Tiziana completes enrollment for Phase 2 trial in progressive MS study

Aftermath Silver CEO Ralph Rushton joined Steve Darling from Proactive to announce additional assay results from the company’s Phase 3 diamond drill program at the Berenguela silver-copper-manganese deposit located in the Department of Puno in southern Peru. Rushton explained that the latest results are based on 19 drill holes from the ongoing 90-hole diamond drilling campaign. The drilling program is primarily focused on infill work along a 225-metre strike length across two key zones within the existing resource area. The goal of the campaign is to better define higher-grade mineralization suitable for potential early-stage mining opportunities while also improving geological understanding of the broader deposit. The company is targeting several important objectives through the current drill campaign, including delineating high-grade zones that may support initial mining activities and refining the geological model for future planning and development work. To date, Aftermath Silver has completed approximately 15,540 metres of core drilling across three phases of activity. Management noted that assay results from approximately 15 additional holes remain outstanding and are expected to be reported in future updates. Rushton added that copper results from the latest holes have also been encouraging and could provide additional benefits to the project’s economics through potential future production scenarios. The company also reported that infill drilling across Domains 1 and 2 of the current mineral resource estimate has now been completed. Drilling activities have temporarily shifted to additional geotechnical work designed to support the ongoing pre-feasibility study currently underway. This work is being supervised by local Peruvian engineering company Amphos 21. Beyond the existing resource footprint, exploration activity continues to generate additional targets. The company noted that drilling has also identified high-grade copper mineralization near the eastern portion of the resource area where road construction is planned. In addition, sampling within the Southwest Intrusive/Skarn target area returned anomalous copper mineralization associated with silicified limestone over an approximate two-kilometre strike length. Management believes the combination of resource expansion potential, higher-grade mineralization targets, and ongoing engineering work continues to strengthen the long-term development outlook for the Berenguela project. #proactiveinvestors #aftermathsilverltd #tsxv #aag #otcqx #aagff #mining #BerenguelaProject #SilverProject #CopperProject #Manganese #PreFeasibilityStudy #PFS #MiningDevelopment #PeruMining #Mining #Silver #Exploration #ResourceDevelopment #MiningStocks #CriticalMinerals

American Resources Corp CEO Mark Jensen joined Steve Darling from Proactive to announce that its affiliated company, ReElement Technologies, has formed a joint venture with POSCO International Corporation to develop an integrated rare earth element and permanent magnet production platform in the United States. Jensen explained that the new joint venture represents an important milestone in strengthening the long-term partnership between ReElement and POSCO International. The collaboration builds upon a commercial offtake agreement announced previously and further reinforces efforts to enhance U.S.–South Korea cooperation in developing resilient supply chains for critical minerals used across national security, clean energy, and advanced technology industries. The companies intend to establish a fully integrated, closed-loop rare earth ecosystem designed to support the full value chain. This includes feedstock sourcing, separation, purification, refining, and permanent magnet manufacturing operations within the United States. The initiative is aimed at reducing dependence on foreign supply chains while helping create domestic capacity for strategically important materials. The partnership combines ReElement’s proprietary chromatography-based separation and purification technologies with POSCO International’s extensive industrial infrastructure, manufacturing capabilities, and global commercial relationships. ReElement’s refining platform is designed to produce high-purity rare earth oxides used across a broad range of sectors including electric vehicles, advanced manufacturing, defense technologies, and industrial applications. Management believes the combination of technical expertise and international industrial scale provides a strong foundation for accelerating deployment and commercialization. The companies also noted that POSCO International brings deep relationships throughout automotive and industrial markets, complementing ReElement’s focus on advanced material science and refining innovation. The joint venture is expected to support an estimated $200 million investment to establish a U.S.-based rare earth refining and permanent magnet manufacturing complex. Final site selection for the facility is currently underway. Development is expected to occur in phases, with initial plans targeting approximately 3,000 metric tonnes per annum of separated rare earth oxides during the first phase, followed by expansion plans that could increase production capacity to approximately 6,000 metric tonnes annually in later stages. Management believes the project represents a meaningful step toward strengthening North American critical mineral independence while supporting long-term demand growth for rare earth materials used in electrification and next-generation technologies. #proactiveinvestors #americanresourcescorporation #nasdaq #arec #ReElementTechnologies #ReElement #RareEarths #CriticalMinerals #POSCO #SupplyChain #CleanEnergy #AdvancedManufacturing #MiningStocks

Rockfire Resources PLC (LSE:ROCK) chief executive David Price talked with Proactive's Stephen Gunnion about the company’s Molaoi project in Greece and why the asset is becoming increasingly important within Europe’s critical minerals supply chain. Price explained that while Molaoi is primarily a zinc project, the company is placing growing emphasis on the germanium contained within the deposit. He described germanium as “quite a valuable byproduct at this stage,” highlighting its importance in semiconductors, automotive technology and military applications. Price discussed the strategic advantages of operating in Greece, describing the country as a safe and mining-friendly jurisdiction with established underground mining expertise. He also pointed to Europe’s increasing focus on securing domestic supplies of critical minerals, noting that Rockfire could become an important future supplier of germanium to the region. Price said: “Rockfire is in a great position for that,” when discussing Europe’s need for a secure germanium supply. The discussion also covered recent drilling activity at Molaoi, where holes HMO-015, HMO-016 and HMO-017 returned strong zinc, silver and germanium mineralisation. Price noted that recent results demonstrated both strong grades and continuity across the system, while ongoing drilling aims to upgrade the resource from inferred to indicated status. Price outlined upcoming catalysts for investors, including continued assay results, progress toward feasibility studies and the acquisition of the company’s own drill rig to improve operational flexibility. Watch the full interview for more insights into Rockfire Resources’ strategy, drilling progress and the growing importance of germanium in global markets. Visit Proactive’s YouTube channel for more videos, give this video a like, subscribe to the channel and enable notifications for future content. #RockfireResources #DavidPrice #Germanium #CriticalMinerals #Zinc #Silver #Mining #EuropeMining #GreeceMining #MineralExploration #ResourceStocks #BatteryMetals #CommodityMarkets #Investing #ProactiveInvestors

1911 Gold Corporation CEO Shaun Heinrichs joined Steve Darling from Proactive to announce significant development progress at the company’s True North Mine in southeastern Manitoba as it advances toward planned test mining later this year and full production targeted for 2027. The company confirmed that underground development crews have begun drift development on Level 16 at True North, marking an important operational milestone in the restart of mining activities. Management said development efforts are progressing steadily as the project moves closer to its planned test mining phase in 2026. The L10 and Hinge zones remain the primary focus of current activities, as both areas are expected to provide key operational and geological data needed to refine mine planning and support future production activities. These zones were selected because they will help reconcile existing block models and optimize the longitudinal narrow-vein mining methods planned for the operation. During the first quarter of 2026, underground predevelopment activities progressed on multiple fronts as the company established the infrastructure needed to support a return to active mining. Work completed included ongoing dewatering operations, upgrades to electrical and ventilation systems, installation of communications infrastructure, ground support rehabilitation, re-establishment of refuge stations, inspection and repair of blasting systems, and equipment procurement and maintenance. A key milestone was achieved with the completion of rehabilitation work on the second egress route connecting Level 16 to surface, a critical safety and operational requirement for resuming underground mining activities. Following the successful lowering of initial equipment underground, development officially commenced at the end of April in the L10 Zone, which hosts higher-grade mineralization accessible from Level 16. Current work includes ramp construction for stope access, sill drive development to expose and better define modeled vein structures, and installation of supporting infrastructure including ventilation systems, level access points, and remuck bays. Initial development efforts are focused on completing approximately 140 metres of ramp access into the L10 target area, supporting future drill bays for infill and delineation drilling programs. Meanwhile, delineation drilling on the lower portion of the Hinge Zone has now been completed, with stope planning and mine design currently being finalized. The company also announced that an underground development contract has been awarded, with mobilization expected in June 2026. The addition of a dedicated contract mining team is anticipated to accelerate development and support the company’s test mining timeline. In parallel with underground work, a diamond drill program has commenced across several targets in the upper Hinge Mine area. Up to five potential test mining targets are currently under evaluation, with three already rehabilitated and prepared for infill and delineation drilling. #proactiveinvestors #1911goldcorporation #1911gold #tsxv #aumb #otcqx #aumbf #GoldExploration #TrueNorthMine #GoldMining #TrueNorthProject #GoldExploration #Mining #ManitobaMining #Drilling #ResourceExpansion #JuniorMining

Eloro Resources Ltd Senior Vice President of Corporate Development Chris Holden joined Steve Darling from Proactive at the company’s OTC studio in New York City to discuss ongoing development at the Iska Iska polymetallic project in southern Bolivia and the company’s plans for a significant resource expansion program. Holden explained that the Iska Iska project hosts a broad suite of minerals, including zinc, lead, silver and tin, while also containing critical minerals such as antimony, indium and bismuth. He highlighted the growing strategic importance of these materials as governments and industries increasingly focus on securing stable supply chains for critical resources. The discussion centered on the substantial amount of exploration work already completed at the project and the considerable upside still remaining. To date, Eloro Resources has completed approximately 120,000 metres of drilling at Iska Iska, building a large geological database and helping define the scale of the mineralized system. Despite the extensive drilling completed so far, Holden emphasized that the deposit remains only partially tested. He noted that current exploration has covered only about 30% to 40% of the broader system, leaving considerable room for additional discoveries and resource expansion. The company’s next phase includes an ambitious 40,000-metre drilling campaign focused on expansion and step-out drilling. The objective is to significantly increase the current indicated resource, which management said stands at approximately 85 million tonnes, with a goal of potentially growing the resource base toward more than 140 million tonnes. Eloro is also advancing toward important development milestones. Management expects to complete a preliminary economic assessment (PEA) later this year, while pre-feasibility work is targeted for the following year as the project continues to move toward a more advanced development stage. Holden also discussed Bolivia’s broader mining landscape, describing the country as relatively underexplored compared with neighboring South American jurisdictions despite its strong geological potential. He added that the U.S. investment market continues to play an increasingly important role for Eloro Resources as interest in critical minerals rises and the company expands its North American shareholder base. #ProactiveInvestors #EloroResources #tsx #elo #otcqx #elrrf #IskaIska #CriticalMinerals #Silver #Zinc #Mining #BoliviaMining #ResourceExpansion #MiningStocks

Tiziana Life Sciences CEO Ivor Elrifi joined Steve Darling from Proactive to announce that patient enrollment has been completed in the company’s randomized, double-blind, placebo-controlled Phase 2 clinical trial evaluating intranasal foralumab in patients with non-active Secondary Progressive Multiple Sclerosis (na-SPMS). The company expects topline data from the study in the third quarter of 2026. In addition, findings from the trial are scheduled to be presented at the Joint Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) and ECTRIMS meeting in Toronto in October 2026. The trial represents the first Phase 2 placebo-controlled evaluation of intranasal foralumab and marks an important step in the development of what the company describes as a novel anti-CD3 monoclonal antibody platform targeting neurodegenerative and neuroinflammatory diseases. The multicenter study enrolled 48 participants across multiple leading U.S. sites, with patients receiving either intranasal foralumab or placebo over a 12-week treatment period. The study includes a broad range of assessments designed to evaluate both safety and efficacy, including PET imaging to examine microglial activation, MRI analysis, and comprehensive clinical evaluations. Patients who complete the blinded phase of the study will also have the opportunity to continue treatment in a six-month open-label extension phase designed to evaluate longer-term safety and sustained therapeutic benefit in the na-SPMS patient population. Management said completion of enrollment marks an important milestone in advancing the clinical program and reinforces the company’s commitment to addressing significant unmet needs in progressive neurological disorders. The company believes the study could provide important insights into whether intranasal foralumab may help regulate immune system activity and address neuroinflammation, potentially opening a new treatment pathway for patients living with progressive multiple sclerosis. #proactiveinvestors #tizianalifescienceslts #nasdaq #tlsa #newceo #ivorelrifi #Foralumab #SPMS #Biotech #ClinicalTrials #Neuroimmunology #HealthcareInnovation #DrugDevelopment #MedTech #MultipleSclerosis #MSResearch #Biotech #ClinicalTrials #Neurology #Healthcare #DrugDevelopment #Pharma

Gemdale Gold Executive Chairman Patrick Chidley joined Steve Darling from Proactive at the company’s OTC studio in New York City to discuss Gemdale Gold’s exploration strategy in Finland, recent market milestones, and progress at its flagship Pontio project. Chidley explained that Gemdale Gold recently listed on the TSX Venture Exchange under the symbol GEMG and has also secured an OTC listing in the United States under GDGIF. He noted that the company currently controls approximately eight years of exploration permits across Finland, providing a substantial land position focused on both gold and critical minerals opportunities. A major focus of the discussion was the company’s Pontio project, which Chidley described as a potentially significant large-scale gold discovery opportunity in Finland. Exploration activity at the property has progressed steadily, with approximately 10,000 metres of drilling completed to date. According to Chidley, roughly half of the company’s current 6,000-metre drill campaign has now been completed. “We’ve just finished nearly 5,000 metres of that program. We’ll be evaluating the results in the next couple of months,” Chidley said. He added that the current drill campaign is expected to support a maiden resource estimate for Pontio, which management believes could become a meaningful milestone in defining the scale and value of the project. Beyond Pontio, Gemdale Gold continues advancing a broader portfolio of exploration assets throughout Finland. Chidley highlighted additional projects in northern and southeastern regions of the country, including the Isoneva project located approximately 60 kilometres south of Pontio. The company plans to continue geological, geochemical, and drilling programs across these assets later this year. Chidley also emphasized Finland’s reputation as a mining-friendly jurisdiction with established infrastructure and a long history of resource development. He noted that the country's supportive environment continues to make it attractive for exploration investment and long-term project development. The interview also addressed the importance of expanding the company’s profile in U.S. markets. Chidley noted that several board members and shareholders are based in the United States, making the OTC listing an important component of Gemdale Gold’s broader market and capital strategy. #proactiveinvestors #gemdalegold #tsxv #gemg #otcqb #gdgif #Gold #FinlandMining #CriticalMinerals #Exploration #Drilling #MiningStocks #ResourceInvesting #GoldStocks

Metals One CEO Daniel Maling joined Steve Darling from Proactive at the company’s OTC studio in New York City to discuss Metals One’s strategy of building a diversified portfolio centered on gold, uranium, and AI-critical metals assets, while expanding its presence within the U.S. investment market. Maling outlined the company’s business model as a project identifier, financier, and developer focused on assembling high-potential assets across multiple commodity sectors. He explained that the company’s recent OTC Markets listing represents an important step in broadening visibility and attracting a larger North American investor audience. During the discussion, Maling highlighted Metals One’s involvement with Lions Bay Resources and its acquisition of a South African gold asset containing an estimated two million ounces of gold. The project is currently progressing through regulatory approvals, with management targeting advancement toward potential production later this year. Maling emphasized the company’s current strategic focus on gold and uranium, identifying both sectors as key long-term investment themes supported by strong market fundamentals. He noted that Metals One is actively concentrating capital and resources around these commodity opportunities as demand dynamics continue to evolve. The interview also focused on the company’s uranium exposure through NovaCore Uranium and its Red Basin project in New Mexico. Maling said drilling activity is expected later this year and noted that the company has already seen meaningful appreciation in the project’s value since its initial investment. He added that NovaCore is targeting a potential listing on the UK market later this year, a development that could allow Metals One to retain a carried interest through future exploration and drilling programs. Beyond gold and uranium, Metals One continues advancing a broader pipeline of opportunities, including exploration work at Swales Mountain and uranium recovery initiatives in Colorado using slurry waste recovery technologies. Maling also stressed the growing importance of the U.S. market for the company, noting that a combination of domestic project exposure and increased market visibility is generating stronger investor interest. He expressed confidence in the company’s outlook, citing favorable commodity themes, a strong funding position, and a steady pipeline of project catalysts expected to drive news flow in the months ahead. #proactiveinvestors #metalsone #aim #met1 #otcqb #mtopf #Gold #Uranium #CriticalMinerals #Mining #ResourceInvesting #AI #EnergyTransition #MiningStocks

Star Gold Corp CEO Lindsay Gorrill joined Steve Darling from Proactive’s OTC studio in New York City to provide an update on the company’s progress toward production at its Longstreet gold project in Nevada following a significant regulatory milestone. Gorrill explained that Star Gold has received approval from the United States Forest Service for its final plan of operations, a key step as the company advances toward securing its final production permit. Management views the approval as a major catalyst that moves the project substantially closer to development and production. During the discussion, Gorrill outlined the origins of the Longstreet project and explained how the company recognized an opportunity after uncovering historical feasibility work dating back to the 1980s. Since then, Star Gold has undertaken extensive development work, including drilling campaigns, environmental and biological studies, archaeological assessments, and permitting activities designed to position the asset for advancement. Gorrill emphasized the strategic advantages of operating in Nevada, one of the world’s most established mining jurisdictions, citing the state’s long mining history, experienced workforce, and generally supportive regulatory framework. He also noted that Longstreet falls within a small mine permitting structure, which may allow for a more streamlined approval process compared with larger-scale operations. Management believes the recent approval represents an important turning point for the company, allowing it to focus on securing the remaining production authorization while accelerating development efforts. Gorrill described the current stage as “full speed ahead” toward obtaining the final permit. Beyond Longstreet, the company also outlined broader growth objectives that include continued drilling and exploration at three additional targets within its portfolio. Star Gold intends to use future production cash flow to help fund expansion opportunities and support long-term shareholder value creation. The conversation also touched on current gold market conditions and the company’s efforts to broaden visibility among U.S. investors through participation in OTC Markets events and investor outreach initiatives in New York. #proactiveinvestors #stargoldcrop #otcqb #srgz #mining #ProactiveInvestors #StarGold #GoldMining #NevadaMining #Gold #Mining #Exploration #ResourceDevelopment #MiningStocks #GoldStocks

Cygnus Metals CEO Nick Kwong joined Steve Darling from Proactive’s OTC studio in New York City to provide an update on the company’s flagship Chibougamau copper-gold project in northern Quebec and discuss encouraging results from its latest drilling campaign at the Golden Eye deposit. Kwong explained that Cygnus Metals is advancing a brownfields copper and gold project that benefits from existing infrastructure, established mining history, and significant exploration upside. He emphasized that one of the project’s major advantages is the strong support received from regional stakeholders, including the Ouje-Bougoumou First Nation, the nearby mining town of Chibougamau, and the Quebec government, all of which have historically supported mining activity in the region. The discussion focused heavily on the company’s recent winter drilling campaign at the Golden Eye deposit, where Cygnus successfully completed drilling from ice pads positioned directly above the target area. According to Kwong, the results have significantly changed management’s view of the project's potential. He described Golden Eye as an important development for the broader asset, noting that recent drill results returned strong high-grade gold mineralization. Highlights included an intercept of 11 metres grading 4.3 grams per tonne gold, reinforcing the potential for a meaningful gold-rich component within the Chibougamau project area. The proximity of this mineralization to existing processing infrastructure further strengthens its potential economic attractiveness. Cygnus Metals also continues to advance exploration work across additional targets including Gwillim and Joe Mann, as the company evaluates opportunities to expand gold resources amid a strong precious metals pricing environment. Kwong said Chibougamau remains the company’s highest-priority asset because of its combination of infrastructure access, development economics, and district-scale exploration opportunity. The interview also highlighted increasing investor interest in the company following greater visibility through its OTC market presence and participation at the SME conference in New York, which management believes has helped broaden awareness of the company and its development strategy. #proactiveinvestors #cygnusmetals #asx #cv5 #tsxv #cyg #otcqb #ctggf #CopperExploration #GoldMining #LithiumStocks #QuebecMining #CriticalMetals #DrillResults #MiningStocks #ResourceInvesting #TSXV #ASXStocks #OTCMarkets #ErnestMast #ProactiveInvestors