Episode 50 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the March 2025 issue of Stroke: “Impact of Subarachnoid Hemorrhage on Human Glymphatic Function: A Time-Evolution Magnetic Resonance Imaging Study” and “Thrombolysis for Ischemic Stroke Beyond the 4.5-Hour Window: A Meta-Analysis of Randomized Clinical Trials.” She also interviews Drs. Mayank Goyal and Michael Hill about the ESCAPE-MeVO trial, presented in February at the International Stroke Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250314.838310

On Episode 49 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the February 2025 issue of Stroke: “Safety of Adjunctive Intraarterial Tenecteplase Following Mechanical Thrombectomy: The ALLY Pilot Trial” and “Large-Scale Plasma Proteomics Profiles for Predicting Ischemic Stroke Risk in the General Population.” She also interviews Drs. Tao Wang and Yan Ma about their article “Determining the Optimal Age for Extracranial-Intracranial Bypass Surgery: A Post Hoc Analysis of the CMOSS Randomized Trial.” For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250212.411369

On Episode 48 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2025 issue of Stroke: “Hypoglycemic Events May Trigger Acute Ischemic Stroke Within 30 Days in Those With Diabetes: A Case-Crossover Study” and “Efficacy and Safety of a Dedicated Device for Cerebral Venous Thrombectomy: A Pilot Randomized Clinical Trial.” She also interviews Drs. Johanna Ospel and Umberto Pensato about their article “Cerebral Infarct Growth: Pathophysiology, Pragmatic Assessment, and Clinical Implications.” For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250113.68216

On Episode 47 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Ashutosh Jadhav, Professor of Neurology and Neurosurgery at the Barrow Neurological Institute, for the 2024 Ralph Sacco Review of Top Cerebrovascular Research. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke, who died in January 2023, Drs. Asdaghi and Jadhav review some of the top cerebrovascular science published in any journal or presented at any scientific forum throughout the past year. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241213.415139

On Episode 46 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2024 issue of Stroke: “Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review” and “Oxygen Extraction Fraction Mapping on Admission Magnetic Resonance Imaging May Predict Recovery of Hyperacute Ischemic Brain Lesions After Successful Thrombectomy: A Retrospective Observational Study.” She also interviews Drs. Mitch Wilson and Vasileios-Arsenios Lioutas about their article “Association of Anticoagulant Use With Hemorrhage Location and Etiology in Incident Spontaneous Intracerebral Hemorrhage.” For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241112.907388

On Episode 45 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2024 issue of Stroke: “Cigarette Smoking and Observed Growth of Unruptured Intracranial Aneurysms: A Systematic Literature Review and Meta-Analysis” and “Clinical and Prognostic Characteristics of Acute BAD–Related Stroke: A Multicenter MRI–Based Prospective Study.” She also interviews Dr. Vignan Yogendrakumar about his article “Emerging Adjuvant Thrombolytic Therapies for Acute Ischemic Stroke Reperfusion.” For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241007.116951

On Episode 44 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2024 issue of Stroke: “Stroke Risk After Emergency Department Treat-and-Release Visit for a Fall” and “Higher Risk of Mental Illness in Patients with Diagnosed and Untreated, Unruptured Intracranial Aneurysm: Findings from a Nationwide Cohort Study.”  She also interviews Dr. Yutong Chen and Professor Hugh Markus about the article “Improved Dementia Prediction in Cerebral Small Vessel Disease Using Deep Learning–Derived Diffusion Scalar Maps From T1,” published in Stroke. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240913.368707

On Episode 43 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2024 issue of Stroke: “Diagnostic Accuracy of Posterior/Anterior Periventricular WMH Ratio to Differentiate CAA From Hypertensive Arteriopathy” and “Statin Overuse in Cerebral Ischemia Without Indications: Systematic Review and Annual US Burden of Adverse Events.” She also interviews Dr. Gang Li about the article “Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke,” published in The New England Journal of Medicine. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240726.908961

On Episode 42 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2024 issue of Stroke: “Dual Antiplatelet Therapy After Embolic Stroke of Undetermined Source: A Subgroup Analysis of the CHANCE-2 Trial” and “Risk of Stroke in Women Using Levonorgestrel-Releasing Intrauterine Device for Contraception.” She also interviews Dr. Manabu Inoue about his article “Expanding the Treatable Imaging Profile in Patients With Large Ischemic Stroke: Subanalysis From a Randomized Clinical Trial.”