Health Freedom Defense | Leslie Manookian - E417

Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Adam Moskowitz is the King of Cheese—but his path to the throne was anything but straight. In this delicious episode of Infinite Loops, Adam shares his wild journey from a failed rap career and a battle with addiction to becoming one of the most influential figures in cheese and the host of A Cheese Course. Whether you are a foodie, a creator battling gatekeepers, or just someone who loves a good comeback story, this episode will remind you to bet on yourself—and maybe eat some better cheese while you're at it. I hope you enjoy the conversation as much as I did. For the full transcript, episode takeaways, and bucketloads of other goodies designed to make you go, "Hmm, that's interesting!", check out our Substack. Show Notes: The "Cheese Quake" origin story and the failed rap career Why "Creamy" is a texture, not a flavor The Artisan Cheese Illuminati Creating a documentary when gatekeepers said "No" The "Olive Garden" insult that fueled a fire Is the "Banana on the Wall" actually art? Cognitive diversity and why echo chambers kill creativity The "Time Horizon is Infinite" philosophy Leaders Lead & Lead with Love Books & Ideas Mentioned: My Dinner with Andre (Movie) Candide by Voltaire (Dr. Pangloss) Kubla Khan by Samuel Taylor Coleridge Claude Shannon (Information Theory)

Low Carb MD: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Leslie Manookian, MBA, M.L.C. Hom, is the president and founder of the Health Freedom Defense Fund and a former Wall Street executive. Her finance career took her from New York to London with Goldman Sachs before she became Director at Alliance Capital, overseeing European Growth Portfolio Management and Research. Leslie is also an award-winning documentary filmmaker. In 2011, she wrote and produced The Greater Good, a critically acclaimed film exploring the vaccine debate and sparking wider conversation about medical choice and personal liberty. Motivated by years of watching Americans' constitutionally protected rights erode, Leslie founded HFDF to defend medical and health freedoms nationwide. She believes bodily autonomy is a fundamental human right and works tirelessly to advance and protect it through public awareness and legal action.   In this episode, Dr. Tro and Leslie talk about… (00:00) Intro (02:05) Why she left Wall Street to advocate for medical freedom (10:40) Deaths in clinical trials for pharmaceuticals (14:45) Industry trade groups that are a huge part of the chronic disease epidemic (19:40) How more of the public can be woken up to the realities of the corruption taking place in the medical and pharmaceutical industries (32:21) The work of the Weston A. Price Foundation (39:55) The responsibilities of doctors and patients (45:51) Leslie's recent work with the Health Freedom Defense Fund fighting for peoples' rights (01:01:04) The Greater Good   For more information, please see the links below. Thank you for listening!   Links:   Please consider supporting us on Patreon: https://www.lowcarbmd.com/   Leslie Manookian: Health Freedom Defense Fund: https://healthfreedomdefense.org/ Nutrition and Physical Degeneration (book): https://www.amazon.com/Nutrition-Physical-Degeneration-Weston-Price/dp/0916764206 The Weston A. Price Foundation: https://www.westonaprice.org/#gsc.tab=0 Green Med Info: https://greenmedinfo.com/   Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author   Dr. Tro Kalayjian:  Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/   Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.    Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/ 

Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Antonio Bianco is a world-renowned physician-scientist and expert in thyroid physiology and metabolism. In this episode, Antonio explores the complex biology of thyroid hormone production, conversion, and regulation—highlighting how deiodinase enzymes modulate hormone activity at the tissue level and why that matters for interpreting lab results. He discusses the shortcomings of relying solely on TSH as a marker of thyroid function, the ongoing debate around combination therapy with T3 and T4 versus standard T4 treatment, and how genetics, tissue sensitivity, and individual variability influence thyroid hormone metabolism. The conversation also examines how hypothyroidism affects energy, mood, cognition, and longevity; why some patients remain symptomatic despite "normal" labs; and how future research could reshape treatment paradigms. We discuss: How the thyroid produces, stores, and activates hormones like T4 and T3 to finely regulate thyroid activity [2:45]; How fasting alters thyroid hormones to conserve energy [12:45]; Action of the deiodinases: how D1, D2, and D3 enzymes control the activation and inactivation of thyroid hormones [19:15]; The normal function of thyroid hormone and the roles of the hypothalamus, pituitary gland, and deiodinases in maintaining hormonal balance [23:30]; Why understanding thyroid physiology is essential for proper diagnosis and treatment of hypothyroidism [33:45]; Testing for thyroid hormones: understanding free vs. total levels, the limitations of current T3 assays, best practices, and more [36:00]; Genetic and sex-based variability in thyroid hormone regulation and their limited clinical significance [43:45]; Hyperthyroidism: causes, symptoms, diagnosis, and treatment options [46:00]; Hypothyroidism: diagnosis and autoimmune causes of hypothyroidism [56:30]; More on hypothyroidism: diagnostic biomarkers, antibody patterns, and non-autoimmune presentations [1:05:00]; Thyroid hormone replacement therapy [1:15:15]; More on thyroid replacement strategies: exploring the evidence gaps, mortality signals, effects on lipids, and more [1:28:00]; Hypothyroidism basics: causes, antibody implications (including pregnancy), and how to make the diagnosis before choosing therapy [1:35:15]; Thyroid medication: compounded controlled-release T3, brand name versus generic, and what Antonio prescribes to newly diagnosed hypothyroid patients [1:42:45]; Redefining treatment success: why normalizing TSH isn't always enough for patients with hypothyroidism [1:54:45]; Case studies: analysis of two unusual cases of thyroid disease [1:57:00]; Dangers of supplementing with high levels of iodine, and female-specific risk of thyroid disease [2:05:45]; Case study of a patient who presents with elevated TSH but no symptoms [2:09:30]; How future research could reshape treatment, and Antonio's new book called "Rethinking Hypothyroidism" [2:13:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Emmett Shear, founder of Twitch and former OpenAI interim CEO, challenges the fundamental assumptions driving AGI development. In this conversation with Erik Torenberg and Séb Krier, Shear argues that the entire "control and steering" paradigm for AI alignment is fatally flawed. Instead, he proposes "organic alignment" - teaching AI systems to genuinely care about humans the way we naturally do. The discussion explores why treating AGI as a tool rather than a potential being could be catastrophic, how current chatbots act as "narcissistic mirrors," and why the only sustainable path forward is creating AI that can say no to harmful requests. Shear shares his technical approach through multi-agent simulations at his new company Softmax, and offers a surprisingly hopeful vision of humans and AI as collaborative teammates - if we can get the alignment right. Resources:Follow Emmett on X: https://x.com/eshearFollow Séb on X: https://x.com/sebkrierFollow Erik on X: https://x.com/eriktorenberg Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.   Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Mind Pump Fit Tip: 10 amazing and weird ways probiotics benefit you. (2:14) Silicon Valley espionage. (18:45) Uncomfortable experiences training clients. (28:37) Iron sharpens iron. (33:51) Prioritizing your relationship above your kids, and the importance of establishing family values/foundations. (40:28) Fostering good bacteria growth with the Green Juice from Organifi. (50:41) Must-haves when building your house. (52:33) #ListenerLive question #1 – No matter what I do, I cannot gain muscle or weight. Please help. (1:00:57) #ListenerLive question #2 – I'm looking for advice on what program to do after completing Anabolic Advanced? (1:10:28) #ListenerLive question #3 – My current life routine only allows me to go to the gym 1 day per week, and maybe some weeks I will be able to squeeze in a second until March. Is there a program that you would recommend I follow during this time span? (1:18:48) #ListenerLive question #4 – I'm having a hard time gauging my results from Muscle Mommy. I was wondering if that is just how the program is written, as most women fear "getting bulky," or if my additional activity is hindering my progress? (1:33:00) Related Links/Products Mentioned Ask a question to Mind Pump, live! Email: [email protected] Visit Seed for an exclusive offer for Mind Pump listeners! **Promo code 25MINDPUMP at checkout for 25% off your first month's supply of Seed's DS-01® Daily Synbiotic** Visit Organifi for the exclusive offer for Mind Pump listeners! **Promo code MINDPUMP at checkout for 20% off** November Black Friday Deals (Nov. 1-15th): Sitewide 60% off. That includes every single MAPS program, bundle, MOD, and guide. Enter the raffle now to win HUGE prizes: Bundles give you 10 entries, MAPS program gives you 3 entries, MODs or guides give you 1 entry. For programs go HERE. Enter the code BLACKFRIDAY at checkout.  Mind Pump Store Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota Probiotics for Eczema: A Science-Backed Guide for Skin Health How Probiotics Can Help You Lose Weight and Belly Fat How Silicon Valley Became a Den of Spies - POLITICO Sal Di Stefano's Journey in Faith & Fitness – Mind Pump TV Mind Pump #1665: How Gyms Survived Shutdowns With Jason Khalipa Mind Pump #2290: Becoming a Better Man With Jason Khalipa Mind Pump #2225: How to be a Great Parent & Raise Successful Children With Adam Lane Smith Get a free Sample Pack of LMNT's most popular drink mix flavors with any purchase! As always, LMNT offers no-questions-asked refunds on all orders. The 8-count LMNT Sample Pack doubles down on our most popular flavors: Citrus Salt, Raspberry Salt, Watermelon Salt, and Orange Salt (2 stick packs of each flavor): Visit DrinkLMNT.com/MindPump Mind Pump #2684: Do ONLY These 8 Lifts to Achieve an Amazing Body Muscle Mommy Movement Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Peter Attia, M.D. (@peterattiamd) Instagram Jason Khalipa (@jasonkhalipa) Instagram Corinne Schmiedhauser (@mindpumpcorinne) Instagram  

Founders ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Todd Graves is one of my favorite living founders. He owns over 90% of Raising Canes — a business that is worth at least $20 billion. Todd's maxim is "Do one thing and do it better than anyone else." It is impossible not to be inspired by his terminator levels of determination. I hope you enjoy our conversation as much as I did. Episode show notes: ⁠https://www.davidsenra.com/episode/to... Made possible by Ramp: ⁠⁠https://ramp.com⁠⁠ HubSpot: ⁠⁠https://hubspot.com⁠⁠ Function: ⁠https://functionhealth.com/senra⁠ Chapters (00:00) The Entrepreneurial Mindset: Sleep and Business Obsession (02:13) The Birth of Raising Cane's: Overcoming Skepticism (03:29) Inspiration from In-N-Out Burger (07:17) The Importance of Quality and Focus (14:49) The Journey to Success: Hard Work and Sacrifice (19:21) The Early Days: Building Raising Cane's from Scratch (21:23) Financing the Dream: Unconventional Paths (32:28) The Relentless Pursuit of Success (33:02) Commitment and Oaths: The Camping Trip (34:02) Fanaticism and Relentless Focus (34:53) Learning from Others and Continuous Improvement (35:06) The Never-Satisfied Mindset (36:04) The Importance of Founders in Business (39:55) The Purpose Beyond Profit (51:52) Financing the Dream: Credit Cards and SBA Loans (55:47) Building the First Restaurant (57:56) Expanding the Vision (58:59) Positive Motivational Management (01:00:51) Creating a Coaching Culture (01:01:42) Intrinsic Motivation vs. Titles (01:02:41) The Importance of Being Present (01:06:35) Respect, Recognition, and Rewards (01:09:12) The Power of Encouragement (01:18:10) The Myth of Delegation (01:22:57) Focus on What You Do Best (01:30:07) Dining at Jiro in Tokyo (01:30:59) The Franchise Model Debate (01:32:50) Challenges of Franchising (01:35:21) Building a Business Authentic to You (01:37:07) Financing and Expansion Strategies (01:49:13) Surviving Hurricane Katrina (01:55:48) Lessons from Estée Lauder (01:58:06) Final Thoughts and Reflections

Fitt Insider: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Today, I'm joined by Jared Pobre, founder & CEO of Caldera + Lab.   Launched in 2019, Caldera + Lab is revamping men's medicine cabinets with proprietary premium skincare formulas specifically engineered for guys.   In this episode, we discuss building a biotech-driven men's personal care brand.   We also cover:   Targeting the longevity-minded male consumer Prioritizing proprietary R&D over repurposed formulas Developing distribution strategies and hospitality partnerships   Subscribe to the podcast → insider.fitt.co/podcastSubscribe to our newsletter → insider.fitt.co/subscribeFollow us on LinkedIn → linkedin.com/company/fittinsider Caldera + Lab's Website: www.calderalab.com  Amazon: https://www.amazon.com/stores/CalderaLab/page/2A608586-7E58-411C-8057-FFD688968227   -   The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart workout solutions for fitness and health facilities.   Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/    Chapters: (00:00) Introduction (01:08) Jared's background and Caldera + Lab overview (01:33) The evolution of men's skincare since 2016 (03:02) Formulation differences: women's vs. men's skincare (04:32) Custom formulations vs. menu-based co-manufacturing (06:24) Pioneering proprietary ingredients for men (08:00) Building the brand with bootstrapped resources (10:30) Clinical studies and efficacy testing (13:00) Customer acquisition and finding product-market fit (15:30) DTC and Amazon as core distribution channels (17:45) Storytelling and messaging strategy (21:53) Balancing scientific credibility with consumer messaging (23:12) Targeting the longevity-minded male consumer (25:11) Retail expansion strategy and Series A funding (26:15) Country clubs, luxury hotels, and hospitality partnerships (27:26) Product roadmap (28:49) Conclusion  

Recode Decode: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- We keep hearing over and over that generative AI is causing massive problems in education, both in K-12 schools and at the college level. Lots of people are worried about students using ChatGPT to cheat on assignments, and that is a problem. But really, the issues go a lot deeper, to the very philosophy of education itself. We sat down and talked to a lot of teachers — you’ll hear many of their voices throughout this episode — and we kept hearing one cri du coeur again and again: What are we even doing here? What’s the point? Links:  Majority of high school students use gen AI for schoolwork | College Board Quarter of teens have used ChatGPT for schoolwork | Pew Research Your brain on ChatGPT | MIT Media Lab My students think it’s fine to cheat with AI. Maybe they’re on to something. | Vox How children understand & learn from conversational AI | McGill University ‘File not Found’ | The Verge Subscribe to The Verge to access the ad-free version of Decoder! Credits: Decoder is a production of The Verge and part of the Vox Media Podcast Network. Our producers are Kate Cox and Nick Statt. Our editor is Ursa Wright.  The Decoder music is by Breakmaster Cylinder. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Alain de Botton is a philosopher, author, and founder of The School of Life. How can we truly understand ourselves? Most of us either ignore our emotions or overthink them, turning simple feelings into complex puzzles. So how do we navigate the minefield of emotion to grow and become better? Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a Free Sample Pack of LMNT’s most popular flavours with your first purchase at https://drinklmnt.com/modernwisdom Get 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdom Get Free Travel Packs, Free Liquid Vitamin D, and more from AG1 at https://ag1.info/modernwisdom Get $100 off the best bloodwork analysis in America at https://functionhealth.com/modernwisdom Extra Stuff: Main website: https://www.theschooloflife.com/ Newsletter sign up: https://www.theschooloflife.com/signup/ Shop: https://shop.theschooloflife.com/ Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Get the free investing playbook to invest like Warren Buffet: https://clickhubspot.com/rme Episode 760: Shaan Puri ( ⁠https://x.com/ShaanVP⁠ ) talks to Cathie Wood ( https://x.com/CathieDWood )  about her fund’s performance, her biggest bets on AI, and the most misunderstood stock on earth.  — Show Notes: (0:00) McDonald’s to Managing Billions (8:54) A day in the life of Cathie Wood (17:29) ARK’s Performance Review (30:00) Cathie’s #1 stock pick — Links: • ARK - https://www.ark-funds.com/  • The MFM Newsletter Challenge - https://www.beehiiv.com/application/mfm — Check Out Shaan's Stuff: • Shaan's weekly email - https://www.shaanpuri.com  • Visit https://www.somewhere.com/mfm to hire worldwide talent like Shaan and get $500 off for being an MFM listener. Hire developers, assistants, marketing pros, sales teams and more for 80% less than US equivalents. • Mercury - Need a bank for your company? Go check out Mercury (mercury.com). Shaan uses it for all of his companies! Mercury is a financial technology company, not an FDIC-insured bank. Banking services provided by Choice Financial Group, Column, N.A., and Evolve Bank & Trust, Members FDIC — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam’s List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by HubSpot Media // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano