DOCSF 2023: Novel Regenerative Drug Candidate for Osteoarthritis of the Knee

In this episode, Stefano Bini interviews Douglas Fairbanks, CEO of VISIE, on the Digital Orthopedics Podcast. VISIE, a partner and supporter of the Digital Orthopedics Conference San Francisco, unveiled their groundbreaking "continuous anatomic auto-tracking technology" at DOCSF 2024. Visie shares how they can revolutionize surgical robotic accuracy by enabling real-time 3D scanning of bone and soft tissue without pins or markers, a common challenge in orthopedic procedures.Fairbanks highlights how VISIE’s latest system adapts instantly to continuous movements like knee flexion. This innovation frees surgeons from constant manual adjustments and rechecks, enhancing efficiency and precision while hopefully reducing procedural complications.Discover how VISIE is shaping the future of digital surgery and advancing personalized care.

In this new season of DOCSF - The Webinar Series, hosted by Stefano Bini, we explore the world of AI in orthopedics. Our expert panel discusses fine-tuning models, data privacy, and clinician involvement. The conversations emphasize the importance of clear definitions, transparency, and human feedback in healthcare AI. One of the main takeaways is the holistic evaluation of AI's value for optimizing healthcare outcomes and workflows.Join us as we delve into challenges like low profit margins and data ownership, with innovative ideas like patient data monetization and blockchain. Now, it's your turn to take action. Stay informed, engage with AI in healthcare, and be part of the transformation towards a healthier future.

In this new season of the DOCSF conference, we are bringing you a series of webinar shows, which serve as an extension of the DOCSF conference.The focus is on exploring the exciting potential of generative AI. The panel delves into how generative AI can reshape various industries, with a particular spotlight on its applications in healthcare. Topics covered include its knowledge-absorption capabilities, its effectiveness with unstructured data, and the challenges of ensuring AI can discern between meaningful and irrelevant information. The discussions also emphasize how generative AI can enhance healthcare processes, like note creation and operational efficiency while underlining the importance of safety precautions. The season aims to shed light on AI's ability to complement human expertise and looks ahead with enthusiasm at the evolving landscape of generative AI.

Discover the transformative potential of digital twins in orthopedics and digital surgery in this enlightening episode.Dr. Steven Levine, from Dassault Systèmes, takes center stage to delve into the world of digital twins. Learn how his company employs 3D experiences and virtual human modeling to craft functional models of machines and devices. These virtual twins replicate real-world scenarios, aiding in predictive maintenance and failure prevention. The episode showcases the Living Heart Project, illustrating how the human organ's simulation helps understand its behavior under stress. The conversation also delves into digital twin technology's promising role in the medical realm, particularly in orthopedics. The importance of data collection from implants and the use of sensors to monitor performance takes the spotlight.Join us for this insightful episode and keep exploring our diverse collection!

Explore the revolutionary role of computer vision in healthcare through this engaging episode.Join us for an insightful interview with Douglas Fairbanks, the CEO of Advanced Scanners, as he sheds light on their pioneering technology designed for operating rooms. Douglas's extensive background in surgical intervention, technology, and commercialization underpins the discussion. Learn how their cutting-edge technology streamlines data collection, eliminating the need for manual intervention. The conversation also delves into the potential of artificial intelligence in the field and the intriguing challenges it poses for orthopedics.Tune in to discover more about the innovative solutions of Advanced Scanners and stay connected with Douglas for deeper insights!

Step into the spotlight with Edouard Saget from OrthoGrid in this captivating episode of the Digital Orthopedics Podcast. Edouard guides us through his remarkable journey of addressing a challenge in computer-assisted surgery and ingeniously fashioning a solution - a radiopaque grid that later evolved into a cutting-edge AI-driven concept. He emphasizes the elegance of simplicity in design and dives deep into their ongoing efforts, encompassing distortion resolution and the reduction of X-ray exposure in operating rooms. Their AI technology has undergone a transformative evolution, equipping surgeons with augmented insights during procedures, thus elevating accuracy and efficiency. This AI marvel is now trained to discern distinct surgical stages, offering real-time guidance to surgeons.Don't miss out on this riveting conversation, uncovering the groundbreaking ways in which this avant-garde AI technology is revolutionizing surgical procedures, making them more streamlined and economically viable.

Discover groundbreaking insights on regenerative drug candidates for knee osteoarthritis in this episode of the Digital Orthopedics Podcast with Dr. Denis Evseenko. Challenging the conventional view of interleukin six (IL-6) as solely pro-inflammatory, Dr. Evseenko unveils its potential role in tissue regeneration. Drawing from a study in Science Translational Medicine, he discusses the exciting implications for clinical outcomes and details his research on leveraging inflammation's regenerative potential to combat osteoarthritis. By selectively blocking the destructive facet of inflammation while nurturing the regenerative aspect, promising preclinical outcomes have been achieved.Stay tuned to witness the progression of this innovative approach through upcoming clinical trials, unlocking new horizons in osteoarthritis treatment.

Explore the realm of epigenomics through the insights of Dr. Stefano Bini's interview with Madalena Adorno, CEO of Dorian Therapeutics. Uncover Adorno's pioneering research on stem cells and aging biology, shedding light on the intricate interplay between senescent and stem cells in the context of aging and conditions like osteoarthritis. She also delves into her breakthrough studies on Down syndrome, revealing the identification of a key gene driving the aging phenotype.Tune in to learn how Dorian Therapeutics is pioneering a small molecule approach to USP 16 inhibition, offering promising avenues in the field of aging research.

Dive into the realm of Regenerative Medicine with insights from Fabrizio Billi, Lee Grossman, and Dr. Tobias Winkler as they dissect two significant clinical studies. Discover the outcomes of these studies: one spotlighting muscle regeneration through placental-derived cells, and the other delving into anti-inflammatory therapies for osteoarthritis treatment. While both studies present promising findings, challenges remain to be addressed. The discussion extends to the establishment of the Alliance for Advanced Therapies and Orthopedics, a pivotal initiative aiming to ensure quality standards in regenerative medicine and advanced therapies.Don't miss this episode as it unveils the optimistic potential within the medical horizon!

Explore the nuances of Value-Based Care, its challenges, and its advantages, particularly in orthopedics. Join Dr. Zeev Kain, Jon Warner, Marc Gruner, and Steven Schutzer as they dissect this subject, underscoring the importance of incentives and a gradual transition to this care approach. The consensus emerges that while physicians generally endorse value-based care, apprehensions and gaps in implementation exist. The discussion extends to data, technology's role in risk management, and the impact of AI on healthcare. The panel emphasizes collaboration, risk reduction, and scaling value-based models while reflecting on the potential of AI in healthcare.Tune in to gain insights into these experts' positive outlook on healthcare's future and the role of technology-driven advanced primary care!