Metabolic Health, Hormones, and the Liver: A Conversation with Amandine de Paepe

Kat Burki is a skincare expert and the founder of her eponymous clinical skincare line, known for its science-driven approach to skin health and regeneration. With a background in nutritional biochemistry, epidemiology, health law and disease management, her work sits at the intersection of nutritional science and topical skincare, focusing on how nutrient delivery can support the skin’s natural repair processes.Before launching her brand, Burki spent more than a decade developing health programs focused on the prevention and management of chronic illness. Her work centered on improving patient outcomes through a deeper understanding of inflammation, cellular health and the role nutrition plays in the body’s ability to repair and regenerate.Frustrated by the limitations of traditional cosmetic formulations, Burki began applying principles from clinical nutrition to skincare. She developed formulations designed to deliver high-performance nutrients directly to the skin, supporting cellular renewal and barrier repair. This philosophy became the foundation of Kat Burki Skincare, a line known for its focus on ingredient potency, bioavailability and advanced delivery systems.Today, Burki advocates for a more integrative view of skincare—one that recognizes the relationship between diet, inflammation, gut health and the skin’s ability to regenerate. Through her products and educational initiatives, she continues to explore how clinical nutritional science can be translated into topical skincare designed to support long-term skin health. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Julie de Libran is a renowned French fashion designer, celebrated for her refined and elegant approach to womenswear. Her career began at prestigious houses such as Gianfranco Ferré and Gianni Versace, before spending a decade at Prada, where she oversaw women’s ready-to-wear, made-to-measure, celebrity dressing, and lingerie collections, rising to design director and working closely with Miuccia Prada.She then moved to Louis Vuitton, serving for six years as creative director for women’s ready-to-wear and head of the design studio under Marc Jacobs. In 2014, de Libran became creative director of Sonia Rykiel, successfully blending modern sophistication with the brand’s playful spirit. In 2019, she launched her own responsible couture label, Julie de Libran Paris, focusing on craftsmanship, sustainability, and exclusivity. Known for rich textures, intricate tailoring, and timeless femininity, de Libran has earned a reputation for creating luxurious, wearable fashion for the modern woman. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Journaliste de formation, Julia a fait ses classes au sein de différentes rédactions de presse féminine avant de co-fonder le site Do It In Paris, devenu une référence incontournable des adresses et tendances parisiennes.Animée par une curiosité constante pour les lieux, les rencontres humaines et les marques, elle a ensuite lancé son agence de consulting, Supplément Chantilly, dédiée à l’accompagnement de marques niches dans leur développement stratégique, digital et commercial.De manière très naturelle, l’univers du bien-être s’est imposé à elle. Au fil des missions menées pour des marques du secteur, Julia a développé une approche de plus en plus connectée et intuitive. Profondément convaincue par la puissance de la guérison par le son, elle s’est formée auprès des meilleurs praticiens afin de pouvoir elle-même prodiguer des soins.En réunissant ses deux univers, la stratégie de marque et le soin, elle a créé Agua Sagrada, une marque de beauté holistique. Son premier produit, une huile parfumée destinée à rééquilibrer l’âme et l’esprit, s’appelle Buena Onda. Une invitation à être sur la bonne fréquence, celle que Julia s’efforce d’incarner et de transmettre chaque jour. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

To meet Pippa Small, you are immediately struck by the layers of jewellery which line her skin, glinting and jangling with every gentle movement. As she speaks, her hands will touch these bangles, rings and necklaces, as if they are treasured talismans which punctuate her point or give her reassurance. She has always understood jewellery as storied objects, lined with tales of inheritance, landscape, relationships and memory. Pippa has been making jewellery for as long as she can remember. Stones, shells and beads hunted and found to create handmade pieces which chronical her earliest adventures and experiences.Pippa holds an MA in Medical Anthropology, cultivating her interest in human rights amongst minorities, indigenous peoples and tribal groups through collaborations with grass roots organisations in Borneo, Thailand and India, amongst others. Pippa has won numerous awards for social responsibility, is an ambassador of the human rights organisation Survival International, and was awarded an MBE in 2013 for her ethical jewellery and charity work. Our first shop opened in Notting Hill, London in 2007, followed soon after by our shop in Santa Monica, California. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Lily Montasser is a personal essayist and cultural editor based in New York City. A writer and creative at heart, her work explores identity, taste, masculinity, and modern culture through a deeply personal lens.Originally from Big Sur, Lily brings a sense of introspection and natural perspective to her writing and styling work. In 2015, she founded The Demeler, a blog that became a formative platform for her voice, blending cultural commentary, personal narrative, and visual storytelling.Alongside her editorial work, Lily is a men’s stylist. She currently lives and works in NYC, where she continues to develop projects across writing, creative direction, and fashion. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Agatha Relota Luczo is the founder and CEO of Furtuna Skin, an Italian skincare line combining regenerative agriculture practices with modern science to drive unprecedented performance of its olive oil-based products. Agatha began her career at age sixteen, gracing the pages of Vogue, W, and L’Officiel and starring in campaigns for Chanel, YSL, and Hermès. As a model, Agatha worked with the most sought-after makeup artists, skincare experts, and physicians, acquiring an extensive understanding of products, ingredients, and regimens to help care for the skin and overall health and well-being. She parlays this knowledge into Furtuna Skin to drive the development of the brand’s award-winning, high-performance products. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Dans sa quête pour devenir maman, Amandine a traversé six fausses couches. Après de multiples consultations et traitements hormonaux, c’est un médecin qui, en approfondissant les analyses, a mis en lumière une cause trop souvent négligée. Un foie surchargé qui lui causait une résistance à l’insuline ainsi qu’une carence en vitamines liposolubles. Ces déficits, pourtant essentiel au bon fonctionnement de l’organisme, avait un impact direct sur sa fertilité. Cette révélation a profondément marqué Amandine. En tant que scientifique, elle y a vu bien plus qu’un cas personnel : un signal d’alerte sur un déséquilibre nutritionnel généralisé dans nos modes de vie modernes. Forte de sa formation en sciences biomédicales et en nutrition, elle décide alors de créer Insentials. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

I am so thrilled to share this podcast with Anna Numerologie. As we soon enter a year “1” in numerology, this could not be more fitting. Numbers speak to us through the sacred dimension and the intrinsic energies they carry. We all unconsciously associate ideas with the symbolism of each number, often without realizing it. For example, the symbolism of the number 1 evokes the individual, beginnings, the start of a new cycle, independence. The number 2 represents partnership and union. As for the number 7, this famous 7, found in so many religious texts, structuring the seven days of the week and referring to the seven musical notes and the seven chakras, it is associated with spirituality. Anna shares her story and how she created the “Code de réalisation personnel” aka your Code of Personal Fulfillment.If you are interested in going deeper, I definitely recommend getting a personal consultation with Anna or participating in this amazing event she is planning in January! It is an event called “2026: The Year of All Possibilities,” designed to break the year down in an ultra-detailed way so that everyone leaves with a clear, practical GPS to navigate the entire year. Sign up here: https://calendly.com/annanumerologie/atelier-numerologie-10-janvier?back=1&month=2026-01ENJOY,xx,JJThe Social Medium is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Xavière Laffont, journaliste chez Challenges pour la rubrique Luxes, XavièreLaffont est également en charge du compte @challenges.luxes. Après avoirfait ses armes au sein du groupe Le Figaro au service économie puis au seinde la rédaction du madame.lefigaro.fr, elle a dirigé durant plus de six ans larédaction du magazine ohmymag, un pureplayer de chez Prisma Media entant que rédactrice en chef puis directrice de la rédaction. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe

Business Women in Paris est un réseau fondé par Olivia Hayoun pour répondre à un besoin concret : offrir aux femmes entrepreneures un espace d’échanges libres, de réflexion et de soutien mutuel. Initialement conçu comme un petit cercle d’amies partageant leurs expériences, le projet s’est rapidement structuré pour devenir une véritable communauté animée par une même ambition — créer des connexions fortes et favoriser la progression de chacune dans un cadre bienveillant et stimulant.Forte d’une expérience de dix ans au sein de grands groupes du luxe, où elle a occupé des postes en achats, trade marketing et marketing opérationnel, Olivia a choisi de donner un nouveau sens à son parcours en cofondant Colette Lab, une marque de compléments alimentaires dédiée au positive-aging, inspirée de sa grand-mère.Convaincue que l’entrepreneuriat se nourrit de rencontres et de partages, elle a imaginé Business Women in Pariscomme un lieu d’inspiration, de collaboration et de croissance collective, où chaque femme peut s’exprimer, apprendre et faire évoluer son projet aux côtés d’autres entrepreneures engagées. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit jjchase.substack.com/subscribe