Impact of Loop Diuretics on Long-Term Kidney Outcome: A Post-Hoc Analysis of the STOP-ACEi Trial

In 11,409 adults with CKD and no prior heart failure, three standard ECG features independently predicted new-onset HF hospitalization. The findings support routine ECG as a low-cost adjunct to existing HF risk assessment in CKD.

Sickle cell disease causes accelerated kidney function decline, yet proven GFR-preserving therapies remain elusive. In this study of adults with sickle cell disease, RASi use was not associated with a significant difference in the rate of eGFR decline.

This podcast discusses a post hoc analysis of the STOP-ACEi trial, examining whether baseline loop diuretic use modifies the effect of Renin–Angiotensin System Inhibitors in advanced CKD.

This episode highlights data from a qualitative substudy of the AV Access trial, a randomized controlled trial studying outcomes of older adults who are receiving hemodialysis with a central venous catheter.

Dialysis in infants with ESKD is often associated with multiple comorbidities and the need for more intensified dialysis regimens. This study found that infant ESKD is associated with significant health care utilization.

This podcast discuss findings from a prospective cohort of patients with severe and symptomatic ESKD requiring an urgent start of HD or PD owing to uremic syndrome, where both modalities offered similar outcomes.

This episode discusses a retrospective single-center study examined the effects of socioeconomic status on preemptive kidney transplantation in children.

The Shared Decision-Making-Renal Supportive Care intervention elicited dialysis patient preferences for end-of-life care. The HIGHWay project updated this intervention to scale it for broader implementation of advance care planning.

This episode discusses a study that measured objective nocturnal sleep duration of patients on hemodialysis and characterized natural and dialysis-imposed patterns of sleep duration using a commercially available wearable activity tracker.

Data from nearly 16,000 French peritoneal dialysis (PD) patients were analyzed in this large observational study, to understand factors influencing transfers to hemodialysis for different reasons.