Does thalidomide alter DNA?

Thanks to John Travers for the answer!Listener Francisco asked: I have been told that jumping on a trampoline is healthy for humans. It is considered as a good exercise; and also to better coordinate brain and body. I am 73 and wonder whether it is advisable for me to jump on a spring board?John - My work in reversing frailty and building resilience in older adults has made me a big advocate for resistance exercises like trampolining. This should be combined with consuming sufficient protein to turn that work into stronger muscles and bones. Jumping on a trampoline can improve cardiovascular... Like this podcast? Please help us by supporting the Naked Scientists

Silke is writing all the way from French Polynesia, asking what's best to do with all the plastic rubbish she picks up from the beach, and whether burning it is advisable. James Tytko asked Richard Lampitt from the National Oceanography Centre to help find an answer... Like this podcast? Please help us by supporting the Naked Scientists

Listener to the show, Elaine, wants to know whether her mother, who was a thalidomide baby, might have passed on effect of the drug to her children. Thalidomide was a treatment for morning sickness which caused severe birth differences in children born to mothers who used the drug. James Tytko sought an answer, with help from Neil Vargesson, Professor of Developmental Biology at the University of Aberdeen... Like this podcast? Please help us by supporting the Naked Scientists

Garth wants to know, given the skin can block water from passing through it, how do certain skin creams allege to permeate into our body? James Tytko took on the question with help from Richard Guy, Professor of Pharmaceutical Sciences at the University of Bath... Like this podcast? Please help us by supporting the Naked Scientists

Garth writes in wanting to know why the prevalence of lactose intolerance is nearly 100% in countries like South Korea, but down in the low single digits in countries like the UK. James Tytko asked Mark Thomas, Professor of Evolutionary Genetics at UCL, for the answer... Like this podcast? Please help us by supporting the Naked Scientists

Dan wants to know what the likelihood is of him being here if neither him, his parents, nor his grandparents had had any vaccinations. James Tytko sought to provide an answer, with the help of Helen Bedford, Professor of Children's Health at UCL... Like this podcast? Please help us by supporting the Naked Scientists

Thanks to Philippa Browning for the answer! Like this podcast? Please help us by supporting the Naked Scientists

Bill sends his question in all the way from Australia. A regular listener, he enjoys our programme through bone conduction headphones. But what are these devices, and does listening to loud sounds through them predispose a person to damaging their hearing in the same way as traditional headphones? James Tytko seeks the answers, with help from audiologist Roger Lewin... Like this podcast? Please help us by supporting the Naked Scientists

Kevin wants to know, assuming many of us will be driving electric cars in the future, what will happen to the vast quantities of petrol currently refined from crude oil? Will we scale back production? Or can industry adapt? To help James Tytko with the answer, we hear from Professor Nilay Shah, Director of the Centre for Process Systems Engineering at Imperial College London... Like this podcast? Please help us by supporting the Naked Scientists

George writes in to ask whether his gum-chewing habits are related to his tinnitus, or whether it's just a coincidence that it comes back when he gets back into the habit. James Tytko investigates, with help from ear, nose and throat doctor Malcolm Hilton... Like this podcast? Please help us by supporting the Naked Scientists