ReInvent Healthcare podcast

Appetite Signals Decoded: Why Clients Stay Hungry Despite Eating Well

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Your clients eat full meals, yet cravings persist. Nighttime snacking, blood sugar swings, and constant hunger aren’t willpower. They’re signals. Appetite is controlled by a complex network of hormones, the nervous system, gut, microbiome, muscle, and nutrient status.

In this episode, Dr. Ritamarie Loscalzo explains why focusing on a single hormone like GLP-1 isn’t enough. She shows how to identify the patterns driving overeating, cravings, and metabolic dysregulation, so you can address the root cause rather than just the symptoms.

What’s Inside This Episode

  • Why appetite is a communication system, not just a numbers problem
  • How ghrelin, leptin, insulin, GLP-1, PYY, and CCK work together to signal satiety
  • The hidden impact of stress, sleep, and reward pathways on cravings
  • How muscle, metabolism, and the microbiome shape hunger signals
  • Why post-meal hunger often reflects systemic dysfunction
  • A pattern-based approach to uncover root causes of persistent appetite issues

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