The Lens Newsletter: November 5, 2025

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:The incidence of sports-related orbital fractures in the U.S. has remained stable over the past decade, with baseball, cycling, and softball as leading causes.GLP-1 receptor agonist use in non-diabetic patients who are overweight or obese reduces risk of developing dry AMD.Changes in cup-to-disc ratio alone are unreliable for predicting glaucoma progression.Metformin protects against developing primary open-angle glaucoma in adults aged 40 years and older with diabetes.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:Pre-exposure prophylaxis nucleoside and nucleotide reverse transcriptase inhibitors found to be associated with an increased risk of primary open angle glaucoma.New study finds additional systemic drugs that could increase patient risk of macular toxicity.Retinopathy of prematurity is found to have a place-based association with a child’s neighborhood as measured by the childhood opportunity index.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…Corticosteroids and DMARDs together were found to be superior to corticosteroids alone in treating non-anterior sarcoid uveitis. Thousands of Americans have come to the ED over the past few years for pickleball-related ocular traumas, suggesting eye protection could be beneficial in this sport. Glaucoma is associated with sleep-wake and Circadian rhythm disorders, likely secondary to damage to the RGCs and optic nerve causing irregular regulation of sleep-wake physiology.Novel statin nanoparticles injected intravenously can preserve and even double cone photoreceptors in retinitis pigmentosa mouse models by reducing inflammation.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…A cohort study of NASA astronauts found that those who developed spaceflight-associated neuro-ocular syndrome during one long-duration mission were highly likely to develop it again on subsequent missions.Strabismus surgery is undervalued by Medicare, as evidenced by a surgical cost analysis underscoring the need for fair compensation to address the growing shortage of strabismus surgeons and ensure patient access to care.For acute acquired comitant esotropia, augmented medial rectus recession surgery achieved significantly better long-term eye alignment, fusion, and quality-of-life outcomes than botulinum toxin A injection.

In this episode, Dr. Sandra Lora Cremers joins us to explore the rising prevalence of dry eye disease and its impact on patients. We discuss how modern lifestyles and screen use are changing ocular surface health, the early warning signs not to overlook, simple and effective prevention strategies, and the innovative treatments shaping the future of dry eye care.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:Cultured corneal endothelial cell transplants maintained clear corneas and vision for up to 10 years, offering a scalable alternative to donor tissue.Long-term atropine use for myopia control showed no increased risk of cataract, glaucoma, or maculopathy in a nationwide cohort.Patients with giant cell arteritis had higher 5-year risks of aortic aneurysm and carotid stenosis, especially those with visual symptoms.Higher omega-3 fatty acid levels were linked to a significantly lower risk of developing primary open-angle glaucoma.

In this episode, Dr. David J Palmer, MD joins us as we dive into the topic of sustainability in ophthalmology. We explore three of the most environmentally pressing issues in ophthalmology today and hear about various studies, organizations, and resources that support efforts to make ophthalmology greener. 

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:The incidence of ocular surface squamous neoplasia in the US nearly tripled from 2014 to 2021.Trabeculectomy with mitomycin C fails more often in Hispanic patients.Ocular and orbital trauma in intimate partner violence identifies high-risk patients with elevated mortality, underscoring the need for early protective intervention.Swept-source AS-OCTA detects corneal vasoconstriction, showing reduced flow area and potential for monitoring neovascularization.Early-onset inherited retinal diseases show distinct refractive error shifts, highlighting the need for early screening and intervention.

In this episode, Dr. Puente joins us for a conversation about disability in ophthalmology from a clinical perspective - exploring successes, identifying gaps, and sharing lessons that can help shape more accessible eye care for the future.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode, we discuss:Asymmetric Multi-point Defocus Technique (AMDT) lenses reduced myopia progression in children compared with single-vision lensesThere was no improvement in vision with the addition of corticosteroids or corneal cross-linking in the treatment of bacterial keratitisTear cell-based assays had a greater sensitivity than serum in detecting ocular myasthenia gravisAntioxidant protein DJ-1 may be protective against the mechanisms behind diabetic keratopathy