Brain Biomarkers | Mild-Mod COVID Treatments

The JournalFeed podcast for the week of July 21-25, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:Novel blood-based biomarkers, specifically GFAP, UCH-L1, S100B, and NfL, may be well suited for early classification and triage of patients with acute and subacute minor traumatic brain injury.Tuesday Spoon Feed:To reduce hospitalizations of patients with mild to moderate COVID, treat with nirmatrelvir-ritonavir (Paxlovid) or remdesivir. To shorten the duration of COVID symptoms, azithroycin, favipiravir, molnupiravir, umifenovir, or corticosteroids may help, but they are not standard of care. 

The JournalFeed podcast for the week of July 14-18, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:A single high-quality CT scan is highly accurate at detecting serious cervical spine injuries in children after trauma and may be enough to clear the spine without further imaging safely in majority of patients.Thursday Spoon Feed:For patients with ROSC after OHCA who required vasopressors transported by Finnish helicopter EMS (HEMS), normotension (100-140 mm Hg) was associated with improved 30-day mortality compared to hypo and hypertension.Friday Spoon Feed:This study of a trauma database found patients intubated in the emergency department (ED) who required hemorrhage control surgery had worse outcomes than those who were intubated in the operating room (OR). However, a study published just two months ago, from the same database of patients, found no difference in patients based on intubation location. What gives?

The JournalFeed podcast for the week of July  7-11, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:Targeting the 5th percentile mean blood pressure in pediatric septic shock resulted in similar 28-day mortality as targeting the 50th percentile - while reducing vasopressor use, side effects, and complications like ARDS.Friday Spoon Feed:This study shows that ketamine alone is a safe choice for pediatric sedation in the ED, with serious adverse events (AE) occurring rarely, primarily in older children or when opioids are coadministered.

The JournalFeed podcast for the week of June 30 - July 4, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:Patients with mild asthma who used albuterol-budesonide rescue therapy had about half as many severe exacerbations as those on albuterol alone.Thursday Spoon Feed:In ED patients with bone fractures, intranasal ketamine provided pain relief comparable to IV ketamine and morphine, with no significant differences in efficacy or adverse effects across groups.

The JournalFeed podcast for the week of 23-27, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Wednesday Spoon Feed:Bayesian analysis of the use of EpiDex in bronchiolitis demonstrates a reduced probability of hospitalization for bronchiolitis, although highly skeptical clinicians may require additional evidence.Friday Spoon Feed:Over half of transferred patients with facial fractures don’t need treatment or admission. This study proposes smart, evidence-based guidelines – Facial Injury Guidelines, or FIG – to help healthcare systems save money, time, and beds (and maybe a few ambulance rides), pending future validation.

The JournalFeed podcast for the week of June 16-20, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:Prolonged central capillary refill time is associated with increased mortality in adult trauma patients—including those with “stable” initial vital signs.Wednesday Spoon Feed:This external validation of the Falls decision making tool for older adult patients with head trauma found a high degree of sensitivity and negative predictive value while reducing unnecessary CT scans by almost 32%. 

The JournalFeed podcast for the week of June 9-13, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Wednesday Spoon Feed:A retrospective study found that trauma patients who were intubated in the ED had no difference in morality compared to those intubated in the OR on propensity matched analysis. Thursday Spoon Feed:In a large cross-sectional study, cannabis use—particularly daily use—was independently associated with increased risk of myocardial infarction, stroke, and composite cardiovascular outcomes, even among never-tobacco users and younger adults.

The JournalFeed podcast for the week of June 1-6, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:In this retrospective study of 74 peritonsillar abscess (PTA) patients, there were no instances of inadvertent carotid puncture.Tuesday Spoon Feed:Ingesting household bleach rarely causes esophageal or gastric injury in children, making routine endoscopy unnecessary in most cases.

The JournalFeed podcast for the week of 26-30, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:A novel termination of resuscitation (TOR) rule for in-hospital cardiac arrest (IHCA) utilizing information available at the bedside proposed TOR appropriately, often, and rarely misidentified survivable cases.Friday Spoon Feed Spoon Feed:Electronic Dance Music Festivals(EDMF) are associated with a higher medical utilization rate (MUR) when compared with other mainstream events. EDMF attendees are also likely to be sicker and present more frequently with drug related concerns. 

The JournalFeed podcast for the week of 19-23, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:The Ten Test is a quick, reliable, no-equipment sensory exam that performed as well as or better than traditional methods in assessing hand and finger injuries – with none of the cost.Friday Spoon Feed:In this Bayesian network meta analysis, researchers compared pharmacologic interventions for migraine treatment. There was no clear superior choice for single-agent pain control, but chlorpromazine IV/IM was among the most effective for adequate pain relief at two hours, and IV/IM ketorolac was possibly among the worst.