VMAT2 Inhibitors: Valbenazine (Ingrezza) and Deutetrabenazine (Austeo)

Welcome back! Today we are featuring the two FDA-approved medications for tardive dyskinesia, the VMAT2 inhibitors Valbenazine (Ingrezza) and Deutetrabenazine (Austedo). References: https://pubmed.ncbi.nlm.nih.gov/41626799/https://www.ncbi.nlm.nih.gov/books/NBK548187/https://pubmed.ncbi.nlm.nih.gov/41626799/

We are back with another special guest episode! Please welcome Dr. Allen Frances, who was intricately involved in the formation of both the DSM III and DSM IV, the latter of which he served as chair.https://x.com/AllenFrancesMDhttps://www.amazon.com/stores/author/B001HO76FUhttps://www.psychiatrictimes.com/authors/allen-frances-md

Welcome back! Today we will be doing a brief episode on Topiramate [Topamax], and its clinical uses in psychiatry.References:https://pubmed.ncbi.nlm.nih.gov/21438989/https://pubmed.ncbi.nlm.nih.gov/18774432/https://pubmed.ncbi.nlm.nih.gov/25899459/https://pmc.ncbi.nlm.nih.gov/articles/PMC1088011/https://pmc.ncbi.nlm.nih.gov/articles/PMC2671954/https://pubmed.ncbi.nlm.nih.gov/38706338/https://pubmed.ncbi.nlm.nih.gov/20207521/

Welcome back, today we are discussing a deceptively difficult topic: What makes something a psychiatric illness? We are joined by our guest Dr. Mark Ruffalo. He is a psychotherapist in private practice in Tampa, FL, and who also serves as Assistant Professor of Psychiatry at the University of Central Florida College of Medicine as well an Adjunct Assistant Professor of Psychiatry at Tufts University School of Medicine. Dr. Ruffalo's Website: https://www.drruffalo.com/Dr. Ruffalo's LinkedIn: https://www.linkedin.com/in/mark-l-ruffalo-71929063PRISM: https://www.psychiatrictimes.com/view/use-of-the-prism-diagnostic-instrument-in-clinical-practicePRISM Writing Contest: https://www.psychiatrictimes.com/view/prism-writing-contest-more-on-this-new-diagnostic-tool-from-mark-ruffalo-msw-dpsa

Welcome back! Today we are at the highly prescribed and popular benzodiazepine Lorazepam, also known as Ativan. We look at its uses in psychiatry, especially catatonia. But despite anecdotal efficacy, does the evidence hold up? References:https://www.ncbi.nlm.nih.gov/books/NBK532890/https://pubmed.ncbi.nlm.nih.gov/36805317/https://pubmed.ncbi.nlm.nih.gov/6120058/https://pubmed.ncbi.nlm.nih.gov/10229064/https://psychopharmacologyinstitute.com/section/catatonia-diagnosis-the-lorazepam-challenge-2911-5899/

Welcome back! Today we are embarking into the first of hopefully several episodes on the importance of vitamins and minerals in mental health. We will specifically be looking at the role of iron deficiency in psychiatry and do an overview on some of the recent research that's been published. References: https://www.ncbi.nlm.nih.gov/books/NBK557376/https://www.sciencedirect.com/science/article/pii/S0268960X25000827#bb0165https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2823909https://www.sciencedirect.com/science/article/pii/S1389945717315599https://pubmed.ncbi.nlm.nih.gov/40841680/https://pubmed.ncbi.nlm.nih.gov/1677067/https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00463-7/fulltexthttps://pmc.ncbi.nlm.nih.gov/articles/PMC6139360/

Welcome back! Today our topic is Nutritional Psychiatry and we've invited a special guest - Dr. Laura Lachance, who has done extensive research in the field. Along with Dr. Drew Ramsey, she has published a paper looking at an Antidepressant Food Score or AFS and more recently, she was a part of the EASe-GAD trial, a study looking at the impact of omega-3 fatty acids on anxiety. Antidepressant Food Scale (AFS): https://pubmed.ncbi.nlm.nih.gov/30254980/EASe-GAD Trial: https://pubmed.ncbi.nlm.nih.gov/39316026/Gluten and Psychosis: https://pubmed.ncbi.nlm.nih.gov/24368154/Nutrition Worksheet for Patients: https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-021-03575-7Dr. Lachance's Instagram: https://www.instagram.com/preventivepsychiatry/

Welcome back! Today, we are hosting the highly accomplished Dr. Robert Sapolsky, PHD, a professor of professor of biology, neurology, and neurosurgery at Stanford University. He has had extensive research particularly in the field of neuroendocrinology and chronic stress, which has acted as one of the foundations of modern psychoneuroendocrinology. He is also a research associate at the Institute of Primate Research in Kenya, with over 30 years of field research in Africa. He is also a renowned author, with major works including but not at all limited to Why Zebras Don’t Get Ulcers, Behave: The Biology of Humans at Our Best and Worst, and most recently, Determined: A Science of Life Without Free Will, which challenges us to reconsider free will, morality, and mental health itself through a scientific lens. More about Dr. Sapolsky: https://en.wikipedia.org/wiki/Robert_SapolskyDr. Sapolsky's Open Stanford Course: https://www.youtube.com/watch?v=-PpDq1WUtAw&list=PL848F2368C90DDC3DDr. Sapolsky's Books: https://www.amazon.com/stores/author/B000APOCFEDr. Sapolsky's Own Podcast: Spotify: https://open.spotify.com/show/0wDrkkznSB8S84kKuK9HCoApple: https://podcasts.apple.com/us/podcast/robert-sapolsky-father-offspring-interviews/id1782280922

One hundred episodes later, let’s take it back to one of our very first, the Selective Serotonin Reuptake Inhibitors - with a much-needed update. Thank you to our guests, fans, and listeners.References: https://pmc.ncbi.nlm.nih.gov/articles/PMC4428540/ https://pubmed.ncbi.nlm.nih.gov/10333979⁠⁠https://pmc.ncbi.nlm.nih.gov/articles/PMC3663330/⁠

Welcome back! Today we have a very special episode on Alprazolam, brand-name Xanax. This benzodiazepine is one of the most commonly-prescribed and sought out psychotropic medications. https://www.ncbi.nlm.nih.gov/books/NBK538165/https://pmc.ncbi.nlm.nih.gov/articles/PMC6769182/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5846112/https://pubmed.ncbi.nlm.nih.gov/6141930/https://pubmed.ncbi.nlm.nih.gov/17514187/