Dr. Helen Messier on AI, Epigenetics & the Future of Aging | SNH Podcast #165

In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Jodi Duval, Dr. Allen Bookatz, and Dr. Ted Achacoso as they explore the future of clinical intelligence — and why medicine must move beyond single biomarkers to understanding networks within the body. Rather than chasing isolated lab values like glucose, cholesterol, or testosterone, the conversation shifts toward a systems-based approach — where every biomarker is part of a dynamic network of relationships. From metabolomics to hormone balance, this episode explains why optimizing health requires understanding how different systems interact, adapt, and influence each other in real time. Join us as we delve into: Why single biomarkers are only "nodes" in a larger biological network The concept of nodes and edges in human physiology How glucose, thyroid, and metabolic systems are interconnected Why cholesterol, inflammation, and B vitamins must be viewed together The risks of optimizing one biomarker (like testosterone) in isolation This episode is for you if: You've been told to "fix" a single lab value but still feel off You want to understand your lab results in a deeper, systems-based way You're a practitioner looking to move beyond reductionist medicine You're interested in metabolomics and the future of health optimization You can also find this episode on… Youtube: https://youtu.be/CMbdZEnnuGo Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026:https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://www.homehope.org/ Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://www.troscriptions.com/  

In this episode of the Health Optimization Medicine Podcast, join Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore the hidden cost of convenience and comfort in modern life.   From ultra-processed foods and low-fiber diets to sedentary lifestyles and technology-driven comfort, the conversation dives into how convenience is quietly reshaping our biology. The HOMeHOPe Faculty explains why small daily habits — like eating whole foods, moving regularly, and embracing mild discomfort — are essential for maintaining cellular health and resilience.   Rather than trying to "hack" health with quick fixes, the discussion emphasizes consistent lifestyle behaviors that support the microbiome, metabolic function, and long-term health optimization.   Join us as we delve into: • Why fiber is the fastest disappearing macronutrient in modern diets • The role of gut microbiota and short-chain fatty acids in health • Why habits like sleep, eating, and exercise cannot be "banked" • The physiological consequences of ultra-convenient lifestyles • Practical ways to introduce beneficial stress back into daily life   This episode is for you if: • You want to understand how convenience affects human physiology • You're interested in the role of fiber and gut health in disease prevention • You want practical ways to improve resilience and metabolic health • You're curious about the philosophy behind Health Optimization Medicine   You can also find this episode on… YouTube: https://youtu.be/6wLPUuLQgcY   Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://www.homehope.org/   Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://www.troscriptions.com/

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the core philosophical framework behind Health Optimization Medicine. Dr. Scott Sherr, Boomer Anderson, and Dr. Allen Bookatz break down the three fundamental perspective shifts that redefine how we think about health, disease, aging, and the human body itself. Rather than focusing on disease management, this episode introduces the foundational principles behind building health from the cellular level up. Join us as we delve into: • The shift from pathogenesis (studying disease) to salutogenesis (creating health) • Why longevity alone isn't enough without vitality and morbidity compression • How neotenization focuses on restoring youthful biological function • The concept of the holobiont: humans as ecosystems of interconnected organisms This episode is for you if: • You want to understand the philosophy behind Health Optimization Medicine • You're curious why modern healthcare focuses on disease instead of health • You're interested in metabolomics, cellular health, and systems biology • You want a deeper framework for longevity, vitality, and resilience You can also find this episode on… Youtube: https://youtu.be/wuCXmT783_o Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026:https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://www.homehope.org/ Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://www.troscriptions.com/

In this episode of the Smarter Not Harder Podcast, Dr. Helen Messier joins Dr. Scott Sherr for a wide-ranging and thought-provoking conversation about longevity, epigenetics, AI-powered medicine, and the real meaning of healthspan. From whole genome sequencing to digital twins and emotional resilience, this episode bridges cutting-edge science with deeply human healing in a way that challenges how we think about aging. Join us as we delve into: The difference between lifespan and healthspan — and why resilience matters more than years Whole genome sequencing, polygenic risk scores, and the limits of genetic hype Multi-omics medicine: genomics, metabolomics, proteomics, and systems biology AI in healthcare, digital twins, and the return of the "country doctor" model This episode is for you if: You're curious about biological age vs. chronological age You want to understand what genetic testing can (and can't) tell you You're fascinated by AI's role in the future of personalized medicine You want smarter, not harder ways to build resilience and optimize longevity You can also find this episode on… Youtube: https://youtu.be/QQ-kIH3XbF0 Learn more about Dr. Helen Messier: Fountain Life: https://www.fountainlife.com/ Instagram: https://www.instagram.com/fountainlife/ Website: https://www.ifm.org/educator/helen-messier LinkedIn: https://www.linkedin.com/in/helen-messier-phd-md/ Find more from Smarter Not Harder: Website: Smarter Not Harder Podcast Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% off your purchase of the Metabolomics module with code PODCAST10 at https://www.homehope.org/ Get 10% off your Troscriptions purchase with code POD10 at https://www.troscriptions.com/ Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Dr. Alan Gaby joins Jodi Duval to explore over five decades of clinical experience in nutritional medicine. From vitamin C and magnesium to hidden food allergies and the Myers' Cocktail, this conversation unpacks what actually works — and why much of it is still ignored by conventional medicine. Join us as we delve into: • Why magnesium may be the most overlooked nutrient deficiency • Folic acid vs. methylfolate — what the research really says • The truth about vitamin C, IV therapy, and immune resilience • Hidden food allergies as root causes of chronic disease • Niacinamide for osteoarthritis, skin cancer prevention, and glaucoma • How to break sugar addiction and stabilize blood sugar naturally This episode is for you if: • You want evidence-based nutritional medicine — not hype • You're curious about elimination diets and hidden food sensitivities • You've heard conflicting advice about methylated vitamins • You want simple, practical strategies to improve long-term health You can also find this episode on… YouTube: https://youtu.be/sTwlRtbCK-w Find more from Dr. Alan Gaby:Website: https://doctorgaby.com Nutritional Medicine (Textbook): https://doctorgaby.com/nutritional-medicine/LinkedIn: https://www.linkedin.com/in/alan-gaby-44310721/ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% off your purchase of the Clinical Metabolomics module with code PODCAST10 at https://www.homehope.org/ Get 10% off your Troscriptions purchase with code POD10 at https://www.troscriptions.com/ Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Dr. Linda Kiley joins Dr. Scott Sherr for a groundbreaking conversation on functional urogynecology — exploring the real causes of pelvic and bladder pain that most conventional models miss. Dr. Kiley shares how she uses muscle exams, peptide protocols, and root-cause diagnostics to treat conditions like interstitial cystitis, chronic UTIs, pelvic floor dysfunction, and endometriosis — often without surgery or long-term antibiotics. If you or someone you love has been told "there's nothing wrong" but still struggles with pelvic discomfort, bladder issues, or sexual pain, this episode is a must-listen. Join us as we explore: • The pelvic floor as a dynamic system — not just "tight or weak" • Biofilms, interstitial cystitis, and smart testing for chronic infections • How gut health and systemic inflammation drive pelvic pain • Natural, non-invasive approaches to bladder and pelvic restoration This episode is for you if: • You experience chronic UTIs, bladder discomfort, or pelvic pain • You've been dismissed or misdiagnosed by conventional providers • You're a clinician seeking better diagnostics for pelvic dysfunction • You want to understand how muscle tone, breathing, and biofilms intersect You can also find this episode on… YouTube: https://youtu.be/JLZ5iIBFkls?si=yaoHg-qrxF2XCx1n Find more from Dr. Linda Kiley: Website: https://drlindakiley.com/ Instagram: https://www.instagram.com/drkileyurogyn/ YouTube: https://www.youtube.com/@theholisticurogynecologist3891 LinkedIn: https://www.linkedin.com/in/linda-kiley-5999462b/ More from Smarter Not Harder: Website: Smarter Not Harder podcast Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% off your purchase of the Clinical Metabolomics module with code PODCAST10 at https://www.homehope.org/ Get 10% off your Troscriptions purchase with code POD10 at https://www.troscriptions.com/ Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Grace Hawkins joins Jodi Duval to share her inspiring journey from medical misdiagnosis to becoming a personalized health mentor. With a background in naturopathy and clinical diagnostics, Grace blends DNA, blood chemistry, and HTMA testing to help her clients uncover the root causes of dysfunction and reclaim agency in their health journey. From endometriosis and burnout to lab interpretation and emotional patterns, this episode is a roadmap for how to think critically, test wisely, and personalize healing in a system that often fails to see the whole picture. Join us as we explore: • Grace's approach to personalized testing: DNA, HTMA & blood • Emotional patterns, heavy metals & how HTMA reveals hidden stories • How to empower clients with data and narrative — not just prescriptions • The future of health mentorship and integrative practitioner models This episode is for you if: • You've been told "your labs are normal" — but you still don't feel right • You're curious about DNA or hair mineral testing but don't know where to start • You're a clinician seeking a smarter approach to functional workups • You believe healing means slow medicine — not just instant fixes You can also find this episode on... Youtube: https://youtu.be/F4MFhNAheic Learn more about Grace Hawkins: LinkedIn: https://www.linkedin.com/in/grace-hawkins-a2260b69/ Facebook: Health with Grace | Byron Bay NSW Instagram: Grace Hawkins (BHSc) (@healthwithgrace_) • Instagram profile Website: Home - Health With Grace Find more from Smarter Not Harder: Website: Smarter Not Harder podcast Instagram: Troscriptions (@troscriptions) • Instagram profile HOMeHOPe Virtual Symposium 2026: HOMeHOPe Virtual Symposium 2026 - HOMeHOPe Get 10% off your purchase of the Clinical Metabolomics module with code PODCAST10 at Let's bring Health HOMe - HOMeHOPe. Get 10% off your Troscriptions purchase with code POD10 at Troscriptions® - Buccal Troches for Health Optimization. Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Dr. Amanda Wiggins joins Jodi Duval to explore one of the most promising frontiers in longevity and neuroscience: brain vascular health. From her discovery of CGP (cyclic glycine-proline) to the science behind neurovascular aging, Dr. Wiggins explains why capillaries, inflammation, and even insulin play a much bigger role in dementia than most people realize. From biotech insights to personal stories, this conversation reveals what we can all do — starting now — to protect our brains as we age. Join us as we explore: • What CGP is and how it supports the blood-brain barrier   • How brain vascular health is central to dementia prevention   • Why IGF-1, capillaries, and inflammation matter more than we thought   • How to start optimizing brain health — simply and effectively This episode is for you if: • You want to understand the vascular root of cognitive decline   • You're looking for emerging therapies to support brain health   • You're navigating aging, menopause, or brain fog   • You believe that prevention is smarter than hard treatment You can also find this episode on… YouTube: https://youtu.be/xx8L00x7PGI Learn more about Dr. Amanda Wiggins:Website: https://cgpmax.com/ LinkedIn: https://www.linkedin.com/in/amandawiggins/ Find more from Smarter Not Harder:   Website: https://troscriptions.com/blogs/podcast Instagram: https://www.instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% Off your purchase of the Clinical Metabolomics module with code PODCAST10 at Let's bring Health HOMe - HOMeHOPe Get 10% Off your Troscriptions purchase with code POD10 at Troscriptions® - Buccal Troches for Health Optimization Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Ryan Carter joins Dr. Scott Sherr for a refreshingly real, honest, and grounded conversation about what's broken in the "biohacking" and health optimization world — and how to fix it. Ryan, a UK-based remote health practitioner, shares his journey from extreme protocols and burnout to balanced clinical systems that support long-term health. From redox before detox to seasonal eating, mold, light, water, and remote testing, this is the practitioner's perspective you rarely hear. Join us as we explore: • The top 5 health mistakes smart people still make   • Redox before detox: why energy must come first   • The dangers of extreme tribes and supplement obsession   • Clinical pearls for mold, light, and remote health testing This episode is for you if: • You're overwhelmed by protocols, labs, and conflicting health advice   • You've tried everything but still feel stuck or exhausted   • You're a clinician building an online or remote practice   • You want smarter, not harder ways to test, treat, and live You can also find this episode on…YouTube: https://youtu.be/PdkzQmQMMdU Find more from Ryan Carter:   Website: https://www.livevitae.com Instagram: https://www.instagram.com/livevitae LinkedIn: https://www.linkedin.com/in/livevitae/ Find more from Smarter Not Harder:   Website: https://troscriptions.com/blogs/podcast?utm_source=youtube&utm_medium=video&utm_campaign=snh_podcast_guest_episode_2025_10&utm_content=podcast_asset Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% Off your purchase of the Clinical Metabolomics module with code PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase with code POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, Dr. Libby Weaver joins Jodi Duval for an illuminating conversation about iron — the most overlooked yet essential nutrient for mood, cognition, metabolism, and long-term health. Together, they break down myths, lab test pitfalls, supplement confusion, and why so many women and children remain iron-deficient despite "normal" results. From hepcidin and hormone shifts to sport, anxiety, and pregnancy, this is the deep dive into iron you didn't know you needed. Join us as we explore: • What hepcidin is and why it's the key to iron absorption   • Why teenage girls and high-performing women are so often iron-deficient   • Iron infusions: when they're needed — and when they're not   • Testing errors, supplement types, and food-based solutions This episode is for you if: • You've ever been told your iron is "normal" but still feel exhausted   • You've had recurring iron infusions or failed supplements   • You're a practitioner wanting clarity on dosing, testing, and absorption   • You want to support kids, teens, and athletes with better iron strategies You can also find this episode on…Youtube: https://youtu.be/chuWc53iw2g Find more from Dr. Libby Weaver:   Website: https://www.drlibby.com Instagram: https://www.instagram.com/DrLibby/ Facebook: https://www.facebook.com/DrLibbyLive YouTube: https://www.youtube.com/@drlibby6300 LinkedIn: https://www.linkedin.com/in/dr-libby-phd-3a497531/ Find more from Smarter Not Harder:   Website: https://troscriptions.com/blogs/podcast?utm_source=youtube&utm_medium=video&utm_campaign=snh_podcast_guest_episode_2025_10&utm_content=podcast_asset  Instagram: https://www.instagram.com/troscriptions HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% Off your purchase of the Clinical Metabolomics module with code PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase with code POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.