Alpha-Gal Syndrome: From Tick Bite to Anaphylaxis, Clinical Pearls and Unanswered

Alpha-gal syndrome has transformed our understanding of food allergy, linking tick bites to delayed anaphylaxis to mammalian meats. In this episode, we explore the epidemiology, immunologic mechanisms, diagnosis and management of alpha-gal syndrome with expert Scott Commins, MD, FAAAAI. Join us for practical clinical pearls and emerging insights into this unique disease.Continuing Medical Education credit is available with this episode. Visit here to complete the assessment and claim credit. .75 AMA PRA Category 1 Credit(s)™.Find out more about alpha-gal.

GLP-1 agonists have been blockbuster medications in diabetes and obesity but they may also have a surprising role in the treatment of asthma. Join the conversation as Katherine Cahill, MD, FAAAAI, discusses how GLP-1 agonists may improve asthma control and reduce airway inflammation.Find out more about asthma. 

AVaccines are a cornerstone of public health, training the immune system to prevent infectious diseases, especially in our most vulnerable patients. In this episode, John Kelso, MD, FAAAAI, reviews recent vaccine developments, including the importance of measles vaccination amid ongoing outbreaks, updates to vaccination schedules, considerations when using vaccines with biologics and evaluation of vaccine allergy. Join us for a practical review of key vaccine updates to help you protect your patients. Find out more about the importance of vaccinations across age groups. 

Improving access to penicillin allergy evaluation for millions of older patients would lead to better antibiotic treatment, decreased surgical site infections and fewer cases of C. diff. The Penicillin Allergy Verification and Evaluation Act has the potential to do just this. Priya Bansal, MD, FAAAAI, and Allison Ramsey, MD, FAAAAI, share their valuable insight into the Act and how we can make advocacy a part of our practice. Find out more about the Penicillin Allergy Verification and Evaluation Act

Julie Wang, MD, FAAAAI, shares highlights of the upcoming AAAAI Annual Meeting taking place in Philadelphia, Pennsylvania from February 27 to March 2. Listen in to hear what is in store this year as well as highlights such as the symposium on Philadelphia’s vaccine legacy as well as use of Artificial Intelligence and the new Practice Management Course. Visit the AAAAI Annual Meeting website.

As immunosuppressive therapies for cancer and autoimmune disease become more common, secondary immune deficiency is increasingly encountered in clinical practice. In this episode, Sara Barmettler, MD, FAAAAI, discusses the causes, diagnosis and management of secondary immune deficiency to help allergy and immunology physicians care for these patients effectively.

Join hereditary angioedema expert Aleena Banerji, MD, FAAAAI, for a discussion about the diagnosis and management of hereditary angioedema, focusing on treatment developments that have dramatically improved the care of patients with HAE.Continuing Medical Education credit is available with this episode. Visit here to complete the assessment and claim credit. .75 AMA PRA Category 1 Credit(s)™Find out more about hereditary angioedema.US Hereditary Angioedema Association 

Diagnosing Food Protein Induced Enterocolitis Syndrome (FPIES) can be challenging and once diagnosed, there are few options for treatment other than strict avoidance and waiting for resolution. Sara Anvari, MD, MSc, FAAAAI, discusses the presentation and pathophysiology of FPIES and how treatment options beyond avoidance are evolving.Continuing Medical Education credit is available with this episode. Visit here to complete the assessment and claim credit. .75 AMA PRA Category 1 Credit(s)™FPIES (Food Protein-Induced Enterocolitis Syndrome) Action Plan

How do families know when to give epinephrine and when to go to the ER? How long do we need to observe after an episode of anaphylaxis and who is at risk for recurrent symptoms? We discuss these important questions and more with Tim Dribin, MD, a pediatric emergency medicine physician, who is working to optimize emergency department care for patients with anaphylaxis.Learn more about anaphylaxis.

From now until December 31, 2025, AAAAI Fellows (those who have achieved the FAAAAI credential) and full members will select the next Board of Directors, including the next Secretary-Treasurer who will eventually ascend to become AAAAI President. Secretary-Treasurer candidates Stuart L. Abramson, MD, PhD, AE-C, FAAAAI, and Mariana C. Castells, MD, PhD, FAAAAI, offer their perspective on a series of questions pertaining to their candidacy during this must-listen episode. (November 3, 2025)Access the online voting center.