Primary Motor Cortex Involvement and Seizure Risk in Patients With Brain Metastases

Dr. Justin Abbatemarco and Dr. Irene Cortese discuss recent advances in the treatment of progressive multifocal leukoencephalopathy (PML), focusing on immune-based therapies like virus-specific T cells and immune checkpoint inhibitors.  Show citation:  Gonzalez CE, Fletcher A, Jenkins TL, et al. Resolution of PML after Treatment with Virus-Specific T Cells and HCT. N Engl J Med. 2026;394(20):2061-2064. doi:10.1056/NEJMc2514186 

Dr. Kait Nevel and Drs. Ayal Aizer and Clara Baselga-Garriga discuss the link between primary motor cortex involvement in brain metastases and increased seizure risk. Show citation:  Baselga-Garriga C, Purohit S, Lamba N, et al. Primary Motor Cortex Involvement and Its Association With Seizure Risk in Patients With Brain Metastases. Neurology. 2026;106(7):e214714. doi:10.1212/WNL.0000000000214714

In part two of this nine-part series, Dr. Christine Cliatt-Brown discusses Capgras syndrome. 

In part one of this nine-part series, Dr. Christine Cliatt-Brown provides an overview of delusional misidentification syndromes. 

In the final episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss the complex role of TNF alpha inhibition in tuberculosis treatment and the use of infliximab and other targeted therapies to manage inflammation. 

In this episode, Dr. Jose Posas reviews the Capitol Hill Report from September 7th, discussing the busy month ahead for Congress, BrainPAC, and a couple of other advocacy news items.  Stay updated with what's happening on the hill by visiting aan.com/chr.  Learn how you can get involved with AAN advocacy. 

In part two of this series, Dr. Aaron Zelikovich and Dr. Bhaskar Roy discuss recommendations to help neurologists navigate the expanding landscape of myasthenia gravis treatments.  Show citation:  McLaren NP, Rosati M, Zhong W, et al. Comparison of the Efficacy and Safety of Myasthenia Gravis Treatments: A Bayesian Network Meta-Analysis. Neurology. 2026;107(3):e218351. doi:10.1212/WNL.0000000000218351  

In the second episode of this series, Dr. Justin Abbatemarco and Dr. Sara Marceglia discuss the risks of incorporating AI into clinical practice.  Show citation:  Vozzi C, Sibilla M, Sandri D, et al. Education Research: Bridging the Artificial Intelligence Training Gap: Evidence from a National Survey of Italian Neurology Residents. Neurol Educ. 2026;5(1):e200289. Published 2026 Jan 27. doi:10.1212/NE9.0000000000200289  

In the sixth episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss high-dose rifampin in TB meningitis. 

In part one of this series, Dr. Justin Abbatemarco and Dr. Alberto Priori discussed the use of artificial intelligence in neurology among peers, not just trainees.  Show citation:  Vozzi C, Sibilla M, Sandri D, et al. Education Research: Bridging the Artificial Intelligence Training Gap: Evidence from a National Survey of Italian Neurology Residents. Neurol Educ. 2026;5(1):e200289. Published 2026 Jan 27. doi:10.1212/NE9.0000000000200289