Updates on BTK Inhibitors and Multiple Sclerosis Trials - Part 1

In part two of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the steps to take if you are screening for a psychiatric comorbidity and the results indicate that someone may be positive for depression, anxiety, or another condition.  Show citations:  Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy. Epilepsia. 2022;63(2):316-334. doi:10.1111/epi.17140  Patel AD, Baca C, Franklin G, et al. Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018;91(18):829-836. doi:10.1212/WNL.0000000000006425  

In the August episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost highlight how the AAN's growing representation within the AMA strengthens the voice of neurology.  Stay informed by watching the President's Spotlight video.  

In part two of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the FENhance 1 and 2 trials looking at fenebrutinib in relapsing  MS.  For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting.  Read more about the Fenebrutinib Trial. 

In part one of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the fenebrutinib trial and highlight the key takeaways that healthcare providers should be aware of.   For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting.  Read more about the Fenebrutinib Trial. 

In part one of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the best methods for screening patients with epilepsy in a clinical setting. Show citations:  Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy. Epilepsia. 2022;63(2):316-334. doi:10.1111/epi.17140  Patel AD, Baca C, Franklin G, et al. Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018;91(18):829-836. doi:10.1212/WNL.0000000000006425  

In the second episode of this series, Dr. Dara Albert and Dr. Jon Stone discuss the future of FND and the innovative topics presented at the conference. 

In part two of this series, Dr. Stacey Clardy and Dr. John Ney discuss what neurologists should do differently after reading this article.  Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618  

In the first episode of this series, Dr. Dara Albert and Dr. Jon Stone emphasize the main takeaway from this year's conference that should be taught to residents. 

In the first part of this series, Dr. Stacey Clardy and Dr. John Ney discuss the key clinical messages for all practicing neurologists.   Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618  

In this lab minute, Dr. Stacey Clardy discusses Susac syndrome and Behçet disease.