Essentials: Manage Stress & Build Resilience | Dr. Elissa Epel

Robert Greene is a bestselling author on human nature, individual expression and growth. He explains the sublime and how to access it: in relationships, work, through observation, expression and more. What emerges is a larger conversation about human consciousness perception and ensuring your life is lived and experienced to the fullest. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Robert Greene (00:02:47) The Law of The Sublime (00:07:40) Accessing the Sublime in Everyday Life, Drugs, Stroke (00:13:11) Sponsors: David & Eight Sleep (00:15:43) Attention, Neuro-Sublime, Tools: Self-Remembering, Meditation (00:23:06) Perception of the World, Emotion (00:29:57) Spatial & Temporal Scales, Childhood, Time as a River (00:39:08) Death Sublime, Near-Death Experiences (00:42:52) Sponsor: AG1 (00:44:06) Octopus, Changing Our Time Perception & Animal Species (00:50:13) Attention, Phone & Vulnerable to Influence, Tool: Slowness (00:55:03) Slowness, Getting Outside of Human Social World, Tool: Mountain Climbing (01:01:53) Experiencing the World Beyond Us, Tool: Think Musically (01:07:57) Slowness in Writing, Tool: Handwriting; Cuttlefish, Hand Gestures (01:15:11) Sponsor: LMNT (01:16:31) Childhood, Tool: Uncovering Your Life’s Task (01:23:31) Stroke & Insight; Finding Sublime in Daily Experiences (01:28:55) Flow & Transcendent Experiences, Prodigies (01:35:24) Sponsor: Function (01:37:02) Love Sublime, Vulnerability & Falling in Love (01:42:33) Love, Trust; Opposites as False Enemies, Embracing Masculine & Feminine (01:47:16) Religion, Awareness of Death, Loss of Spirituality (01:56:28) Best & Worst of Being Human (02:02:49) Accessing the Best of Humanity, Tools: Slowness, Creativity & Senses (02:10:42) Next Book, Invisible, Fiction (02:16:26) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, my guest is Dr. Noam Sobel, PhD, a Professor of Neurobiology at the Weizmann Institute of Science and an expert on the human sense of smell. We discuss how the brain processes odors and how smell shapes our lives more than we realize, influencing everything from who we become friends with to how we experience emotions, hormones and aggression. Dr. Sobel also shares his lab’s groundbreaking work on digitizing smell and future technologies that could enable noninvasive disease detection through body odors. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Noam Sobel (00:00:20) Biology of Smell (Olfaction) (00:04:32) Human Smell, Social Interaction, Handshaking (00:08:31) Sponsor: LMNT (00:10:03) Friendship, Body Odor (00:14:04) Human Chemosignals, Smell of Fear & Contagion (00:15:48) Aggression, Chemosignals, Men vs Women, Babies (00:20:38) Sponsor: AG1 (00:21:51) Tears, “Chemical Blanket”, Testosterone (00:25:37) Digitizing Smells (00:28:25) Sponsor: Eight Sleep (00:29:48) Creating Digital Odors; Future Medical Diagnostics (00:33:43) Acknowledgments Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Ross Edgley is a British ultra-endurance athlete and author known for completing extraordinary athletic feats by tapping into diverse sources of motivation and resilience. We discuss the psychological and biological forces that allow people to persevere through extreme challenges. Then we cover how to dynamically update your sense of purpose, emotions, philosophy, and personal narratives to expand your ability to overcome adversity of all kinds. We also discuss the brain circuits and science of fatigue and stress adaptation. Ultimately, a new framework emerges that you can use to access persistent motivation. Read the show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Lingo: https://hellolingo.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Ross Edgley (00:03:19) Childhood, Motivation Sources; Competition, Pain & Purpose (00:11:51) Anterior Midcingulate Cortex, Wheel of Motivation & Tenacity (00:16:05) Honoring Your Commitment, Ultra-Endurance Swimming, Self-Respect (00:17:46) Sponsors: David & Lingo (00:20:02) Fear of Shame, Iceland; Team Events, Injuries & Sea Swims (00:25:50) Spiritual Experiences, Loch Ness, Iceland, Mythology & Motivation (00:31:37) Dorsolateral Prefrontal Cortex, Persistence & Winning, Strategy (00:36:27) Energy Management; Leadership & Team (00:40:56) Addiction, Evaluating Challenges & Purpose, Support & Yukon (00:47:23) Fear & Animals, Great White Sharks, Bears (00:53:09) Sponsor: AG1 (00:54:22) Proving Others Wrong, Anger, Great Britain Swim (00:57:55) Anger at Self; Doing It For the Sake of Others, Son, Father (01:08:58) Next Endeavor, Money, Helping Others (01:15:29) Dark vs Light Energy, Self-Discipline; Yaminawa Tribe (01:22:51) Sponsor: LMNT (01:24:11) Challenge Stakes, Ultra-Endurance Swims; Negative Thoughts (01:33:29) Tongue; Iceland Swim, Berserker, Third-Person Perspective (01:38:28) Pain Tolerance, Stress Inoculation, Deliberate Cold Exposure (01:45:48) Strength Training (01:48:10) Sponsor: Eight Sleep (01:49:38) Process vs Outcomes, Psychological Adaptability (01:55:07) Cyclops & Tunnel Vision, Yukon Swim; Cuttlefish (02:02:02) Caffeine, Nicotine, Alpha GPC, Creatine, Supplement Use (02:11:59) Strength Training & Workouts, Strength Reserve, Endurance (02:20:26) Girlfriend, Worry; Doing What Others Cannot, Gratitude (02:29:13) Absurd Hero, Pleasure in Struggle (02:31:14) Smile, Motivated through Anger; Spirit Animals (02:41:37) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, I explain how to develop a rational supplementation protocol tailored to your specific needs, nutrition and budget. I discuss foundational supplements and single-ingredient supplements for sleep, hormone support and cognitive enhancement and focus, including how to test individual ingredients, choose appropriate dosages and cycle certain compounds. I also explain why behavioral tools and nutrition remain the foundation for mental health, physical health and performance. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Mateina: https://drinkmateina.com/huberman Timestamps (00:00:00) Supplementation (00:00:12) Behavior, Nutrition, Supplements & Prescription Drugs (00:03:16) Supplementation Context & Individual Needs (00:04:44) Foundational Supplements; Tool: Vitamin & Mineral Supplements (00:06:20) Tool: Sleep, Nutrition & Budget Questions; Broad-Spectrum Supplements (00:08:22) Sponsor: Eight Sleep (00:09:45) Sleep Supplements; Tool: Caffeine & Food Timing (00:10:40) Tool: Middle-of-the-Night Waking, Myo-Inositol; Theanine & Vivid Dreams (00:11:43) Tool: Falling Asleep, Magnesium Threonate & Apigenin (00:12:58) Tool: Test Single-Ingredient Supplements (00:15:00) Melatonin (00:15:48) Hormone Support, Behavior & Nutrition (00:17:05) Fadogia Agrestis, Dosage & Cycling (00:19:24) Tongkat Ali & Free Testosterone (00:20:24) Menstrual Cycle & Supplement Effects (00:21:28) Sponsor: AG1 (00:22:41) Cognitive Enhancement & Focus; Stimulants, Caffeine & Alpha-Yohimbine (00:25:08) Neuromodulators, Alpha-GPC & L-Tyrosine (00:26:51) Stimulants vs. Neuromodulators; Tool: Explore Supplements Separately (00:29:10) Sponsor: Mateina (00:30:19) Omega-3 Fatty Acids & EPA (00:32:14) Protein & Food-Based Supplements (00:34:44) Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Jared Diamond, PhD, is a Pulitzer Prize-winning author, physiologist, evolutionary biologist and Professor at UCLA. We discuss the surprising and often chance events that shaped human history and leadership in politics, religion, business and athletics. As one of the most influential public-facing scholars of the last 100 years, Dr. Diamond also shares his advice on how to pursue a career and life that reflects your unique interests and that makes a positive contribution to the world. He also shares the tools he uses to keep his mind and body vigorous. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Rorra: https://rorra.com/huberman Timestamps (00:00:00) Jared Diamond (00:02:51) Leadership, Prophets; Hitler, WWII (00:09:17) Hitler, Leadership, Deception (00:11:45) Unlikely Leader: Harry Truman (00:13:45) Sponsors: Rorra & Eight Sleep (00:16:28) Leaders, Introspection, Charisma; Individuals, History Patterns (00:22:35) Leaders & Addressing Mistakes, Forgiveness (00:25:36) Religious Leaders, Jesus & Leadership, Organizers (00:30:42) Leader Partnerships, Science, Religion (00:35:18) Jim Jones, Effective Cult Leaders; Followers (00:39:53) Sponsor: AG1 (00:41:06) Leaders & Clinging to Power (00:44:29) Learning Languages (00:49:59) Taxonomy, Lists & Names, Studying Birds (00:56:41) Curiosity, New Guinea Birds, Success & Support Across Different Careers (01:04:55) Travel, Intellectual Explorer (01:07:44) Birds, Vision & Sound, Ecology; Bird Song, Monkeys (01:14:50) Sponsor: Function (01:16:27) Academic Leadership; Time & His Remaining Projects (01:25:54) Humanity Risks, Population Bomb (01:30:46) Physical Activity; Sports Leaders (01:38:08) Coaching Philosophy, John Wooden; Business Leaders, Yvon Chouinard (01:44:31) Great Leadership; Advice for Others (01:51:22) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, my guest is Dr. Matthew MacDougall, a neurosurgeon at Neuralink. We discuss how brain-machine interfaces could help people with paralysis control computers using their intended movements, and how robotic surgery enables the placement of tiny electrodes in the brain. We also explore advances in brain tumor surgery, implant safety, how the brain and software learn to work together, and the role of animal research. Dr. MacDougall shares his vision for future applications, including restoring movement, addressing mental health conditions and expanding human cognition and communication. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Rorra: https://rorra.com/huberman Timestamps (00:00:00) Matt MacDougall (00:00:23) Brain Function, Frontal Lobes & Impulse Control (00:02:57) Brain Tumors, Laser Surgery & MRI (00:04:38) Neuralink, Brain Implants & Paralysis (00:07:04) Robotic Surgery & Electrode Placement (00:08:02) Sponsor: BetterHelp (00:10:25) Motor Cortex, Controlling Computers With the Brain (00:12:20) Implant Safety & Brain Augmentation (00:14:07) RFID Hand Implant & Everyday Uses (00:16:25) Sponsor: AG1 (00:18:03) Spinal Cord Stimulation, Reconnecting Brain & Body (00:19:00) Brain-to-Brain Communication & AI (00:21:13) Brain-Machine Interfaces, Learning & Adaptation (00:23:43) Animal Research & Welfare (00:26:47) Pigs & Monkeys, Device Safety & Function (00:28:04) Sponsor: Rorra (00:30:32) Future Applications, Mental Health & Human Cognition (00:33:03) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Scott Kanoski, PhD, is a Professor of Human and Evolutionary Biology and Neurobiology at the University of Southern California. We discuss how different foods impact memory and cognitive function as well as cravings. We also discuss how GLP-1 drugs work to control hunger in the brain and body, the role of the gut microbiome, and the effects of artificial and low calorie sweeteners on hunger and satiety. This episode highlights how nutrition impacts much brain health and learning capacity and how our memory impacts food choices too. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Function: https://functionhealth.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Our Place: https://fromourplace.com/huberman Timestamps (00:00:00) Scott Kanoski (00:02:33) GLP-1, Natural GLP-1 Production; GLP-1 Drugs, Microdosing (00:07:06) GLP-1 Drugs & Benefits (00:10:36) Sponsor: Our Place & Helix Sleep (00:13:24) GLP-1 & Hunger Suppression, Vagus Nerve; Food Noise (00:18:39) Artificial Sweeteners & Appetite, Preclinical Studies (00:26:50) Memory & Meals; Stress; Eating & Individualization, Fasting (00:33:42) Memory Impairments, Western Diet, High Sugar, Processed Food (00:42:33) Sponsor: AG1 (00:43:46) Dementia, Alzheimer’s Disease & Western Diet; Exercise (00:49:40) Vagus Nerve, Hippocampus & Memory, Hormones (00:57:10) Sugar & Fat Consumption, Memory; Engineering Food for Quality (01:04:32) GLP-1s, Nutrient Deficiency, Weight Loss & Other Effects (01:11:33) Sponsor: LMNT (01:12:54) Vagus Nerve & Hippocampus, Eating & Acetylcholine (01:21:05) Hippocampus, Memory & Food; Interoceptive Awareness & Western Diet (01:27:21) Omega-3s; Microbiome & Processed Foods (01:34:00) Microbiome, Antibiotics, C. diff Infection (01:37:23) Sponsor: Function (01:39:01) Foods to Enhance Microbiome; Rising Obesity & Highly Processed Food (01:43:39) Dopamine & Food Choice, Change Food Cravings (01:49:50) Food Addiction, Highly Processed Foods; Political Lobbying (01:56:43) Oxytocin, Reduced Food Consumption, Social Eating (02:00:11) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, my guest is Dr. Elissa Epel, PhD, a Professor of Psychiatry and Behavioral Sciences at the University of California, San Francisco (UCSF). We discuss how acute and chronic stress affect the body and brain, including their links to cellular aging and mitochondrial health. We also explain tools to reduce rumination, reframe stress as a challenge and build resilience, as well as how radical acceptance and a sense of purpose can help us navigate stressors we cannot change. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Timestamps (00:00:00) Elissa Epel (00:00:22) Good & Bad Stress, Stress Responses (00:01:55) Rumination, Body Awareness (00:03:23) Tools: Mindset, Body & Environment (00:04:51) Acute & Chronic Stress, Energy & Recovery (00:07:44) Sponsor: Eight Sleep (00:09:27) Healthy Aging, Purpose & Brain Health (00:10:54) Stress Resilience, Threat vs. Challenge (00:14:40) Tool: Reframe Stress, “Stress Shields” (00:16:54) Sponsor: AG1 (00:18:30) Mitochondrial Health, Caregiving & Daily Mood (00:21:24) Chronic Stress, Tool: Radical Acceptance (00:25:19) Tool: “Drop the Rope”, Uncontrollable Stressors (00:26:48) Uncertainty, Tool: Posture & Slow Breathing (00:29:10) Sponsor: ROKA (00:30:34) Taking Action vs. Letting Go (00:32:55) Journaling, Narrative & Purpose (00:34:15) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Beth Shapiro, PhD, is an evolutionary biologist and Chief Science Officer at Colossal Biosciences. Her work focuses on de-extinction and wildlife conservation efforts. We discuss genetic differences among humans, and how ancient DNA and modern embryology are being used to de-extinct and protect woolly mammoths, dodo birds, and dire wolves, as well as to help conserve endangered species. We also explore the ethical implications of de-extinction and how synthetic biology can help build a more bio diverse and resilient world. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Beth Shapiro (00:02:35) What is a Species?, Taxonomy, Bison (00:09:13) Neanderthals, Denisovans, Homo Sapiens (00:12:38) Sponsors: Joovv & Eight Sleep (00:15:27) Hybrid Ancestry, “Grolar” Bears (00:20:30) Homo Sapiens & Neanderthal Interbreeding, Genes; Denisovans (00:25:53) Neanderthal Genes, Immunity, Red Hair; Eye Color (00:30:17) De-Extinction, Species Selection, Woolly Mammoths (00:38:08) Sponsor: AG1 (00:39:21) Bird De-Extinction, Dodo; Reproduction & Genes (00:47:40) Development Biology, Woolly Mammoth, Elephants (00:54:49) Dire Wolf, Synthetic Biology, Ethics (01:03:26) De-Extinction, Ecology, Conservation, Ethics (01:09:22) Ecosystem Resilience, Thylacine; Preventing Extinction, Quolls (01:15:45) Sponsor: Function (01:17:23) Modeling Ecological Impact, Mosquitoes, Gene Drives; Panthers (01:25:50) Advisory Panels, Synthetic Biology Education (01:29:13) Genetic Selection in Humans, Human-Shaped World (01:38:25) Black-Footed Ferrets, Genetic Rescue (01:47:05) Dire Wolf; Ecological Modeling, New Technology & Public Fear (01:55:09) Artificial Wombs; Current Issues, Conservation & Red Wolf (02:01:26) Science Pioneers; Colossal Public Education (02:04:31) Beth’s Science Origin Story; Dinosaurs (02:13:42) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, I explain how the neurochemicals epinephrine, acetylcholine and dopamine contribute to focus and concentration. I discuss tools for improving attention, including sleep, sound, structured work sessions, nutrition, caffeine and deliberate cold exposure. I also describe a brief daily meditation and visual focus exercises that train your ability to refocus when attention drifts. Additionally, I discuss the potential benefits and limitations of supplements, prescription treatments for ADHD, and why taking time to deliberately defocus supports concentrated work. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Focus & Concentration (00:02:00) Epinephrine, Acetylcholine & Dopamine (00:04:20) Sleep, White Noise & Pink Noise (00:07:35) Sponsor: LMNT (00:09:05) Ultradian Cycles, 90-Minute Work Sessions (00:10:45) Blood Glucose, Fasting & Meal Size (00:13:40) Caffeine, Focus & Sleep (00:15:00) Acute Stress & Concentration (00:16:55) Tool: Deliberate Cold Exposure (00:19:45) Sponsor: AG1 (00:21:00) Tool: 13-Minute Daily Meditation (00:25:10) Tool: Visual Focus Exercises (00:29:45) Sponsor: David (00:31:10) Omega-3 Fatty Acids & Creatine (00:33:00) Alpha-GPC, Acetylcholine & Safety Considerations (00:35:10) L-Tyrosine, Dopamine & Combining Tools (00:37:00) ADHD, Prescription Medications & Neuroplasticity (00:39:55) Deliberate Defocusing & Recovery (00:41:10) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices