It's a renaissance woman's world (Friends)

Our ol' friend, Brett Cannon, is back to talk all things Python. But first! Star Wars, Machete Order, Lost, Babylon 5, Game of Thrones, Murderbot, Ted Lasso, Project Hail Mary, David Attenborough, perpetual voice rights, and the AI uncanny valley.

Paul Dix joins us to discuss the InfluxDB co-founder's journey adapting to an agentic world. Paul sent his AI coding agents on various real-world side quests and shares all his findings: what's going to prod, what's not, and why he's (at least for a bit) back to coding by hand.

Mitchell Hashimoto's trust management system for open source, Nicholas Carlini has a team of Claudes build a C compiler, Stephan Schwab recounts the history of attempted developer replacement, NanClaw is an alternative to OpenClaw, and Sophie Koonin can't wrap her head around so many people going so hard on LLM-generated code.

Amal Hussein returns to tell us all about her new role at Istari, what life is like outside the web browser, how she's helping ambitious orgs in aerospace, what the SDLC looks like in 2026, and a whole lot more. Wait, moon vacuums?!

In May of 2025, Docker launched Hardened Images, a secure, minimal, production-ready set of images. In December, they made DHI freely available and open source to everyone who builds software. On this episode, we're joined by Tushar Jain, EVP of Engineering at Docker to learn all about it.

Jason Willems believes the tech monoculture is finally breaking, Don Ho shares some bad Notepad++ news, Tailscale's Avery Pennarun pens a great downtime apology, Milan Milanović explains why you can only code 4 hours per day, and Addy Osmani on managing comprehension debt when leaning on AI to code.

We discuss the buzz around Clawdbot / MoltBot / OpenClaw, how app subscriptions are turning into weekend hacking projects, why SaaS stocks are crashing on Wall Street, and what it all means.

As the creator and long-time maintainer of ESLint, Nicholas Zakas is well-positioned to criticize GitHub's recent response to npm's insecurity. He found the response insufficient, and has other ideas on how GitHub could secure npm better. On this episode, Nicholas details these ideas, paints a bleak picture of npm alternatives like JSR, and shares our frustration that such a critical piece of internet infrastructure feels neglected.

Clawdbot drives Mac Mini sales, Swizec Teller on the future of software engineering being SRE, Daniel Stenberg decided to end curl's bug bounty program, zerobrew takes some of the best ideas from uv and applies them to Homebrew, and Phil Eaton on LLMs and your career.

Techno Tim joins Adam to dive deep into the state of homelab'ing in 2026. Hardware is scarce and expensive due to the AI gold rush, but software has never been better. From unleashing Claude on your UDM Pro to building custom Proxmox CLIs, they explores how AI is transforming what's possible in the homelab. Tim declares 2026 the "Year of Self-Hosted Software" while Adam reveals his homelab's secret weapons: DNSHole (a Pi-hole replacement written in Rust) and PXM (a Proxmox automation CLI).