Conavi Medical Unveils Next-Gen Dual-Modality Catheter for Cardiac Interventions

Tonix Pharmaceuticals CEO Dr. Seth Lederman joined Steve Darling from Proactive to announce an important milestone for the company’s New Drug Application (NDA) for a novel fibromyalgia treatment. The U.S. Food and Drug Administration (FDA) has set a Prescription Drug User Fee Act (PDUFA) goal date of August 15, 2025, marking the anticipated timeline for a decision on marketing approval. The treatment is a non-opioid, centrally acting therapy designed to address fibromyalgia, a chronic and debilitating pain condition that disproportionately affects women and impacts over 10 million adults in the United States. Highlighting the significance of the FDA collaboration, Dr. Lederman stated, “We believe this therapy has the potential to become the first in a new class of medicines for managing fibromyalgia.” Data from pivotal Phase 3 trials demonstrated meaningful pain reduction with a favorable safety profile, addressing an urgent unmet need in the fibromyalgia patient community. The NDA submission is supported by data from two 14-week, double-blind, randomized, placebo-controlled Phase 3 clinical trials, which confirmed the treatment's efficacy and tolerability with no new safety concerns. Previously granted Fast Track designation by the FDA in July 2024, the therapy is recognized for its potential to transform the fibromyalgia treatment landscape. If approved, this innovative therapy would be the first new drug for fibromyalgia in more than 15 years, offering hope to millions of patients seeking effective and tolerable treatment options. #proactiveinvestors #tonixpharmaceuticalsholdingcorp #nasdaq #tnxp #FibromyalgiaTreatment #FDAApproval #TNX102SL #NonOpiateTherapy #PharmaNews #DrugDevelopment #ProactiveInvestors#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Hive Digital Technologies Executive Chairman Frank Holmes joined Steve Darling from Proactive to shared significant updates with Proactive, announcing the acquisition and deployment of NVIDIA H100 GPUs and the latest NVIDIA H200 GPUs. The company has invested $30 million into these cutting-edge supercomputing clusters, reinforcing its position as a leader in high-performance computing (HPC) and artificial intelligence (AI). The NVIDIA H200 cluster, consisting of 508 GPUs across 64 nodes connected via Infiniband, has been shipped and is set to arrive in Quebec in early January 2025. Deployment and customer access are planned for Q1 2025, leveraging Quebec’s 100% renewable energy infrastructure to align with Hive’s sustainability mission. Holmes emphasized that the new supercomputing clusters will unlock significant revenue opportunities, enabling Hive to meet the growing global demand for AI computing power. The company projects an annualized run-rate revenue of over $20 million by Q2 2025 from its HPC services, focusing on high-margin applications such as AI model training and cloud computing services. This strategic expansion highlights Hive’s pivot toward diversifying its operations to capitalize on the booming AI market while continuing its Bitcoin mining activities. Holmes noted, "Our investments underscore our commitment to sustainability, innovation, and positioning Hive as a key player in the gig economy and digital transformation." #proactiveinvestors #hivedigitaltechnologieslet #tsxv #hive #nasdaq #hive #NvidiaGPUs #AIChips #TechInvestment #HighPerformanceComputing #AIInfrastructure HealthcareAI #AIForGood #FutureOfTech #DigitalTransformation #AI #ArtificialIntelligence #DigitalEconomy #GigEconomy #DataCenters #TechInnovation #HiveDigitalTechnologies #GreenEnergy #SustainableTech #AIRevolution #QuebecDataCenters#investment #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Blockmate Ventures CEO Justin Rosenberg joined Steve Darling from Proactive to announce the company’s latest achievement: the closing of a $1.4 million strategic investment from a group of investors led by renowned innovation leader and visionary investor Antanas Guoga. This significant funding will help accelerate the growth and expansion of Blockmate's portfolio, positioning the company for greater success in its next phase of development. Rosenberg emphasized that Hivello Holdings Ltd, Blockmate's primary asset, has already been able to secure capital independently since December 2023, demonstrating the strong market interest in its business. However, this new infusion of capital will specifically focus on driving forward the launch and growth of Blockmate's subsequent portfolio companies, marking a pivotal moment in the company’s strategic evolution. Guoga, widely recognized for his leadership in technological innovation, is the chairman and major shareholder of Sol Strategies Inc., a Canadian holding company established to invest in breakthrough technologies, including blockchain and cryptocurrencies. His deep expertise in both emerging technologies and the global investment landscape will be invaluable as Blockmate continues to build its portfolio of companies. As a former Member of the European Parliament, Guoga has been a champion for digital and technological advancement. His advocacy for blockchain applications and his extensive influence across both private and public sectors align strongly with Blockmate’s mission. “Tony G’s commitment to driving blockchain applications with social impact makes his investment a powerful endorsement of our vision,” Rosenberg shared with Proactive. This strategic investment further solidifies Blockmate Ventures as a key player in the growing blockchain and technology space, with a strong focus on social impact and technological innovation. With Guoga’s expertise and global network backing its growth, Blockmate is poised to make significant strides in its expansion plans. #Hivello #DePIN #Blockchain #Crypto #cve #mate #PassiveIncome #Web3 #Bitcoin #ZuluPartnership #TechInnovation #ProactiveInvestors #ProactiveInvestors #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews #BlockchainInvestment #Crypto2025 #TonyGuoga #PassiveIncome #CryptoGrowth #Hivello #DigitalInfrastructure #BlockchainTechnology #investment #investor #stockmarket #stocks #stock #stockmarketnews

Seeing Machines Ltd (AIM:SEE, OTC:SEEMF) CEO Paul McGlone talked with Proactive’s Tylah Tully about the company’s groundbreaking collaboration with Mitsubishi Electric Mobility Corporation. Mitsubishi now holds a 19.9% stake in Seeing Machines, following a strategic agreement. McGlone highlighted how this partnership enhanced the company’s balance sheet and supported expansion in Japan's automotive market, with a focus on leveraging Mitsubishi's global distribution network. Key details include Seeing Machines' plans to distribute its Guardian Generation 3 product through Mitsubishi's US network and beyond. Additionally, McGlone outlined potential growth in new verticals such as factory automation and public utilities, thanks to Mitsubishi's diverse expertise. Despite this partnership, Seeing Machines remains committed to other collaborations. McGlone reaffirmed the company's primary goal of achieving a cash flow breakeven run rate by the end of the fiscal year and moving toward profitability. He emphasised that this investment alleviated shareholder concerns about financial stability. #ProactiveInvestors #SeeingMachines #MitsubishiInvestment #AutomotiveInnovation #GlobalPartnership #CashFlowBreakEven #TechInvestment #BusinessGrowth #VehicleSafety #ProactiveInvestors #TechCollaboration

Midnight Sun Mining Corp Director of Marketing and Communications Adrian O’Brien joined Steve Darling from Proactive to shared exciting developments with Proactive regarding the company's flagship Kazhiba Target. The Mining Licensing Committee recently approved the renewal application for a Large-Scale Exploration License, resolving prior concerns surrounding the Kazhiba Project’s license status. O’Brien emphasized that the approval solidifies the foundation for Midnight Sun’s exploration and development activities, clearing the way for near-term milestones. The company is now focused on completing and analyzing the results of its exploration program at Kazhiba. This work is being carried out in collaboration with First Quantum Minerals as part of a broader campaign to identify near-surface oxide copper mineralization. The target is to supply Africa’s largest copper mining complex, Kansanshi, located just a few kilometers away. This strategic approach provides Midnight Sun with potential near-term production and cash flow, offering a rare, non-dilutive funding path to further explore its underlying sulfide copper targets at Kazhiba, Mitu, and Crunch. Additionally, Midnight Sun and KoBold Metals have agreed to amend their earn-in agreement, removing the longstop date to allow additional time for securing the necessary Zambian regulatory approvals to finalize the agreement. This amendment underscores the commitment of both parties to the project's success and positions Midnight Sun to capitalize on its promising exploration portfolio. #proactiveinvestors #midnightsunminingcorp #tsxv #mma #otc #mdngf #mining #MiningNews #ZambiaMining #KazhibaLicense #MidnightSunMining #CopperProduction #FirstQuantum #MineralExploration #ProactiveInvestors #SustainableMining #investment #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Fineqia International Analyst Matteo Greco joined Steve Darling from Proactive to share insight regarding the company's analysis of global Exchange Traded Products with digital assets as collateral. The findings revealed that Assets Under Management for these products reached a historic $150 billion in November, a more than threefold increase from $49.5 billion at the start of 2024. This growth was bolstered by market optimism surrounding U.S. presidential election results. The company said ETP AUM grew 202.6% year-to-date, far outpacing the broader digital asset market. It rose by 49.2% in November alone, breaking the previous $100.5 billion record set in October. Bitcoin ETPs led the charge, with their AUM jumping 49.6% in November to $124.4 billion, driven by a 37.2% increase in BTC’s price, which reached $96,485. The digital asset market surpassed its November 2021 high, reaching a total market capitalization of $3.57 trillion, a 40.7% increase from $2.54 trillion in October. Year-to-date, the market capitalization more than doubled from $1.77 trillion at the end of 2023. For the first time, Ethereum spot ETFs recorded positive cumulative net flows, with November net inflows of $1.1 billion, bringing total net inflows to $573 million since inception. Greco noted that ETPs, including Exchange Traded Funds and Exchange Traded Notes, continue to attract significant investor interest, further cementing their role as a key vehicle for accessing the digital asset market. This growth reflects increasing institutional and retail demand for secure and accessible exposure to cryptocurrencies. Looking ahead to 2025, Greco expressed optimism about the sector's potential, citing supportive market trends and technological adoption. He added that simplified access through financial products like ETPs is helping bridge the gap between traditional and digital finance. #proactiveinvestors #fineqiainternationalinc #cse #fnq #otc #fnqqf #CryptocurrencyMarket #FinancialInnovation #AssetManagement #InstitutionalInvestment #CryptoGrowth #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Ocean Power Technologies CEO Philipp Stratmann joined Steve Darling from Proactive to share news regarding the company's progress on its innovative PowerBuoy system for the Naval Postgraduate School. The primary assembly of the PowerBuoy, equipped with AT&T® 5G technology and advanced subsea sensors, is now complete. Integration of OPT’s Merrows suite, which offers AI-driven Maritime Domain Awareness, has also been finalized. The system is being prepared for shipment, with deployment slated for early 2025. It will coincide with the Technology Showcase hosted by NPS in January, marking a significant milestone for OPT’s strategic initiatives. Once operational, the PowerBuoy will deliver continuous, autonomous monitoring and data collection capabilities in a critical maritime region. According to Stratmann, this deployment underscores OPT's strategic plan and ability to scale cutting-edge solutions. He added, “This project demonstrates the capability of PowerBuoys to serve as 5G communication nodes across U.S. coastlines.” This collaboration with NPS highlights OPT's role in advancing maritime technology and supporting strategic defense and communication initiatives in key maritime zones. #proactiveinvestors #oceanpowertechnologiesinc #nyseamerican #optt #PhillipStratmann, #USGovernmentContract, #OffshoreAutonomy, #MaritimeSecurity, #CommercialPlatforms, #GrowthStrategy, #BuoyBusiness, #VehicleBusiness, #InternationalExpansion, #ReadyToDeploy #RenewableEnergy #PowerBouy #CleanEnergy #5GInnovation #SustainableTechnology #MaritimeSolutions #EnergyInnovation #ProactiveNews #PhilippStratmann#investment #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Giyani Metals Corp (TSX-V:EMM, OTC:CATPF) CEO Charles FitzRoy talked with Proactive's Stephen Gunnion about the commissioning progress of the company's demonstration plant in Johannesburg. While the company is targeting the first production of high-purity manganese sulphate monohydrate by year-end, unforeseen setbacks like power and water outages have caused potential delays into early Q1. FitzRoy highlighted the plant's role in de-risking the main facility planned for Botswana and noted minor adjustments that improve operational insights. "The demonstration plant is multifaceted," FitzRoy explained. It serves to mitigate risks, refine processes, and train staff for the commercial facility, alongside facilitating R&D for various battery chemistries. He also touched on global market trends, emphasising the increasing role of manganese in EV batteries, particularly within different regional preferences. Despite challenges, FitzRoy affirmed Giyani's commitment to the timeline and recognised shareholders' anticipation of progress. He stated the team is working diligently, even through the festive period, to achieve its goals. For more updates and insights, visit Proactive’s YouTube channel. Don’t forget to give the video a like, subscribe to the channel, and enable notifications for future content! #GiyaniMetals #Manganese #EVBatteries #MiningInnovation #BatteryTech #SustainableEnergy #DemonstrationPlant #HighPurityManganese #CleanEnergy #Investing#ProactiveInvestors#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Kodal Minerals PLC (AIM:KOD) CEO Bernard Aylward talked with Proactive's Stephen Gunnion about the company’s significant progress at its Bougouni lithium project in Mali. Aylward shared updates on developments at the Ngoualana open pit mine and ongoing site enhancements. He emphasised that mining activities are ahead of schedule, with substantial materials already stockpiled for processing. The company is preparing for production in the first quarter of 2024, with the DMS and flotation plants nearing completion. Aylward also highlighted exploration efforts at the Boumou deposit, focusing on resource expansion and metallurgical testing. “We expect our shareholders will see first-quarter production trucks rolling out,” Aylward noted, expressing confidence in the upcoming milestones. Stay tuned for more updates as Kodal Minerals progresses toward its ambitious targets in the lithium sector. Visit Proactive's YouTube channel for more videos, and don’t forget to like this video, subscribe to the channel, and enable notifications for future updates. #KodalMinerals #LithiumMining #BougouniProject #MiningUpdates #MaliLithium #BatteryMetals #ResourceDevelopment #CEOInterview #ProactiveInvestors #lithiumStocks #ProactiveInvestors#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Cyprium Metals Ltd (ASX:CYM, OTC:CYPMF). The company plans to conclude 2024 with a $3 million non-renounceable entitlement offer following a two-tranche placement that raised approximately $13.5 million. The entitlement offer provides one new share for every 16 existing shares held as of December 30, 2024, priced at $0.028 per share, along with one unquoted option for every two new shares subscribed. Up to 106.98 million new shares and 53.49 million options may be issued. The funds will support the restart of the Nifty Copper Mine in Western Australia and will be used for site costs, permitting support, definitive feasibility study preparations, tenement maintenance, geological work and financing obligations tied to Cyprium’s MLX convertible notes and Glencore facility. Combined with the placement and surplus equipment sales, the company expects to generate $23 million in gross proceeds, ensuring financial stability to advance its plans. The company highlighted 2024 as a "transformational year," achieving key technical and financial milestones. The entitlement offer allows all shareholders to invest on the same terms as insider and institutional subscribers. #ProactiveInvestors #CypriumMetals #ASX #OTC #NiftyCopperMine #CopperMining #ASXStocks #EntitlementOffer #MiningInvestment #FinancialMilestones #MineralExploration #DFSPreparation #GeologicalWork #LoanFacility #MiningAustralia #OperationalFunds #Transformational2024 #ShareholderValue #ResourceDevelopment #ConvertibleNotes #GlencoreFacility #InstitutionalInvestors #FinancialStrategy