76. The History of Rapamycin and mTOR. David Sabatini’s journey to discovering mTOR.

https://www.nejm.org/doi/full/10.1056/NEJMoa2204233

SURMOUNT 1 Trial. The aim of this trial was to investigate the safety and efficacy of Tirzepatide, a novel GLP + GIP in people with obesity. We discuss the trial in this episode.

@ michaelsalzle Patients with diabetes and chronic disease are at high risk for kidney failure, cardiovascular events, and death. The FLOW trial looked at the safety and efficacy of semaglutide in patients with chronic disease and type 2 diabetes.

@michaelsalzlePreservation of your immune system, mind, and muscle

@michaelsalzle In this episode, we learn how to preserve our bones, bowel, circulation, hair, hearing, and hormones.

@michaelsalzle

@michaelsalzle

@michaelsalzle

@michaelsalzle. In this episode, we discussed pathways of aging. We discuss the importance of genes, AMPK, autophagy, metformin, foods that boost AMPK, autophagy, foods that boost autophagy, spermidine,epigenetics, and cellular senescence

@michaelsalzle