Lisata Therapeutics expands drug discovery with GATC AI collaboration

Pinnacle Silver & Gold Corp (TSX-V:PINN, OTCQB:NRGOF) president and CEO Robert Archer talked with Proactive's Stephen Gunnion about the company’s latest acquisition, the El Potrero mine in Mexico. Archer explained that the company is focused on fast-tracking the project towards production within two to three years, aiming to build the business through cash flow rather than relying on external markets. El Potrero was previously in production in the late 1980s, with existing underground workings and a 100-ton-per-day processing plant. Archer highlighted that much of the infrastructure remains in place, which should help streamline redevelopment efforts at a relatively low cost. The company plans to rehabilitate the underground workings, conduct systematic sampling, and commence drilling to establish a resource base sufficient to restart production. On the financial side, Pinnacle Silver recently raised $800,000 in a private placement, with plans to secure up to $2–$3 million over the next few years to fully fund the restart. Archer also shared insights from the PDAC conference, noting positive sentiment around metals despite broader economic uncertainties. The company expects a strong news flow this year as exploration and development efforts accelerate. For more updates, visit Proactive’s YouTube channel. Don’t forget to like, subscribe, and turn on notifications for the latest news. #Mining #Gold #Silver #PinnacleSilver #MexicoMining #ResourceStocks #JuniorMining #GoldInvestment #MiningExploration #PreciousMetals

Lisata Therapeutics Inc (NASDAQ:LSTA) CEO David Mazzo talked with Proactive about the company’s strategic collaboration with GATC Health, a leader in artificial intelligence-driven drug discovery. Mazzo explained that GATC’s technology, which is recognized by Lloyd’s of London for clinical trial risk assessment, will be used to analyze Lisata’s lead candidate, certepetide, and identify potential new drug combinations. Mazzo highlighted that this collaboration will optimize Lisata’s ongoing cancer research, including trials in pancreatic ductal adenocarcinoma, cholangiocarcinoma, and other cancers. He noted that GATC’s AI technology can perform billions of simulations rapidly, potentially reducing the cost and risk of drug development. Discussing Lisata’s 2025 outlook, Mazzo described it as a "data-rich year," with upcoming results from the ASCEND trial and other studies. He emphasized the potential for certepetide in combination with immunotherapy and the company’s ongoing discussions with regulatory agencies and potential partners. To watch more interviews like this, visit Proactive’s YouTube channel. Don't forget to like this video, subscribe, and enable notifications for future updates. #LisataTherapeutics #Biotech #CancerResearch #AIinHealthcare #DrugDevelopment #ClinicalTrials #GATCHealth #Pharma #Oncology #Investing

Europa Oil & Gas (Holdings) Plc (AIM:EOG) CEO Will Holland talked with Proactive's Stephen Gunnion about the company's submission of a planning application for the Cloughton appraisal well in Yorkshire. The application seeks approval to drill and test a gas field originally discovered in 1986. Holland explained that advancements in technology and improved gas prices now make it viable to extract gas at commercial rates. The appraisal well will determine the feasibility of full-field development. He also discussed the launch of a dedicated community engagement website, designed to provide local stakeholders with transparent information, including independent environmental and regulatory reports. Holland emphasised that the project follows strict UK regulations and aims to minimise environmental impact. Addressing concerns, he clarified that fracking is not involved, citing confirmation from Energy Minister Michael Shanks. He also noted that increased heavy goods vehicle (HGV) traffic would be minimal, at around 1% during operations. Holland stressed the project's potential benefits, including job creation and reducing the UK's reliance on imported liquefied natural gas (LNG). “If you're concerned about the environment, you should be supporting domestic gas production. And that's exactly what this is,” he stated. For more interviews with industry leaders, visit Proactive’s YouTube channel. Don't forget to like this video, subscribe, and turn on notifications for updates! #EuropaOilAndGas #EnergySecurity #NaturalGas #UKGas #CloughtonWell #EnergyTransition #Investing #OilAndGas #SustainableEnergy #LNG

Race Oncology Ltd CEO and managing director Daniel Tillett talked with Proactive about the company’s development of a reformulated cancer drug aimed at improving chemotherapy treatment. Tillett discussed the challenges of chemotherapy, including severe side effects, and how Race Oncology is working to minimise these risks while enhancing treatment effectiveness. He explained that the company has taken an older, previously approved drug and developed a new formulation that improves its delivery while protecting patients from heart-related side effects. This new approach, which involves combining the reformulated drug with anthracyclines, aims to enhance cancer treatment while reducing long-term health risks for patients. Tillett highlighted the significant market potential for the company’s drug, given that anthracyclines remain a cornerstone of cancer treatment. The company is now advancing into clinical trials, with results expected to provide key insights into the drug’s effectiveness in humans. Watch the full interview to learn more about Race Oncology’s latest advancements. Don’t forget to like this video, subscribe to Proactive’s YouTube channel, and turn on notifications for more updates on cutting-edge biotech developments. #RaceOncology #CancerTreatment #Biotech #Chemotherapy #Pharmaceuticals #DrugDevelopment #ClinicalTrials #OncologyResearch #Investing #CancerResearch #Cardioprotection

West Cobar Metals Ltd (ASX:WC1) managing director Matt Szwedzicki talked with Proactive's Jonathan Jackson about the company’s latest metallurgical results from the Bulla Park project. Early-stage testing has delivered high-grade copper, silver, and antimony concentrates with strong recoveries. Szwedzicki described the initial float test results as amazing. A key challenge at Bulla Park has been the presence of tetrahedrite, a less common mineral in Australia. However, recent testing has demonstrated successful separation and recovery processes. The company has now achieved 88% extraction of antimony, a commodity that has surged in value due to reduced exports from China. Szwedzicki also discussed West Cobar’s broader strategy, including plans to optimise metallurgical processes, assess a mineral resource estimate, and advance drilling at Bulla Park. Beyond this, the company is progressing its Salazar project in Western Australia, which holds rare earths, scandium, and alumina resources. The recent acquisition of the Mystique Gold Project further strengthens West Cobar’s portfolio, adding a promising gold exploration target. Stay tuned for more updates from West Cobar Metals. If you enjoyed this interview, give the video a like, subscribe to Proactive’s YouTube channel, and turn on notifications for the latest mining insights. #WestCobarMetals #Copper #Antimony #Mining #ASX #BullaPark #RareEarths #GoldExploration #Metals #Investing #Resources

GTI Energy Ltd CEO Bruce Lane talked with Proactive about the latest developments at the Lo Herma in-situ recovery (ISR) Uranium Project in Wyoming. Lane highlighted key findings from recent scoping study fieldwork, including updated resource estimates of 8.57 million pounds, with 30% in the indicated category. He noted that metallurgical testing produced positive leach test results, aligning with nearby uranium projects. GTI Energy also completed permeability testing and water monitoring wells, confirming sufficient water levels and favourable mineralization conditions for ISR mining. Lane emphasized that these results reinforce the feasibility of uranium extraction at Lo Herma, placing it in line with existing ISR operations in Wyoming. He outlined the company’s next steps, including finalizing the scoping study and preparing for further permitting and potential project expansion. Lane also discussed the strong uranium market fundamentals, citing U.S. utilities' annual demand of 50 million pounds versus current domestic production of only 1–2 million pounds. With growing interest in US-based uranium supply and favourable regulatory conditions, GTI Energy continues to advance its Wyoming uranium assets. For more exclusive interviews and updates, visit Proactive’s YouTube channel. Don’t forget to like this video, subscribe, and turn on notifications for the latest insights. #GTIEnergy #UraniumMining #LoHermaProject #ISRMining #WyomingUranium #UraniumStocks #EnergySector #MiningNews #BruceLane #NuclearEnergy

Astral Resources NL (ASX:AAR) managing director Marc Ducler talked with Proactive about the latest gold recovery results from the Mandilla Gold Project in Western Australia. He shared insights into recent metallurgical test work at the Theia prospect, where 87% gravity recovery and 98% overall recovery were achieved within 24 hours. Ducler highlighted that these strong results support the upcoming mineral resource estimate and pre-feasibility study. The company is optimising the resource estimate using a A$3,500 gold price and current mining and processing cost assumptions. The updated resource model is expected within two weeks, with the pre-feasibility study targeted for release in the June quarter. Ducler also provided an update on Astral’s takeover of Maximus Resources, which has reached a 72% acceptance level. The acquisition adds 330,000oz to Astral’s resource base and provides future infrastructure opportunities. Additionally, the company has active drilling programs, including diamond drilling at Camp Man, an air core program at Feysville, and a 46-hole RC drilling campaign set to begin shortly. For more insights from Astral Resources, visit Proactive’s YouTube channel. Don’t forget to like the video, subscribe, and enable notifications for future updates.

TNR Gold Corp (TSX-V:TNR, OTC:TRRXF) executive chairman Kirill Klip talked with Proactive's Stephen Gunnion about the company’s latest developments, including a key milestone in its transition to a cash-flow-generating royalty business. Klip highlighted that TNR Gold holds royalties on significant projects, including the Los Azules Copper project and the Mariana Lithium project in Argentina. With Los Azules now applying for Argentina's incentive regime for large investments, he explained that the project could see substantial tax reductions, making it easier to attract the $2.7 billion investment required for construction. Discussing Argentina’s economic reforms under President Javier Milei, Klip noted that the country's policies are encouraging large-scale investment in the mining sector. He also pointed to the environmental permit secured for Los Azules, bringing it closer to a construction decision, with a feasibility study expected in the first half of the year. Klip also shared insights from Fundamental Research Corporation’s latest analysis, which increased its price target for TNR Gold from $0.24 to $0.28, underscoring the company's transition from a project generator to a cash-flow-generating royalty company. Watch the full interview for more insights into TNR Gold’s latest developments. For more interviews like this, subscribe to Proactive’s YouTube channel, give this video a like, and turn on notifications for future updates! #TNRGold #MiningInvesting #LosAzules #CopperMining #LithiumInvesting #MiningStocks #ArgentinaMining #RoyaltyCompany #StockMarket #JavierMilei

Bitwise Asset Management European head Bradley Duke talked with Proactive about Bitcoin’s recent price movements and the company’s latest product launch. Duke discussed the volatility of Bitcoin, noting both its tailwinds—such as increased demand from corporate investors and national reserves—and the headwinds, including geopolitical uncertainties. He pointed out that institutional investors are turning instead to alternative safe-haven assets like gold. The conversation then shifted to Bitwise’s latest product, Bitwise Diaman Bitcoin & Gold ETP (BTCG), which launched today on Euronext in Paris and Amsterdam. Duke explained that the product is a collaboration with Diaman Partners, part of asset manager Azimut. The ETP dynamically allocates between Bitcoin and gold based on an index that considers drawdowns and recovery rates. "We’ve looked at the performance of this index versus the S&P 500, Nasdaq 100, and gold alone, and it has outperformed considerably," said Duke. He emphasised that while past performance is no guarantee of future results, the product arrives at a time when institutions are actively seeking alternative safe-haven assets. For more insights and interviews, visit Proactive’s YouTube channel. Don’t forget to like, subscribe, and enable notifications for updates. #Bitcoin #Gold #BTCG #Bitwise #CryptoInvesting #DigitalAssets #SafeHaven #ETP #Investment #Markets

Wedgemount Resources CEO Mark Vanry joined Steve Darling from Proactive to provide an update to Proactive on the company's field activities at its recently acquired Huggy Assets. After weather-related delays, Wedgemount has full operations going, including pumping, surface facility optimization, maintenance, chemical treatments, and well workovers. The company's primary focus remains on the Echo and Novice operational areas, where five additional wells have been brought back online. These wells had been inactive for a significant period before Wedgemount's acquisition. Historical initial production (IP) rates for these wells ranged from 15 to 65 barrels of oil equivalent per day (boepd). Vanry noted that previous successful chemical stimulations on Wedgemount’s Willowbend leases resulted in improved well performance. The company expects similar or better results from workovers and chemical treatments at Huggy, potentially exceeding the original IP rates. Looking ahead, Wedgemount has over 100 additional wells that have yet to undergo chemical stimulation, presenting significant production upside over the next two years. #proactiveinvestors #westmountreosurcescorp #cse #wdgy #otcqb #wdgrf #OilProduction #TexasEnergy #EnergyInvesting #OilandGas #MarkVanry #ProactiveInvestors #EnergyStocks #Investing #OilExploration