Chagas disease: Test for cure

Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. Nuisance blood-sucking insects known as kissing bugs spread the parasite to humans when exposure to their feces penetrates the mucus membranes, breaches the skin or gets orally ingested. Researchers from the University of Florida Emerging Pathogens Institute and Texas A&M University gathered their resources to investigate the potential of vector-borne transmission of Chagas in Florida.The 10-year-long study, published in the Public Library of Science Neglected Tropical Diseases, used data from Florida-based submissions, as well as field evidence collected from 23 counties across Florida. Joining me today to talk about the study and their findings is Norman Beatty, MD. Dr Beatty is an Assistant Professor of Medicine at the University of Florida College of Medicine. He is also a member of the Emerging Pathogens Institute at the University of Florida.     Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA

Rhodesia, now Zimbabwe since 1980, is a landlocked country in Southeast Africa. From 1978-1980, Rhodesia experienced one of the largest anthrax epidemics in recorded history. This led to the deaths of hundreds and caused significant economic devastation. The epidemic happened during the Rhodesian Bush War. To this day, the origins of this devastating outbreak remain highly controversial- was it the result of an endemic outbreak or a case of biological warfare? Today I’m going to look at the history of the epidemic and the possible causes with Matthew Turner, MD. Dr Turner is with the Department of Emergency Medicine at Penn State Health Milton S. Hershey Medical Center in Hershey Pennsylvania. He is also the author of an article on the topic published in the Cureus Journal of Medical Science.     The Rhodesian Anthrax Epidemic: A Case of Biological Warfare?

Chagas disease is a dangerous tropical illness caused by single-cell parasites known as Trypanosoma cruzi. In most cases, if not treated immediately, the infection becomes chronic: the immune system of the host greatly reduces the number of parasites present in the body yet fails to fully eradicate them. Current diagnostic approaches often fail to detect these low numbers of parasites. A research team from the University of Georgia and others aimed to develop a test for cure.  Joining me today is Rick Tarleton, PhD. Dr Tarleton ia a Regents’ Professor at the University of Georgia and a Distinguished Professor in Biological Sciences in the Department of Cellular Biology.     Serial ‘deep-sampling’ PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected human, macaque, and canine hosts, and allows accurate monitoring of parasite load following treatment

Rat lungworm disease is on the rise in eastern Australia in dogs – and there have even been recorded cases in humans, including two known lethal incidents. Research by veterinary scientists at the University of Sydney has unveiled insights into what is behind the growth in the disease, also known as neural angiostrongyliasis. Their study, published in The Journal of Infectious Diseases, highlights how climatic factors act as drivers for this potential public health issue. Joining me to discuss this is Professor Jan Slapeta, Dr Slapeta is a Professor of Veterinary and Molecular Parasitology at the University of Sydney and senior author of the paper.   Rainfall- and Temperature-Driven Emergence of Neural Angiostrongyliasis in Eastern Australia, 2020–2024

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