mRNA Technologies

In this episode, we kick off a new series highlighting how genetics appears in pop culture, not only as a powerful science but as a compelling storytelling tool. The focus of this episode is the iconic dystopian video game, BioShock, where genetic engineering and bioethical dilemmas drive both gameplay and narrative. Join us as we explore Rapture’s themes on commercializing evolution and the lessons we can take away from it.

Back with monthly episodes! We’re delving into Colossal Biosciences’ bold plan to revive the woolly mammoth. Join us as we discuss the woolly’s history, Colossal’s attempt to reverse climate change, and the steps to bring back the frozen giant. Science, ethics, and the what-ifs of de-extinction – we’re covering it all in this episode!

In this episode, we discuss mRNA technology, specifically the COVID-19 vaccines. We talk about how they work to protect us from infections and how long this protection could last. We end off by covering other mRNA therapies and voicing our thoughts concerning the future and some of the politics surrounding the vaccines.

In this episode of the Gene Panel, we discuss genetically modified organisms (GMOs). We go over some of the ways GMOs are made as well as some brief history regarding their inception. We also address some of the main public concerns and benefits associated with GMOs. Finally, we give our own opinions regarding GMOs and their future directions.

In this episode, Aideen and Julian talk about how antibodies contribute to making humans resilient to foreign pathogens. The episode starts by entertaining the possibility of a microscopic alien invasion to show generally how immunology can play a role in a variety of fields, including space travel. We cover the genetic basis for the diversity and specificity of antibodies responsible for eliminating disease-causing agents. Additionally, we talk about how antibodies can be useful even outside our bodies, such as in a laboratory setting. We close the discussion by touching on the relevance of antibodies as scientists search for new COVID-19 treatments and prevention methods.

In this episode, we invite the entire Gene Panel Podcast team to discuss our university experiences. Unlike other episodes, this one does not involve any genetics and is more of a conversation among fellow peers. We talk about acquiring practical experience, residence life, commuter life, extracurriculars, and more. 

In this episode, Aideen Teeling joins us to explore the 1993 Jurrasic Park film from a genetics perspective. We delve into the logistics of reviving dinosaurs and debate some of the theoretical procedures associated with recreating and monitoring the extinct species. We also address the role science fiction films and similar media have in sparking discussion surrounding scenarios that could become our reality, such as bringing back an extinct species or salvaging an endangered one.

In this episode we explain some of the science and technology behind the identification, characterization, and tracking of the virus responsible for the current pandemic that is COVID-19. We explain some of the safety practices that can aid in preventing the spread of the virus as well as talking about some of the rumors and “fake news” associated with treating the disease that exists on the internet and other media. Additionally, we go through the process of the making and distribution of vaccines. Finally, we incorporate our own opinions and personal experiences to promote conversation on the future of this pandemic.   

In this supplementary episode we sit down with Dr. Alan Davidson, a joint professor of Molecular Genetics and Biochemistry at the University of Toronto. He and his colleagues discovered anti-CRISPR, so we ask him about the discovery process, how the system works, and how it can be used in tandem with CRISPR to enhance gene editing and disease amelioration. Be sure to tune in to this episode to learn about how an evolutionary arms race between bacteriophage and bacteria has helped scientists and aided in the advancement of medicine!

In this episode we discuss CRISPR and the heavily debated topic of gene editing. We explore gene editing techniques used prior to CRISPR, and how CRISPR was discovered. We address “designer babies” (“test-tube” fertilization with a choice of which traits you want your child to have), and the risks and benefits surrounding such a controversial topic. We also elaborate on the reasons behind Nature’s call for a pause on all germline applications of gene editing in a clinical setting. Finally, we consider the idea of CRISPR being used to make superheroes. Be sure to tune in this episode and learn about the exciting (and frightening) possibilities of gene editing, and why it’s on course to bring about a paradigm shift in medicine!