TWiV 1265: mRNA vaccines make cancer treatment great again

TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) J. Michael Bishop passes (NY Times) Vincent interviews JM Bishop (YouTube) David Botstein passes (NY Times) Post-attachment neutralization of HPV (npj vaccines) HPV vaccine blocks infection (Cancer Discov) Respiratory viral infections prime lung cancer growth (Cell) Respiratory virus infections awaken metastatic breast cancer (TWiV 1243 ) SARS-CoV-2 mRNA vaccines sensitize tumors to immunotherapy (TWiV 1265) Letters read  on TWiV 1309 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Project Hail Mary Rich – After a decade as a Yale hospital janitor, she is now a doctor there Alan – Scientific analysis of jokes in conference talks Vincent – Yuval Noah Harari: Why advanced societies fall for mass delusion Listener Pick Greg – Changes in Terrestrial N Budgets and Riverine Nitrate-N Yields from Mississippi River Basin Watersheds 2000 to 2020 Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, safety data of the RSV vaccine for high risk young adults, recognition of unrecognized COVID-19 deaths (but weren’t we not allow to call it a COVID-19 in 2020?), retraction of and how the ANTIBIOTIC azithromycin is NOT an antiviral drug, how to access and pay for Paxlovid, long COVID patients with neurocognitive symptoms and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Confusion abounds over future of US vaccine advisory committee (The Guardian) Key Adviser Quits Federal Vaccine Panel (NY Times) Vaccinate the vacca? …..Why We Must Vaccinate US Dairy Cattle Against HPAI H5N1(JID) Largest Animal Health Emergency in US History Continues as HPAI Hits Indiana Hard (Hoosier AG Today) Indiana: More than 350,000 birds killed in massive avian flu outbreak (CIDRAP) 5 children receive E. Coli from raw milk; TN dairy farm responds (Local 3 News) Quick takes: Measles spike in Utah, 5 kids ill from raw milk, CDC director uncertainty (CIDRAP) Increasing Predominance of Norovirus GII.17 over GII.4, United States, 2022–2025 (Emerging Infectious Diseases) Wastewater for norovirus (WasterWater Scan) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) Weekly surveillance report: clift notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) Immunogenicity and Safety of the AS01E-adjuvanted Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine in Adults Aged 18–49 Years at Increased Risk of RSV Disease Compared with Adults Aged ≥60 Years  (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study (PLoS Medicine) Applying machine learning to identify unrecognized COVID-19 deaths recorded as other causes of death in the United States (Science Advances) RETRACTED work: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial (International Journal of Antimicrobial Agents) Antibiotic used in COVID patients tied to increased signs of antibiotic resistance (CIDRAP) Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 (Nature Microbiology) COVID-19 mRNA Vaccination in Pregnancy and Risk of Infection in Early Childhood (Pediatrics) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Outcomes of Patients with Neurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine) Outcomes of Patients withNeurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine) Long COVID Treatment Guide (rthm) Reaching out to US house representative Letters read on TWiV 1308 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected] Content in this podcast should not be construed as medical advice.

TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Robin Weiss passes (ICR) Judge strikes down RFK Jr.’s vaccine policies (NYTimes) How Rep protein packages AAV DNA (Cell Rep) How influenza virus causes heart damage (Immunity) Influenza virus hitches a cellular ride to the heart (Cell Host Microbe) Letters read  on TWiV 1307 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – The math of March Madness brackets Kathy – SpaceX launch plume, jellyfish APOD and Cleveland Meteor, map of meteorites fall and a doorbell cam photo Rich – After barista’s tips were stolen, strangers showed up with $900 Vincent – What Causes Gravitational Time Dilation? A Physical Explanation. Listener Pick Charles – They’re Made Out Of Meat Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, ‘renaming’ of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, expansion of the RSV vaccine licensure to include high risk yound adults, association between lung cancer and respiratory illnesses, how to access and pay for Paxlovid, effectiveness of vaccination or supplemental vitamin D to reduce the risk of long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Local waterfowl die-off likely caused by bird flu (The Suffolk Times) East End officials respond as dead birds pile up on Long Island shorelines (news 12: Long Island) FDA Adverse Event Monitoring System(AEMS)(FDA) FDA Launches NewAdverse Event Look-Up Tool(FDA) FDA announces AEMS, new adverse-event database to replace VAERS (CIDRAP) US cuts broad recommendation for four childhood vaccines including flu (Reuters) US CDC deploys staff to curb South Carolina’s measles outbreak (Reuters) US judge upends Kennedy’s overhaul of childhood vaccine policies (Reuters) American Academy of Pediatrics, et al v. Robert F Kennedy, Jr, et al (Civil Action No 25-11916-BEM) White House Puts RFK Jr.’s HHS on Tighter Leash After MAHA Setbacks(Wall Street Journal) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) Weekly surveillance report: clift notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) FDA expands approval for RSV vaccine to include younger adults at high risk (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) 2024–2025 COVID-19 mRNA Vaccine Effectiveness Against Severe Disease (JID) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods (CID) A Randomized Trial of Vitamin D Supplementation and COVID-19 Clinical Outcomes and Long COVID: The Vitamin D for COVID-19 Trial (The Journal of Nutrition) Long COVID Treatment Guide (rthm) Reaching out to US house representative Letters read on TWiV 1306 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected] Content in this podcast should not be construed as medical advice.

TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) IgNobel Prize ceremony moved to Europe (Science) Prasad is out of the FDA (again) (npr) Sunshine virus in carpet pythons (J Virol) Selection preceding epidemics and pandemics (Cell) Letter read on TWiV 1305 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Galileo’s handwritten notes found in ancient astronomy text Rich – Dungeon Crawler Carl by Matt Dinniman Alan – High-resolution 3D imaging of the USS Monitor by NOAA’s new µSAS system Vincent – The Order of Time by Carlo Rovelli Listener Pick Douglas – Grandparents for vaccines Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the ‘eradicated’ poliovirus, the suggestion of RFK’s autocratic ability to change vaccine policy and the ‘resignation’ for the second time of CBER director Vinjay Prasad, and zoonotic spillover of viruses without adaptation, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, VRPBEC meeting for ‘flu’ vaccine strain selection, how to access and pay for Paxlovid, closing of long COVID treatment centers globally, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Polio: Practice enhanced precautions…..but isn’t it eradicated? (CDC: Travelers’ Health) RFK Jr has ‘unreviewable‘ authority to reshape vaccine policy, DOJ lawyer tells judge….’unreviewable’ is not even a word! (Reuters) Stark Divide: Americans More Confident in Career Scientists at U.S. Health Agencies Than Leaders (Annenberg: Public Policy Center, University of Pennsylvania) Divisive F.D.A. Vaccine Regulator Is Resigning…..for the second time in 6 months (NY Times) Characteristics and Outcomes of Patients With Hematologic Malignancies Hospitalized With Respiratory Viral Infections (OFID) Dynamics of natural selection preceding human viral epidemics and pandemics (Cell) Recent pandemic viruses, including SAR-CoV-2, spread directly to people without adaptation, researchers say (CIDRAP) Wastewater for measles (WasterWater Scan) US CDC deploys staff to curb South Carolina’s measles outbreak (Reuters) Measles cases and outbreaks (CDC Rubeola) Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) Effectiveness of RSV Vaccines against RSV-Associated Thromboembolic Events (CDC: Emerging Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Characteristics of Young Children Hospitalized With Acute Respiratory Failure From Infection With Respiratory Syncytial Virus, SARS-CoV-2, or Both, November 2023–March 2024 (OFID) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Where are the long COVID clinics? (ScienceNews) Left without care: Many Long COVID clinics are closing down in the U.K. (The Sick Times) Where have all the Long COVID clinics gone? (The Sick Times) Reaching out to US house representative Letters read on TWiV 1304 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected] Content in this podcast should not be construed as medical advice.

TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Shingles vaccination may slow biological aging (J Gerontol) Getting virus classification and nomenclature right (J Virol) Mucosal vaccination blocks diverse respiratory diseases (Science) Timestamps by Jolene Ramsey. Thanks!   Weekly Picks Brianne – I grew up unvaccinated. Now I’m an Immunologist Rich – Horizons from PBS News – The science behind exercise and why it’s good for our bodies; The London Busman Study (Cardiac Health) Alan – Waste Wars: The Wild Afterlife of Your Trash, by Alexander Clapp Vincent – America vs the World by Robert Kagan Listener Pick Anne – Winners of the 2026 Underwater Photographer of the Year Award Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal population before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolinaand Utah, ICE detention centers, lack of accurate reporting may prevent the US from losing its status as a country that eliminated measles, immune amnesia from measles infection, influenza strain selection for the 2026-2027 vaccine,  recent statistics for RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, clinical trials for long COVID treatment including GLP-1 inhibitors and IVIG and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Kristen Panthagani, MD, PhD (Substack) You can know things! (Substack) Kmpanthagani: Kristen Panthagani, MD, PhD Instagram) Kristen Panthagani, MD, PhD kmpanthagani (Threads) Psychological inoculation improves resilience against misinformation on social media (Science) 5 Logical fallacies in the era of RFK Jr. (Substack) Tecovirimat for the Treatment of Mpox (NEJM) California records avian flu in northern elephant seals (CIDRAP) First Cases of Highly Pathogenic Avian Influenza in Northern Elephant Seals Confirmed in California (UC Davis) Wastewater for measles (WasterWater Scan) The health and economic repercussions of declining MMR coverage in the United States (medRxiv) 2025 measles resurgence carries estimated $244 million price tag (CIDRAP) US builds case to retain measles elimination status as infections mount (Reuters) Expert meeting on US measles elimination status delayed to November (Reuters) ‘Nearly Every’ Child With Measles Suffers This Hidden Threat (Medscape) CDC acting director Bhattacharya urges use of measles vaccine (Reuters) Measles cases and outbreaks (CDC Rubeola) Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Escobar: ICE sending sick migrants to El Paso hospitals for quarantine (BorderReport) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) RSV Detection and Antibiotic Prescribing Decisions for Pediatric Respiratory Tract Infections (JAMA Network) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2Persistence and the Gut Microbiota: New Insights into Long COVID Pathogenesis (MDPI) Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 (Annals of Internal Medicine) Long COVID: RECOVER-TLC Clinical Trials (Foundation for the National Institute of Health) Design and rationale of RECOVER-AUTONOMIC: A randomized platform trial evaluating interventions for Long COVID postural orthostatic tachycardia syndrome (American Heart Journal) Dr. Ruth’s Newsletter: COVID, Flu & Health News, 3/1/26 (Substack) Reaching out to US house representative Letters read on TWiV 1302 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected] Content in this podcast should not be construed as medical advice.

TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) LCMV seroprevalence among pregnant women (Emerg Inf Dis) Giant viruses encode functional vIF4F (Cell) Ribosomal proteins encoded in viral genomes (virology blog) Letters read on TWiV 1301 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – “The Song of the Cell” by Siddhartha Mukherjee. Kathy – Fitbit for farts (WSJ and 1° article) Rich – The Password That Lets Caterpillars Hide in an Ant’s Lair Vincent – Astrophysics for People in a Hurry by Neil deGrasse Tyson Listener Pick Larry – Get an early start! (primary article) Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode States vs RFK Jr and Bhattacharya: changes to the childhood vaccine schedule (Office of the Attorney General, California) Surgeon General Nominee Sidesteps Questions on Vaccines at Senate Hearing (NY Times) Unqualified failure in polio vaccine policy left thousands of kids paralyzed (Science) Clinical and Epidemiological Investigation of Vaccine-Derived Poliovirus Type 2 Outbreak in Pakistan During 2019–2021 (CID) Inactivated Polio Vaccine Must Be an Essential Part of Polio Eradication (CID) Wastewater for Candida auris: Wastewater (WasterWater Scan) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium (eClinical Medicine) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1300 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected] Content in this podcast should not be construed as medical advice.