Uncommon Thinkers 2025: Solar spacecraft, sci-fi biology, destroying PFAS, beyond AI chatbots, and better social media

On this special episode of the GeekWire Podcast, recorded backstage at the GeekWire Gala at the Showbox Sodo, we sit down with five of the inventors, scientists, and entrepreneurs selected as the Seattle region's 2025 Uncommon Thinkers, in partnership with Greater Seattle Partners. Jeff Thornburg spent years building rocket engines for Elon Musk at SpaceX and Paul Allen at Stratolaunch. Now, as CEO of Portal Space Systems, he's moved past chemical rockets to revive a concept NASA studied decades ago but never pursued — a spacecraft powered by focused sunlight. He calls it a "steam engine for space." Read the profile. Anindya Roy grew up in rural India without electricity, came to the U.S. with two suitcases and $2,000, and earned a spot in the lab of a Nobel Prize winner. Now, as co-founder of Lila Biologics, he's using AI to design proteins from scratch (molecules that have never existed in nature) to treat cancer. Read the profile. Jay Graber runs Bluesky, the decentralized social network that's become a leading alternative to X and other centralized platforms. But while most tech CEOs build moats to lock users in, Jay and the Bluesky team are building a protocol designed to let them leave. She sees the network as a "collective organism," and she's creating a tech foundation meant to outlive her own company. Read the profile. Read the profile. Kiana Ehsani came to Seattle from Iran for her PhD and spent four years at the Allen Institute for AI before becoming CEO of Vercept. She and the Vercept team are competing directly with OpenAI, Google and others in AI agents, building efficient agents that handle mundane digital tasks on computers so humans can spend less time on screens. Read the profile. Brian Pinkard spent six months after college flipping rocks and building trails because he wanted to do work that mattered. That instinct led him to Aquagga, where he's proving that the industry standard of filtering and burying "forever chemicals" is obsolete. Instead, he's using technology originally designed to destroy chemical weapons to annihilate PFAS under extreme heat and pressure. Read the profile. Eagle-eyed readers may have noticed we're missing one honoree — Chet Kittleson, co-founder and CEO of Tin Can, the startup making WiFi-enabled landline phones to help kids connect without screens. Chet wasn't able to join us, but we plan to speak with him on a future episode. With GeekWire co-founder Todd Bishop. Edited by Curt Milton.See omnystudio.com/listener for privacy information.

Trevor Noah speaks with GeekWire's Todd Bishop after Noah taught a 5th grade class at Ardmore Elementary in Bellevue, Wash., for Code.org's Hour of AI during Computer Science Education Week. The former Daily Show host, comedian, author, podcast host, and Microsoft "Chief Questions Officer" talks about learning AI alongside kids, the importance of maintaining unbridled curiosity, and how artificial intelligence may — or may not — reshape the craft of comedy. RELATED STORY: ‘We are all kids in the age of AI’: Trevor Noah teaches 5th graders — and learns a few things himselfSee omnystudio.com/listener for privacy information.

Amazon is experimenting again. This week, we dig into our scoop on Amazon Now, the company's new ultrafast delivery service. Plus, we recap the GeekWire team's ride in a Zoox robotaxi on the Las Vegas Strip during AWS re:Invent. And in our featured interview, from the show floor, AWS Senior Vice President Colleen Aubrey discusses Amazon's push into applied AI, why the company sees AI agents as "teammates," and how her team is rethinking product development in the age of agentic coding. RELATED STORIES Stars on the ceiling, Cher on the speakers: Notes from our first ride in Amazon’s Zoox robotaxi Groceries in a flash: We tested ‘Amazon Now’ in Seattle — and got our delivery in 23 minutes AWS CEO Matt Garman thought Amazon needed a million developers, until AI changed his mind With GeekWire co-founders Todd Bishop and John Cook. Edited by Curt Milton.  See omnystudio.com/listener for privacy information.

What's the real value in AI tools — and what separates those who use them well from those who don't? Sam Ransbotham, professor of business analytics at Boston College and host of the "Me, Myself and AI" podcast from MIT Sloan Management Review, compares notes with GeekWire Podcast host Todd Bishop in a two-part collaboration between the shows. On this episode, they discuss the new digital divide emerging in the classroom, AI's measurement problem (and what Wikipedia teaches us about it), the "race to mediocre," how AI is democratizing startup creation, and the tension between AI productivity, time, and the moments that make us human. Find the rest of their conversation in the Me, Myself and AI podcast feed. See omnystudio.com/listener for privacy information.

This week: Jeff Bezos is back in startup mode (sort of) with Project Prometheus — a $6.2 billion AI-for-the-physical-world venture that instantly became one of the most talked-about new companies in tech. We dig into what his return to the CEO title really means, why the company’s location is still a mystery, and how this echoes the era when Bezos was regularly launching big bets from Seattle. Then we look at Amazon’s latest real-world experiment: package-return kiosks popping up inside Goodwill stores around the Seattle region. It’s a small pilot, but it brings back memories of the early days when Amazon’s oddball experiments seemed to appear out of nowhere. And finally…Todd makes the case for upgrading his 2007 Toyota Camry with CarPlay, Android Auto, and a backup camera — while John questions the logic of sinking thousands into a beloved older car. All that, plus a mystery Microsoft shirt, a little Seattle nostalgia, and a look ahead to next week’s podcast collaboration with Me, Myself and AI from MIT Sloan Management Review. With GeekWire co-founders John Cook and Todd BishopSee omnystudio.com/listener for privacy information.

This week: A glimpse of the AI frontier in workplace productivity through the eyes of David Shim — serial entrepreneur, Read AI co-founder and CEO, former Foursquare leader, and this year’s GeekWire Awards CEO of the Year. Shim spoke with GeekWire co-founder John Cook at a recent dinner event hosted in partnership with Accenture, in conjunction with our new Agents of Transformation editorial series, exploring AI, productivity, and the future of work. They discuss the rapid rise of workplace AI, why Shim believes today’s boom is fueled by real revenue rather than dot-com-style subsidies, and where he sees both hype and genuine value emerging. Shim offers insights on AI assistants, cross-team “multiplayer AI,” global adoption, and the controversial idea of “digital twins” built from employees’ work data. Recorded by Jessica Reeves; edited by Curt Milton. See omnystudio.com/listener for privacy information.

Seattle’s consumer-hardware ambitions are once again colliding with economic reality. The struggles of Glowforge and Rad Power Bikes echo a long regional history of big raises, high hopes, and hard landings — shaped by the pandemic, VC, and the unforgiving nature of building real products.  GeekWire co-founders Todd Bishop and John Cook recorded this conversation for the purpose of providing the audio to an AI tool that turned the conversation into a written column that was edited and reviewed before publication. Check it out here. Related Stories:  Glowforge hits restart: After restructuring, co-founders acquire key assets of laser engraver startup Rad Power Bikes faces possible shutdown as it tries to survive ‘significant financial challenges’ See omnystudio.com/listener for privacy information.

What’s it like to pitch your dream on Shark Tank, get rejected on national TV in front of eight million people — and then turn that failure into a company Amazon later buys for more than a billion dollars. Ring founder Jamie Siminoff did just that. A serial inventor and entrepreneur, Siminoff joins us to talk about his new book, Ding Dong: How Ring Went from Shark Tank Reject to Everyone’s Front Door (out Nov. 10), sharing the messy, high-stakes, and ultimately inspiring story behind the company. Now back at Amazon as a vice president leading Ring and the company’s home-security businesses, Siminoff reflects on failure, reinvention, and what comes next in the age of AI. Related links and stories Pre-order the book on Amazon. GeekWire: Ring founder Jamie Siminoff rejoins Amazon in new VP role Business Insider: Amazon VP says his division is hiring and promoting based on employees’ AI usage Inc.: The tech founder who wants to fix small-town America With GeekWire co-founder Todd BishopSee omnystudio.com/listener for privacy information.

Why is Amazon laying off 14,000 people during a massive AI boom? Todd and John analyze the Seattle tech paradox, digging into Andy Jassy's 'startup' reasoning and debating whether the AI frenzy is a bubble. Then, they take on the Cascadia high-speed rail: a necessary connector or a misguided project? Related headlines from the week Amazon layoffs Amazon confirms 14,000 job cuts, says push for ‘efficiency gains’ will continue into 2026 A tale of two Seattles in the age of AI: Harsh realities and new hope for the tech community Filing: Amazon cuts more than 2,300 jobs in Washington state as part of broader layoffs Amazon layoffs hit software engineers hardest in Washington Amazon layoffs reaction: ‘Thought I was a top performer but guess I’m expendable’ Amazon CEO says massive corporate layoffs were about agility — not AI or cost-cutting Amazon earnings Amazon stock soars 11% after topping Q3 estimates with $180B in revenue, $21B in profits Amazon’s Anthropic investment boosts its quarterly profits by $9.5B ‘Big Beautiful’ tax benefit: Amazon and other tech giants reap the rewards of new law, for now Microsoft Azure, earnings and OpenAI Microsoft’s Azure reports cloud outage, disrupting global customers including Alaska Airlines Microsoft beats expectations, reports nearly $35B in Q1 capital spending amid Azure outage Microsoft gets 27% stake in OpenAI, and a $250B Azure commitment Seattle-Portland-Vancouver Slowly but surely, high-speed rail backers believe Cascadia mega-project will become a reality Cascadia’s AI paradox: A world-leading opportunity threatened by rising costs and a talent crunch The ‘enormous barrier’ that threatens economic growth in the Pacific Northwest Beta’s unique electric airplane flies into Seattle to wow state officials and aviation experts With GeekWire co-founders John Cook and Todd BishopSee omnystudio.com/listener for privacy information.

From empty offices in 2020 to AI colleagues in 2025, the way we work has been completely rewired over the past five years. Our guest this week studies these shifts closely along with her colleagues at Microsoft. Colette Stallbaumer is the co-founder of Microsoft WorkLab, general manager of Microsoft 365 Copilot, and the author of the new book, WorkLab: Five years that shook the business world, and sparked an AI-first future, from Microsoft’s 8080 Books. With GeekWire co-founder Todd Bishop; edited by Curt Milton.See omnystudio.com/listener for privacy information.