Promethazine

Trade: MorphineClass: Opiate agonist/Narcotic Analgesic MOA: Binds to the opiate receptors. Reduces stimulation of the sympathetic nervous system caused by pain and anxiety. Reduction of sympathetic stimulation reduces heart rate, cardiac work, and myocardial O2 consumptionIndications: moderate to severe pain including chest pain associated with ACS, CHF, and pulmonary edema.Contraindications: Respiratory depression, shock.Side effects: Respiratory depression, hypotension, N/V, dizziness, lightheadedness, sedation, diaphoresis, euphoria, seizures, cardiac arrest, anaphylactoid reaction.Dosage:Adult  2-10mg IV/IO/IMPediatric < 110 lbs 0.025 – 0.2mg/kg IV/IO/IM

Trade: SublimazeClass: Narcotic Analgesic MOA: Binds to opiate receptors producing analgesia and euphoriaIndication: PainContraindication: Use caution in traumatic brain injury, Respiratory depression Side effects: Respiratory depression, apnea, hypotension, N/V, dizziness, sedation euphoria, Sinus bradycardia, sinus tachycardia, palpitations, HTN, diaphoresis, syncopeDosingAdult 50-100mcg IM/IVPedi 1-2mcg/kg IM/IV

Trade: Tegretol Class:  Anticonvulsant MOA: Binds preferably to voltage gated Sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.Indications: Partial and generalized tonic – clonic seizures Contraindications: AV Block, bundle branch block, agranulocytosis, bone marrow supression, monoamine oxidase inhibitor therapySide effects: Dizziness, drowsiness, ataxia, N/V, blurred vision, confusion, headache, transient diplopia, visual hallucinations, life threatening rashes.Dosing:Adult:200mg POPediatric:6-12 years old: 100mg PO        Less then 6: 10mg/kg PO

Trade: Toradol Class: NSAIDMOA: inhibits the production or prostaglandins in inflamed tissue, which decreases the responsiveness of pain receptors. Indications: Moderately severe acute painContraindications: Patients with a hx of peptic ulcer disease or GI bleed, patients with renal insufficiency, hypovolemic patients, 3rd trimester pregnancy, nursing mothers, allergy to other nsaids, stroke or head trauma, having surgery within the next 7 days.  Side effects:  headache, drowsiness, dizziness, abdominal pain, dyspepsia, N/V, Diarrhea.Dosing:Adult IV 30mgIM 60mg Senior (65 and older)/ Pediatric < 50kgsIV 15mgIM 30mg

Trade: Valium Class: BenzodiazepineMOA: Binds to the benzodiazepine receptor and enhances the effects of GABAIndications: Anxiety, Skeletal muscle relaxation, anticonvulsant Contraindications: Children younger then 6 months, acute angle glaucoma, CNS depression, alcohol intoxication. Side effects:  Respiratory depression, drowsiness, fatigue, headache, pain at the injection site, confusion, nausea, hypotension, cardiac arrest at high doses•Dosing:Adult: Anxiety: 2-10mg IV/IMSeizure: 5-10mg IV/IOPediatric:Anxiety: 0.2 – 0.3mg/kg IV/IMSeizure:  Older then 5 years: 1mg IV/IOOlder then 30 days less then 5 years: 0.2 to 0.5mg IV/IO                Neonate: 0.1-0.3mg/kg IV/IO

First and foremost, THANK YOU to everyone who was listened to this Podcast over the past year. In just under 12 months we have risen to one of the top listened to and searched paramedic pod casts on spotify and apple podcasts. Again, thank you so much!If you love listening to my voice read these drugs, but want an extra visual aid to go along with it, my classmate is currently selling laminated, professionally printed copies of every drug we have covered. They are  available one etsy RIGHT NOW! Head over there, check them out, and if you think they'll help, place an order. He will be running a discount exclusively for listeners of Paramedic Drug Cards for a limited time. Dont miss out!www.paramedicstudents.etsy.comExclusive DISCOUNT CODE for my listeners: MEDIC22

Trade – PhenerganClass – Antiemetic MOA - Decreases nausea and vomiting by antagonizing H1 receptors Indications – Nausea/Vomiting Contraindication – Altered level of consciousness, jaundice, bone marrow suppression, Use caution in seizure disorder.Side effects – Paradoxic excitation in children and older adults. Dosing:Adult - 12.5 - 25mg IV, IO, IMPedi - 2years and older 0.25 – 1 mg/kg IV, IO, IM 

Trade – CortefClass – Corticosteroid MOA – Reduces inflammation by multiple mechanisms. As a steroid it replaces the steroids that are lacking in adrenal insufficiency.Indications – Adrenal insufficiency, allergic reactions, anaphylaxis, asthma, COPDContraindications – Cushing Syndrome, known sensitivity to benzyl alcohol, Use with caution in diabetes, HTN, CHF, known systemic fungal infection, renal disease, idiopathic thrombocytopenia, psychosis, seizure disorder, GI disease, glaucoma. Side effects – Leukocytosis, hyperglycemia, increased infection, decreased wound healing, increased rate of death from sepsis.  Dosing Anaphylactic shock Adult 100-500mg IV,IO, or IM Pedi 2-10 mg/kg per day IV,IO, or IM max 500mg 

Trade – ApresolineClass – Vasodilator MOA – Directly dilates peripheral blood vesselsIndication – HTN associated with preeclampsia and eclampsia, HTN crisis Contraindication – Patients taking diazoxide or MAOI’s, coronary artery disease, stroke, angina, dissecting aortic aneurism, mitral valve and rheumatic heart disease. Side effects – Headache, angina, flushing, palpitations, reflex tachycardia, anorexia, N/V, diarrhea, hypotension, syncope, peripheral vasodilation, peripheral edema, fluid retention, pareshesias. DosingPreeclampsia and eclampsia:         Adult : 5-10mg IV repeat every 20-30mins until Systolic pressure of 90-105mmhgAcute HTN ( not associated with preeclampsia )        Adult :10-20mg IV/IM        Pedi : 1mo – 12yr  0.1-0.2 mg/kg IV/IM max 20mg per dose

Trade – CardeneClass – Calcium Channel blocker MOA – Blocks calcium movement into the smooth muscle of the blood vessel walls, causing vasodilation.Indication – Angina, HTNContraindication – Aortic stenosis, hypotension, use caution in heart failure, cardiac conduction abnormalities, Cerebrovascular disease, depressed AV node conduction. Side effects – Edema, headaches, flushing, sinus tachycardia, hypotension Dosages :Adult: 5mg/hr IV/IO Pedi: 0.5 – 5 mcg/kg/min