Episode 468: Sulforaphane

Have you heard of sulforaphane? Want to know how to harness the benefits of this powerful compound? Tune in to learn all about sulforaphane—a powerhouse phytonutrient that activates detox and antioxidant pathways to protect your cells.  In this episode, we will unpack how this potent compound supports the body’s natural defense systems, working through the NRF2 pathway to reduce oxidative stress, enhance cellular detoxification, and promote resilience against modern day toxin exposure. We also discuss how food preparation impacts sulforaphane yield, why gut health matters for its conversion, and how to maximize levels through broccoli sprouts, seed extracts, and targeted supplementation.  We also unveil the exciting reformulation of Cellular Antiox, featuring clinically validated broccoli seed extract for enhanced cellular protection alongside glutathione support! Also in this episode:  Shop NEW Cellular Antiox with code CELLULAR15 Naturally Nourished Academy - Now Enrolling with Early Bird Pricing!  What is sulforaphane? Who can benefit from sulforaphane? Sulforaphane in the research Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer - PubMed Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China - PMC Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects - PubMed Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring - ScienceDirect Broccoli or Sulforaphane: Is It the Source or Dose That Matters? - PMC Sulforaphane treatment of autism spectrum disorder (ASD) | PNAS Prep and cooking to maximize sulforaphane Why the gut microbiome matters Probiotic Challenge Protocol How to get sulforaphane in the diet Considerations for BroccoDetox New Cellular Antiox Formulation Setria® Glutathione (250 mg): Clinically studied, reduced form, ready to use N-Acetylcysteine (1,000 mg): A powerful precursor, provides cysteine to fuel internal glutathione production Broccoli Seed Extract 40mg (2mg glucoraphanin): Activates Nrf2 pathway, upregulates endogenous antioxidant production, including glutathione Vitamin B6 (5 mg): Essential cofactor for amino acid metabolism and methylation, supports efficient detox and glutathione recycling New bovine gelatin capsule with silica as an added feature!   Sponsors for this episode:  This episode is sponsored by FOND Bone Broth, your sous chef in a jar. FOND’s bone broths and tallows are produced in small batches with premium ingredients from verified regenerative ranches. Their ingredients are synergistically paired for maximum absorption, nutritional benefit, and flavor. Use code NATURALLY to save at fondbonebroth.com 

Are you low in glutathione? Feeling sluggish, inflamed, or more sensitive to toxins than you used to be? Maybe you’re catching every bug that goes around or noticing your recovery just isn’t what it used to be. Today on the Naturally Nourished Podcast, we’re talking about the body’s master antioxidant, glutathione, and why it’s essential for immune resilience, detoxification, energy, and longevity. We’ll unpack what glutathione is, why modern life so easily depletes it, and how low levels have been linked to everything from fatigue and joint pain to accelerated aging and chronic disease. Plus, we’ll share simple strategies to help you raise your levels naturally and introduce our newly reformulated Cellular Antiox, now featuring NAC, Setria® glutathione, and broccoli seed extract for enhanced cellular protection and glutathione production. Use the code CELLULAR15 to save 15% off our exciting reformulation of Cellular Antiox! Also in this episode:  What is glutathione and what does it do? Episode 325 All About Glutathione Trends of deficiency Micronutrient Panel How the body produces glutathione Cysteine Whey Protect Glycine Pure Collagen Relax and Regulate Glutamate GI Lining Support Do we store glutathione and does it need to be replenished? How to increase glutathione  Sulfur rich veggies Modulation of plasma antioxidant levels, glutathione S‐transferase activity and DNA damage in smokers following a single portion of broccoli: a pilot study Bone broth FOND Bone Broth use code ALIMILLERRD When to supplement with glutathione Will supplementation make my body stop producing it on its own? NEW Cellular Antiox reformulation A 2015 randomized, double-blind, placebo-controlled study published in the European Journal of Nutrition showed that 250–1000 mg of Setria daily for 6 months significantly increased glutathione levels in whole blood, red blood cells, and lymphocytes. Per 2 Capsules: Setria® Glutathione (250 mg): Clinically studied, reduced form, ready to use N-Acetylcysteine (1,000 mg): A powerful precursor, provides cysteine to fuel internal glutathione production Broccoli Seed Extract 40mg (2mg glucoraphanin): Activates Nrf2 pathway, upregulates endogenous antioxidant production, including glutathione Vitamin B6 (5 mg): Essential cofactor for amino acid metabolism and methylation, supports efficient detox and glutathione recyclingNew bovine gelatin capsule with silica as an added feature! Comparison to liposomal and IV glutathione How to dose 1 capsule twice daily for wellness 2 capsules 2-3 times daily for illness or infection Making Medicinal Honey   This episode is sponsored by: This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co! 

Are you intrigued by the Naturally Nourished Academy but not sure you if make the cut? Are you passionate about food-as-medicine but unclear on how to use it in a career or how to bridge the gap of passion and expertise? In this part two episode, we go deeper into our transformative 12-week Functional Nutrition Mentorship Program, designed to help practitioners and passionate learners elevate their clinical skills, confidence, and impact. In this second installment, we walk through Weeks 7–12 of the curriculum, covering hormones, neurotransmitters, toxins, and how you will learn to address complex neurological and metabolic cases. You’ll hear more participant testimonies on their game-changing experiences and start to see how our program may be the one thing you need to transform your vision into a reality! We also dig into salivary, blood, and urinary metabolites, genetic SNPs, and toxicology panels. In this episode we emphasize the scope and range of participants where you may fit as a wellness coach digging into navigating elimination diets while growing into mastering leaky gut or as a functional medicine practitioner now equipped for nuance of biochemical pathways and targeted nutrient support. No matter what we will empower you with how to expand your career with food-as-medicine and strategic supplementation.  Whether you’re a dietitian, health coach, or simply obsessed with functional nutrition, this episode offers a behind-the-scenes look at how Naturally Nourished Academy helps practitioners build confidence, sharpen critical thinking, and create real transformation for their clients. What is Naturally Nourished Academy? Who is this Program for?  Questions from listeners Understanding scope of practice and liability Curriculum Walkthrough Week 7-12Highlights Understanding Hormones Hormonal shifts with the menstrual cycle and impact Navigating DUTCH and Labrix hormone labs The stress-hormone connection Understanding the HPA-axis Nutrient deficiency and cravings Unpacking stubborn metabolism in complex cases Learning how to get your client into parasympathetic balance Mastering the Detox process with food and supplements SNPs and Epigenetics How to make food-as-medicine a reality? Growing your vision into a successful business Are you ready to take your knowledge of functional nutrition to the next level? Whether you're a health coach, registered dietitian, nutritionist, medical professional, or someone deeply passionate about using food as medicine, our 12-week mentorship program is designed to transform the way you approach health and healing. This immersive mentorship experience provides: Weekly 60-minute + 90-minute live classes led by experienced functional nutrition experts Ali Miller RD LD CDE & Becki Yoo MS RD LD Hands-on learning through weekly case studies, lab reviews, and protocol development with real time feedback Real-world application with practical assignments that you can translate directly into your own clinical practice such as recipe creation, research projects and marketing materials A supportive community of like-minded professionals to grow and learn with Personalized mentorship to help you refine your approach and build confidence Access to a private Slack channel to ask questions, collaborate and pick Ali & Becki’s brains between classes Early enrollment is encouraged and we are now live! We understand this is a significant commitment, both financially and logistically so we’re giving you plenty of time to plan and prepare to make the most of our program. Naturally Nourished Academy launches February 4th and our program runs through May 1st 2026.   Join Here   Sponsors for this episode:  This episode is sponsored by FOND Bone Broth, your sous chef in a jar. FOND’s bone broths and tallows are produced in small batches with premium ingredients from verified regenerative ranches. Their ingredients are synergistically paired for maximum absorption, nutritional benefit, and flavor. Use code ALIMILLERRD to save at https://fondbonebroth.com/ALIMILLERRD.   

Have you always wanted to deepen your understanding of functional medicine? Looking to bring food-as-medicine into your current healthcare practice—or start your own, but not sure where to begin? In this episode, we introduce our transformative 12-week Functional Nutrition Mentorship Program, designed to help practitioners and passionate learners elevate their clinical skills, confidence, and impact. In this first installment, we walk through Weeks 1–6 of the curriculum, covering the foundations of functional medicine and how to start thinking like a clinician. You’ll hear what to expect in the early phases of the program—from mastering the client intake process and connecting symptoms to root causes, to interpreting foundational labs and building personalized anti-inflammatory protocols. We also dig into metabolic, cardiovascular, and digestive health—exploring how to assess thyroid, insulin, and lipid panels, interpret the GI-MAP, and approach gut imbalances like dysbiosis and leaky gut with food-as-medicine and targeted supplementation. Whether you’re a dietitian, health coach, or simply obsessed with functional nutrition, this episode offers a behind-the-scenes look at how Naturally Nourished Academy helps practitioners build confidence, sharpen critical thinking, and create real transformation for their clients. What is Naturally Nourished Academy? Who is this Program for?  Curriculum Walkthrough Week 1-6 Highlights All About Antioxidants   Mastering the client intake process + Start to think like a functional medicine practitioner Anti-Inflammatory Diet  Interpreting foundational labs How to determine your client’s caloric and macro needs Advanced Metabolic health & blood sugar control Heart Health Protocol Advanced Cardiovascular health Understanding Optimal Digestion Microbiome and Gut Infections Elimination Diet & Food Sensitivity Leaky Gut and Bowel Inflammation Are you ready to take your knowledge of functional nutrition to the next level? Whether you're a health coach, registered dietitian, nutritionist, medical professional, or someone deeply passionate about using food as medicine, our 12-week mentorship program is designed to transform the way you approach health and healing. This immersive mentorship experience provides: Weekly 60-minute + 90-minute live classes led by experienced functional nutrition experts Ali Miller RD LD CDE & Becki Yoo MS RD LD Hands-on learning through weekly case studies, lab reviews, and protocol development with real time feedback Real-world application with practical assignments that you can translate directly into your own clinical practice such as recipe creation, research projects and marketing materials A supportive community of like-minded professionals to grow and learn with Personalized mentorship to help you refine your approach and build confidence Access to a private Slack channel to ask questions, collaborate and pick Ali & Becki’s brains between classes Early enrollment is encouraged and we are now live! We understand this is a significant commitment, both financially and logistically so we’re giving you plenty of time to plan and prepare to make the most of our program. Naturally Nourished Academy launches February 4th and our program runs through May 1st 2026.   Join Here Sponsors for this episode:  This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co! 

Do you have dense breasts? Are mammograms always the best option? How can thermography support breast and whole body health? With so much interest in our recent coverage of thermography, this follow-up conversation dug even deeper into the topic with Patricia Bowden Luccardi, CTT, CNMT, LMT. We explore the role of thermography as a tool for breast health monitoring, the risks and considerations tied to mammograms, and special concerns for women with dense or fibrocystic breasts. You will gain a deeper understanding of how different screening methods compare and what proactive steps you can take to better support long-term breast health. Plus learn why wearing a bra might be bad for your breasts, the connection between oral and breast health, and how caffeine can drive excessive estrogen in this jam packed episode!  More about Patricia:  Having studied and taught a variety of natural health modalities and therapies, Patricia Bowden-Luccardi has been a lifetime student of integrative health and wellness.  For over 25 years she has been teaching and providing private consultations on health protocols customized to her clientele’s personal needs.    During the past thirteen years, Patricia has focused her expertise on the natural prevention of breast cancer. She is a professional advocate and practitioner for the promotion of radiation-free thermography.    Her public seminars and lectures are designed to educate women about the serious health risks of environmental toxins, endocrine disruptors, and breast cancer. Her natural protocols including diet, plant-based supplementation and lifestyle changes have revealed extraordinary results that have been later visibly confirmed by thermographic imaging.  Patricia holds licensed certifications in Thermographic Technology, Clinical Massage Therapy, Food as Medicine, and Whole Health Education and lifestyle and wellness coaching. A member of Professional Academy of Clinical Thermology She authored the book Thermography and the Fibrocystic and Dense Breast, a Radiation-Free Guide to Happy Healthy Breasts.   Where to find more about Patricia Luccardi: Thermography and the Fibrocystic and Dense Breast / A Radiation-Free Guide to Happy Healthy Breasts www.patricialuccardi.com Breast Thermography International www.btiscan.com   Also in this episode:  Patricia’s Story What is Thermography Episode 446 Thermography as an Assessment of Wellness  How Sulforaphane can support Breast Health BroccoDetox Thermography vs. Mammogram for Dense Breasts Effectiveness of a noninvasive digital infrared thermal imaging system in the detection of breast cancer Mammography screening does not save lives or breasts | The BMJ Cumulative effects of radiation Naturally Nourished Episode 188 Body Autonomy and Listening to Your Inner Wisdom with Dr. Christiane Northrup Alternatives for dense breasts HER Scan QT Scan  Dr. Jean Simmons Oral health and breast health Naturally Nourished Episode 370 Biological Dentistry with Dr. Joan Sefcik Bras and restrictive clothing Dressed to Kill - Sydney Singer Caffeine and estrogen Lymphatic Drainage and movement Sauna - we love Sunlighten Sauna use code ALIMILLERRD The role of iodine in breast health Naturally Nourished Episode 457 All About Iodine Lugol’s iodine with castor oil for breast massage Hakala labs iodine test Supplements for breast health Plant stem cells nature-provides.com Cellular Antiox AHCC medicinal mushrooms Vitamin D  Vitamin D Blood Spot Test Vitamin D Balanced Blend Dairy and estrogen dominance Success stories Lymph star machine Boobs: The War on Breasts CNB Breast Oil Queen of Thrones Castor Oil Packs   Sponsor for this episode:  This episode is sponsored by Air Doctor.  The indoor air that we breathe can be up to 100 times  MORE polluted than outdoor air, according to the EPA. Indoor air pollutants can cause respiratory symptoms like sneezing, congestion, scratchy throat, and even more serious health problems like lung and heart disease. Introducing AirDoctor, the air purifier that filters out 99.99% of dangerous contaminants so your lungs don’t have to. This includes allergens, pollen, pet dander, dust mites, mold spores and even bacteria and viruses.AirDoctor comes with a 30-day money back guarantee so if you don’t love it, just send it back for a refund, minus shipping!Head to airdoctorpro.com and use promo code ALIMILLERRD and you’ll receive UP TO $300 off air purifiers! Exclusive to podcast customers, you will also receive a free 3 year warranty on any unit, which is an additional $84 value! 

In this episode of the Naturally Nourished Podcast, we focus on three key hormones that can significantly impact metabolism: insulin, leptin, and cortisol. Each of these hormones plays an essential role in regulating energy, hunger, and stress, and when imbalances occur, they may be the underlying cause of a metabolic stall or plateau. The conversation explores how insulin resistance can block fat burn, how leptin resistance can interfere with satiety signals, and how cortisol dysregulation can drive cravings and fat storage. We discuss practical strategies for identifying when these hormones are out of balance, along with food-as-medicine approaches, lifestyle modifications, and targeted supplementation to help restore harmony and support optimal metabolic function. Also in this episode:  Join our Keto Reset Program Naturally Nourished Kids Book Tour Events Insulin Naturally Nourished Episode 459 Why Insulin Matters Improved Skeletal Muscle Insulin Sensitivity Study Rapid Reduction in Insulin Resistance Markers Study Leptin Naturally Nourished Episode 146 Keto as a Hormetic Stressor and Leptin  Naturally Nourished Episode 356 Low Fat Keto for Leptin Resistance What is Leptin and why it matters High vs. Low Leptin Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later? Ideal range for leptin 5-10 Cortisol Metabolic and blood sugar impact The Anti-Anxiety Diet Adrenal Rehab Program Calm and Clear Relax and Regulate Adaptogen Boost How a Keto Reset Supports Insulin, Leptin & Cortisol Regulation   This episode is sponsored by:  According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That’s why you’ve got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off. 

In this episode, we cover your burning questions on our Keto Reset so you can determine if this program is for you. Can you do Keto when pregnant or breastfeeding? Is Keto safe on a GLP-1 medication? Will Keto raise my cholesterol levels? Do I need to take Berberine? We cover all these and more! We also discuss our Keto Reset Program, a food-as-medicine approach designed to support sustainable health and metabolic balance. This episode highlights why our program stands apart by focusing on nourishing, whole foods and personalized guidance that fits your unique needs. Whether you’re new to keto or looking to deepen your understanding, this episode provides clarity and inspiration to take charge of your health with confidence.  Also in this episode:  Keto Reset Program - Starts 9/24! What is a keto reset? Keto miracle babies, the impact of ketosis on fertility Our 3 phase protocol and how carb levels vary based on seasons The Perimenopause plateau: is it real? How can I get off it? Can Red Meat increase my risk for heart disease? Do I have to track to be successful? Do Women need carbs for hormone health?   Sponsors for this episode:  Wild Foods Co This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co!  This episode is sponsored by our Naturally Nourished Keto Reset Program. Ready to take the guesswork out of keto and finally see real results? Whether you're struggling with weight loss resistance, hormonal imbalances, gut issues, or just want more energy and less bloat—our Keto Reset program is your roadmap. You’ll get a structured, functional medicine approach that goes beyond macros and meal plans. We teach you why your body is stuck and how to heal it from the root—through nutrient-dense food, therapeutic tools, and behavior change strategies that last. You’ll be supported every step of the way with weekly classes and Q&As, downloads, real food meal plans, and direct access to us. This isn’t about restriction or gimmicks. It’s about learning to work with your body, building metabolic flexibility, and unlocking your best health. Doors are open now—so join us, reset your metabolism, and transform your relationship with food, your body, and your health. Grab your spot here.  

In this episode we celebrate the official release of the Naturally Nourished Kids Cookbook live with Naturally Nourished Podcast fans over a virtual party!  We address all of your burning questions about optimal eating for toddlers through teens! Learn about our personal process of writing, photographing, and publishing this cookbook.    In this episode we share our children's favorite recipes, how to get ample protein into your child, the importance of baby led weaning, why we aren’t a fan of grazing or excessive snacks, and more! We also share top ways to support your child’s immune system this season.   Links featured in this episode:  NN Kids Amazon Store https://www.amazon.com/shop/beckiyoord   Vanilla Bean Marshmallows https://www.youtube.com/watch?v=xp-tZg3OL_k   Special Thank You to our Naturally Nourished Kids Book Tour Sponsors! FOND Regenerative bone broth and tallow made from pasture-raised, regenerative farms. Rich & Nourishing. Slow-simmered with herbs, veggies, and spices. Pure & Organic. No additives or preservatives. Shop at FondRegenerative.com and use NATURALLY10 to save!   Wild Foods our favorite clean, purposeful food-as-medicine pantry staples to support your focus, energy, and balance. Shop at wildfood.co and use ALIMILLERRD to save!   Come see us on our book tour for in person events! Book tour link: https://alimillerrd.com/pages/nn-kids-book-tour   Baby Led Weaning podcast resource https://www.naturallynourishedrd.com/podcast/naturally-nourished-episode-239-baby-led-weaning/   Bonus guide including recipes, meal plan, and Immune Guide https://alimillerrd.com/pages/naturally-nourished-kids-bonus   Kids Essentials Bundle  https://alimillerrd.com/products/kids-essentials-bundle   Medicinal Honey w/ Cellular Antiox & Bio-C Plus https://www.youtube.com/watch?v=q7RZC8FyxkI Sponsor for this episode:  This episode is sponsored by Air Doctor.  The indoor air that we breathe can be up to 100 times  MORE polluted than outdoor air, according to the EPA. Indoor air pollutants can cause respiratory symptoms like sneezing, congestion, scratchy throat, and even more serious health problems like lung and heart disease. Introducing AirDoctor, the air purifier that filters out 99.99% of dangerous contaminants so your lungs don’t have to. This includes allergens, pollen, pet dander, dust mites, mold spores and even bacteria and viruses.AirDoctor comes with a 30-day money back guarantee so if you don’t love it, just send it back for a refund, minus shipping!Head to airdoctorpro.com and use promo code ALIMILLERRD and you’ll receive UP TO $300 off air purifiers! Exclusive to podcast customers, you will also receive a free 3 year warranty on any unit, which is an additional $84 value!   

  In this episode, we debunk the most common misconceptions about the ketogenic diet—from worries about gut health and restrictive eating, to concerns about processed foods, to whether keto is bad for women’s hormones and heart health. If you’ve been curious about keto but held back by these myths, we’re here to clear the air. You’ll learn how keto, when done right, can be a powerful therapeutic tool for healing the whole body, not just a passing fad or quick fix.  We also discuss our Keto Reset Program, a food-as-medicine approach designed to support sustainable health and metabolic balance. This episode highlights why our program stands apart by focusing on nourishing, whole foods and personalized guidance that fits your unique needs. Whether you’re new to keto or looking to deepen your understanding, this episode provides clarity and inspiration to take charge of your health with confidence.  Also in this episode:  Keto Reset Program - Starts 9/24! What is a keto reset? How our approach to mastering your metabolism is unique Naturally Nourished Episode 99 Ketosis As Medicine Busting Keto Myths Myth #1: Keto kills your microbiome because it lacks fiber Beat the Bloat Cleanse Phytofiber Myth #2: Keto is just a fad diet and you’ll gain all the weight back Two Year Clinical Trial Outcomes Provide Evidence for Long-Term Benefits of Virta for Type 2 Diabetes Myth #3: Keto is all processed and packaged What is Dirty Keto? And Why Real Food Matters - YouTube Myth #4: Keto wrecks your hormones Naturally Nourished Episode 190 Keto and Women's Hormones Episode 430: Keto and PCOS Relax and Regulate BroccoDetox Myth #5: Keto causes heart disease from all the saturated fat The effects of low-carbohydrate diet on glucose and lipid metabolism in overweight or obese patients with T2DM: a meta-analysis of randomized controlled trials - PMC Sponsors for this episode:  This episode is sponsored by our Naturally Nourished Keto Reset Program. Ready to take the guesswork out of keto and finally see real results? Whether you're struggling with weight loss resistance, hormonal imbalances, gut issues, or just want more energy and less bloat—our Keto Reset program is your roadmap. You’ll get a structured, functional medicine approach that goes beyond macros and meal plans. We teach you why your body is stuck and how to heal it from the root—through nutrient-dense food, therapeutic tools, and behavior change strategies that last. You’ll be supported every step of the way with weekly classes and Q&As, downloads, real food meal plans, and direct access to us. This isn’t about restriction or gimmicks. It’s about learning to work with your body, building metabolic flexibility, and unlocking your best health. Doors are open now—so join us, reset your metabolism, and transform your relationship with food, your body, and your health. Grab your spot here.

In this episode, we shine a spotlight on insulin—an often overlooked but crucial hormone that plays a central role in metabolism and overall health. While blood sugar gets a lot of attention, insulin is the key regulator behind it, influencing energy storage, fat metabolism, and cellular function. We explore how insulin resistance develops, the early signs to watch for, and why it’s so important to address this root issue to prevent chronic disease. We also discuss how ketogenic and low-carb diets can help regulate insulin levels, improve metabolic flexibility, and support weight management. This episode provides clear, functional insights into insulin’s role and practical strategies for balancing it through nutrition and lifestyle, making it a must-listen for anyone interested in metabolic health and disease prevention. Also in this episode:  Keto Reset Program - Enrollment opens 8/28! Episode 76 Getting to the root of insulin resistance What is insulin and why does it matter? What is insulin resistance? What causes insulin resistance? How does it develop on a cellular level?  What are signs and symptoms of insulin resistance? How do we test for insulin resistance? Fasting insulin <8 C-peptide – Reflects insulin production Glucose-insulin index / HOMA-IR – Measures insulin resistance directly (calculated using fasting glucose & fasting insulin)  Triglyceride:HDL ratio – Optimal <1.5 (higher = higher risk) A1c – Goal <5.5% (but early IR won’t always show up here) hs-CRP – Inflammation worsens insulin signaling Leptin Keto Checkup Lab (Fasting Insulin, A1c, Leptin, CMP, DHEA-s) Continuous Glucose Monitor Nutrisense use code ALIMILLLERD Conventional treatment of insulin resistance Naturally Nourished 323 Ozempic, Wonder Drug or Too Good to be True? Naturally Nourished Episode 359 Oh-No Ozempic Updates, Berberine and Keto Food as medicine for insulin resistance Ditch the drivers: eliminate refined carbs, sugar, seed oils, and artificial sweeteners Top 5 Benefits of Apple Cider Vinegar | Let's make an ACV shooter Cinnamon, turmeric, fenugreek Intermittent fasting Movement: Walking after meals Naturally Nourished Episode 424 How Daily Walking Can Transform your Health Keto for insulin resistance A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial - PubMed Ketogenic Diets for Body Weight Loss: A Comparison with Other Diets Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024 Supplements for insulin resistance Berberine Boost Relax and Regulate EPA DHA Extra Vitamin D Balanced Blend L-Carnitine ALA Chromium & Resveratrol Multidefense Sponsors for this episode:  This episode is sponsored by our Naturally Nourished Keto Reset Program. Ready to take the guesswork out of keto and finally see real results? Whether you're struggling with weight loss resistance, hormonal imbalances, gut issues, or just want more energy and less bloat—our Keto Reset program is your roadmap. You’ll get a structured, functional medicine approach that goes beyond macros and meal plans. We teach you why your body is stuck and how to heal it from the root—through nutrient-dense food, therapeutic tools, and behavior change strategies that last. You’ll be supported every step of the way with weekly classes and Q&As, downloads, real food meal plans, and direct access to us This isn’t about restriction or gimmicks. It’s about learning to work with your body, building metabolic flexibility, and unlocking your best health. Doors are open now—so join us, reset your metabolism, and transform your relationship with food, your body, and your health. Grab your spot here.