
Why Every Woman Over 40 Should Know About Creatine
Episode Summary
Women have up to 70-80% lower creatine stores than men — and most of us have never been told that. In this episode Lisa digs into what that means for your brain, sleep, mood, muscles, and energy, and why creatine may be one of the most underreported tools in women's health right now.
What You'll Learn
- What creatine actually is and why it matters beyond the gym
- Why women have lower creatine stores — and why that gap widens in perimenopause
- How creatine supports brain energy (ATP) and what happens when levels run low
- The research on creatine and memory, processing speed, and mental clarity
- Why creatine may reduce depression symptoms — more so in women than men
- Creatine and sleep: the adenosine mechanism, the 2024 women's RCT, and the 2025 perimenopause findings
- The University of Kansas Alzheimer's pilot study
- Creatine + resistance training for muscle and bone health over 40
- How much to take: 5g for general health vs. 10g for brain-specific benefits
Start Here
Ready to heal your metabolism? thinlicious.com/happy
Studies Referenced
Cognitive Function & Memory
Depression in Women
Systematic Review & Meta-Analysis: Creatine for Depression (2025). British Journal of Nutrition.
Sleep
Alzheimer's Disease
Brain Dosing: The Case for 10g
Dr. Rhonda Patrick on 10g brain dosing (@foundmyfitness)
Medical Disclaimer: For educational purposes only. Not medical advice. Always consult your doctor before starting any new supplement.
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