Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
#423: Zoya Huschtscha, PhD – Understanding Sarcopenia & Potential Interventions
36:25Zoya Huschtscha, PhD is a researcher and assistant lecturer at Monash University (Australia), in the Department of Nutrition and Dietetics. She completed her PhD at the same institution, where her research focused on interventions to prevent and treat sarcopenia; i.e. the loss of muscle function and mass, typically with age. Zoya also has a Masters of Dietetics. In addition to her academic work, she works in private practice as a sports dietitian. Show notes available at sigmanutrition.com/episode423/
#422: Psychobiotics – Can Probiotics Improve Mood-related Disorders?
1:04:09and the Sigma Statement on the gut-brain axis can be found at " data-userid="424351203778215936" data-orgid="425311536639447040">In this episode the Sigma team discuss the research looking at 'psychobiotics'; i.e. probiotics that have health impacts on those with pyschiatric disorders or symptoms. They discuss the origins of the research, the gut-brain axis, mechanisms by which gut microbiota could impact mood, and then the human trials to date that have examined probiotics' effects on mood, anxiety, depression, bipolar disorder and other outcomes. and the Sigma Statement on the gut-brain axis can be found at " data-userid="424351203778215936" data-orgid= "425311536639447040">Show notes can be found at sigmanutrition.com/episode422/ and the Sigma Statement on the gut-brain axis can be found at sigmanutrition.com/gut-brain-axis/
#421: Brendon Stubbs, PhD – The Research on Depression & Physical Activity
1:00:43Dr. Brendon Stubbs, PhD, is a Senior Clinical Lecturer and researcher at King's College London, conducting research in physical activity & mental health, the mind-body interface, and meta-research. He has published over 600 academic papers in several leading journals across multiple scientific fields. He has informed policy guidelines in the UK, Europe and the World Health Organization. Dr. Stubbs is also a clinical physiotherapist, being Head of Physiotherapy at the South London and Maudsley NHS Foundation Trust. He has a MSc in Neurological Rehabilitation & PhD in Pain Medicine & Rehabilitation. Show notes to this episode are available at sigmanutrition.com/episode421/
#420: Cannabis – Kevin Boehnke, PhD & Carrie Cuttler, PhD
1:21:02Kevin Boehnke is a researcher at the University of Michigan, in the Chronic Pain and Fatigue Research Center. His current research focuses on therapeutic applications of illicit or semi-licit substances (cannabis, psychedelics). His goal is to rigorously assess appropriate use of these substances and to help address the public health harms caused by their criminalization. Carrie Cuttler is an Assistant Professor at Washington State University. Her research at the Health and Cognition Laboratory there focuses on elucidating the potentially beneficial and detrimental effects of chronic cannabis use and acute cannabis intoxication. Her recent work has focused on examining links between cannabis use and mental health (e.g., ADHD, PTSD, OCD, depression, anxiety). Show notes available at sigmanutrition.com/episode420/
A New Year Message For Our Listeners
4:47Wishing all the Sigma audience a great 2022!
#419: Nathan Bryan, PhD – Role of Nitric Oxide in Human Health
39:21Dr. Nathan Bryan, PhD is an Adjunct Assistant Professor at Baylor College of Medicine. Dr. Bryan has been involved in nitric oxide research for the past 18 years and has made many seminal discoveries in the field. He was the first to demonstrate and discover an endocrine function of nitric oxide via the formation of S-nitrosoglutathione and inorganic nitrite. Dr. Bryan obtained his doctoral degree from Louisiana State University School of Medicine in Shreveport where he was the recipient of the Dean’s Award for Excellence in Research. He pursued his post-doctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute. After a two year post-doctoral fellowship, in 2006 Dr. Bryan was recruited to join faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology. Show notes at sigmanutrition.com/episode419/
#418: Should We Consume a Direct Source of DHA?
1:17:44In this episode Danny and Alan discuss the debate around whether a direct source of the long-chain omega-3 fatty acid DHA should be recommended. Many people do not consume the marine foods (primarily fatty fish) that contain DHA, and higher DHA intakes, DHA status, and omega-3 indices are predictive of certain health outcomes. But the essential omega-3 fatty acid alpha-linolenic acid (ALA) can be consumed from plant sources. So do those who do not consume direct sources of DHA have lower DHA status? Does this matter? And if so, then what pragmatic conclusions can we come to? All of this is covered in this episode. Show notes available at sigmanutrition.com/episode418/
#417: Austin Baraki, MD – What Do Nutrient Blood Tests Actually Tell Us?: Understanding Biomarkers
1:03:25Dr. Austin Baraki joins Danny and Alan to critically evaluate the assumption that blood levels of a nutrient directly tell us about overall nutritional status. With many people getting blood tests done outside of clinical settings, there is significant risk of misinterpretation of what these measures mean. In this episode we discuss measures of calcium, sodium, vitamin D and others as examples of where misinterpretation and misunderstanding can happen. Show notes can be found at sigmanutrition.com/episode417/
#416: David Nunan, PhD – Evidence-Informed Health Care: Evidence-based Medicine 2.0
48:40Dr. David Nunan, PhD is a Lecturer and Senior Research Fellow in the Centre for Evidence-Based Medicine at the University of Oxford. There, he is the Director of the Postgraduate Certificate in 'Teaching Evidence-Based Health Care' and the lead tutor for the internationally-renowned 'Teaching Evidence-Based Medicine' course. He is a principal investigator with research interests in prevention and treatment of lifestyle-related conditions, improving the understanding and use of research evidence, and meta-epidemiology (research on research). David has experience in a breadth of methodologies including diagnostic studies, statistical analysis, qualitative research and clinical trials. Show notes available at sigmanutrition.com/episode416
#415: Prof. Bruce Neal – Can Salt Substitutes Reduce Cardiac Events & Death?
46:24Bruce Neal is Executive Director at The George Institute for Global Health Australia; and Professor of Medicine, UNSW Sydney. Prof Neal is a UK-trained physician who has 25 years’ experience in clinical, epidemiological, and public health research with a focus on heart disease, stroke and diabetes. Bruce has a longstanding interest in high blood pressure and diabetes and the potential for both clinical interventions and changes in the food supply to deliver health gains. His work has been characterised by its focus on collaboration, quantitation, translation and impact. He holds professorial appointments at UNSW Sydney, Imperial College London, and an honorary appointment at the University of Sydney. He has published some 450 scientific papers and since 2016 has been identified by Thomson Reuters as one of ‘The World’s Most Influential Scientific Minds’, an acknowledgement provided to just a few thousand researchers across all disciplines, worldwide. He has particular expertise in the conduct of large-scale clinical trials addressing cardiovascular disease but has also done a significant body of work addressing food policy issues related to sugars, fats, portion size and food labelling. Find the show notes at sigmanutrition.com/episode415/