#205 - Nihilistic Depression (Part 1)

In this episode we get deeper into Dr. Macphee and Dr. Dreier's treatment for depression and discuss our own challenges with patients who find their world lacking meaning.Hosts: Eyrn, Al, Yas, RiverGuests: Edward Macphee, MD, Amy Dreier, PhD

In this episode we discuss nihilism and the complexities around treatment for nihilistic depression, as well as laying the groundwork for Dr. Macphee and Dr. Dreier's new interventional model.Hosts: Eyrn, Al, Yas, RiverGuests: Edward Macphee, MD, Amy Dreier, PhD

Al shares with the group about the experience of getting a one-star rating. Toshia shares her experiences, Yas brings some data on physician ratings and how they may be a good thing with some serious unintended negative consequences for patient care.Hosts: Alan Atkins, MD, Toshia Ann Yamaguchi, MD, Yasmine Dakhama, MD

Dr. Jennifer Hagman joins us again to talk about the thought patterns that lock in for patients with eating disorders. We focus today on bulimia nervosa and the difficulties of treating it. Hosts: Alan Atkins, MD, Yasmine Dakhama, MDGuest: Jennifer Hagman, MD

In today's episode, we discuss cultural factors associated with eating disorders with Dr. Jennifer Hagman.  She also tells us about the history behind Avoidant/Restrictive Food Intake Disorder and the physiology of binge eating.Hosts: Alan Atkins, MD, Yasmine Dakhama, MDGuest: Jennifer Hagman, MD

More on lavender with our return guest, Dr. Aiken from the Carlat Psychiatry Podcast.Hosts: Al, ToshiaGuest: Chris Aiken, MD

Join us for a fascinating discussion on lavender with our return guest, Dr. Aiken from the Carlat Psychiatry Podcast.Hosts: Al, ToshiaGuest: Chris Aiken, MD

Stimulant medication has been widely prescribed to treat ADHD effectively for decades. But is the impact for a person more than just greater focus and attention? Does it change a person's understanding of oneself, one's relationships, and overall approach to life--i.e. one's personality? Listen to our open discussion of this question with the LGP team and our guest, psychiatrist and Stanford professor, Dr. John Leikauf.Hosts: Eyrn, Al, ToshiaGuest: John E. Leikauf, MDResourcesFantozzi P, Muratori P, Caponi MC, Levantini V, Nardoni C, Pfanner C, Ricci F, Sesso G, Tacchi A, Milone A, Masi G. Treatment with Methylphenidate Improves Affective but Not Cognitive Empathy in Youths with Attention-Deficit/Hyperactivity Disorder. Children (Basel). 2021 Jul 14;8(7):596. doi: 10.3390/children8070596. PMID: 34356575; PMCID: PMC8307630.Kirkpatrick MG, Johanson CE, de Wit H. Personality and the acute subjective effects of d-amphetamine in humans. J Psychopharmacol. 2013 Mar;27(3):256-64. doi: 10.1177/0269881112472564. Epub 2013 Jan 23. PMID: 23343596; PMCID: PMC4241296.Leikauf, John E., et al. "Attention-Deficit/Hyperactivity Disorder Subtypes Defined by Cognition Have a Distinct Neural and Clinical Profile and Differ in Response to Atomoxetine." Journal of the American Academy of Child & Adolescent Psychiatry, 2025, https://doi.org/10.1016/j.jaac.2025.07.007.Maoz H, Gvirts HZ, Sheffer M, Bloch Y. Theory of Mind and Empathy in Children With ADHD. J Atten Disord. 2019 Sep;23(11):1331-1338. doi: 10.1177/1087054717710766. Epub 2017 May 30. PMID: 28558473.Takım U, Belli H, Gökçay H, Köse H, Arslan Akgül H, Çakır A. Examination of Changes in Levels of Empathy and Narcissistic Pathology After Treatment of Adult with Attention-Deficit/Hyperactivity Disorder. Alpha Psychiatry. 2024 Sep 1;25(5):598-603. doi: 10.5152/alphapsychiatry.2024.241630. PMID: 39553487; PMCID: PMC11562234.

What is the relationship between AI and psychosis? Do chatbots help or hurt? We explore these questions with the Director of Stanford's child psychosis clinic (INSPIRE), Dr. Apurva Bhatt, and researcher with lived experience, Shannon Pagdon. Hosts: Eyrn, AlGuests: Apurva Bhatt, MD, and Shannon Pagdon, MSW/PhD student

In this episode, Dr. Jade Sasser joins us for another episode to discuss the 2025 Los Angeles wildfires and the associated climate anxiety, as well as reproductive justice and specifically how climate change contributes to a hesitancy to have children in younger generations. Hosts: Eyrn, Toshia, Al, & YasmineGuest: Dr. Jade Sasser, MA, MPH, PhD