Don’t Wait to Medicate—Evidence for Early Intervention in Hypertension - Frankly Speaking Ep 454

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-457 Overview: Many patients turn to low- and no-calorie sweeteners to help with weight loss and lower diabetes risk, but do these alternatives actually deliver? In this episode, we review common artificial sweeteners and explore evidence on hunger, cardiovascular, diabetes, and dementia risks to understand how sugar substitutes can impact long-term health outcomes in your patients. Episode resource links: fMRI Data: Nat Metab 7, 574–585 (2025). https://doi.org/10.1038/s42255-025-01227-8 Adverse effects: Adv Nutr. 2023 Jul;14(4):710-717. doi: 10.1016/j.advnut.2023.05.010 Dementia Data: Neurology® 2025;105:e214023. doi:10.1212/WNL.0000000000214023 Stevia: Obes Rev. 2025 Jun;26(6):e13902. doi: 10.1111/obr.13902 High Fructose Corn Syrup:  Nutrition Reviews. 2021;79(2):209-226.  doi:10.1093/nutrit/nuaa077 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-454 Overview: Treating hypertension within the first month can significantly improve long-term blood pressure control. This episode reviews new evidence and practical strategies to help you initiate timely therapy, optimize follow-up, and improve outcomes for patients with newly diagnosed, uncontrolled hypertension. Gain actionable insights to close a critical care gap. Episode resource links: Barrett, R. B., Riesser, B., Martin, B., Sachdev, N., Rakotz, M. K., Sutherland, S. E., & Egan, B. M. (2025). Treatment in the First Month After Hypertension Diagnosis Improves Blood Pressure Control. Hypertension (Dallas, Tex. : 1979), 82(6), 1129–1136. https://doi.org/10.1161/HYPERTENSIONAHA.124.23508 For your patients: 10 Ways to Control High Blood Pressure Without Medication  For your patients: Natural Ways to Lower Blood Pressure  Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-453 Overview: Many patients are still hesitant about the shingles vaccine, but the benefits go far beyond preventing a painful rash. Hear how varicella zoster vaccination can also reduce the risks of postherpetic neuralgia, dementia, and cardiovascular events, giving you powerful tools to guide more informed patient decisions. Episode resource links: Dementia: Neurol Sci. 2024 Jan;45(1):27-36.  doi: 10.1007/s10072-023-07038-7 CV: J Infect Dis. 2025 Feb 28:jiaf105. doi: 10.1093/infdis/jiaf105  Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452 Overview: The healthcare landscape is evolving rapidly, and clinicians are navigating conflicting guidance on established, evidence-based recommendations. Recent news suggest acetaminophen use during pregnancy causes autism spectrum disorder (ASD), which is not the consensus of medical experts based on available data. When guidance from various sources conflicts with established research, clinicians face challenges in providing evidence-based care. Join us to review the current evidence on acetaminophen and ASD risk.  Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172   Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802   Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259   Hirota T, King BH.  Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661   Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8   DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451 Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year. Episode resource links: Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064.  Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217.  Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045.  Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-449 Overview: In this episode, we discuss new evidence linking high compliance with the Dietary Approaches to Stop Hypertension (DASH) diet to lower risks of colorectal cancer, reinforcing the DASH diet’s well-established role in managing hypertension while also highlighting its potential to reduce cancer risk. Gain practical insights into translating these findings into actionable nutrition guidance to support your patients’ overall health. Episode resource links: Explain the risk factors for development of colorectal cancers Review the Dietary Approaches to Stop Hypertension (DASH) and discuss the proposed mechanisms for colorectal cancer reduction by following this approach Apply evidence from a meta-analysis to support dietary counseling strategies aimed at cancer prevention in clinical settings Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-448 Overview: Join us to discover how flavan-3-ols, found in tea, cocoa, and select fruits, can support cardiovascular prevention. Learn how to translate emerging evidence on blood pressure and vascular health into practical dietary guidance that empowers your patients and complements standard hypertension care. Episode resource links: European Journal of Preventive Cardiology (2025) 00, 1–13. https://doi.org/10.1093/eurjpc/zwaf173 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-447 Overview: New data show that quitting smoking—even at age 65 or 75—can still add years to life. In this episode, we review the latest evidence on life expectancy gains and equip you with effective, evidence-based tools to support tobacco cessation and motivate patients at any age. Episode resource links: Le,Thuy TT., Mendez, D. , & Warner, K. (2024). The Benefits of Quitting Smoking at Different Ages. American Journal of Preventive Medicine, 67 (5), 684-688. https://doi.org/10.1016/j.amepre.2024.06.020.    What are the treatments for tobacco dependence? National Institute on Drug Abuse https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-treatments-tobacco-dependence Smokefree.gov offers Apps, counseling, texting support, tools and tips for your patient to build your quit plan Selby, P., & Zawertailo, L. (2022). Tobacco Addiction. The New England journal of medicine, 387(4), 345–354. https://doi.org/10.1056/NEJMcp2032393 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-445 Overview: Managing knee osteoarthritis (OA) in patients with obesity can be challenging, especially when standard treatments fall short. In this episode, we discuss emerging evidence on the use of metformin to reduce knee pain in patients without diabetes and explore how this option could expand your approach to OA management. Episode resource links: Pan F, Wang Y, Lim YZ, et al. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2025;333(20):1804-1812.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-442 Overview: Listen in as we review the USPSTF’s recently proposed recommendations for screening women who are at risk for developing osteoporosis. Gain confidence to navigate these changes and engage patients in shared decision-making to ensure timely, evidence-based preventive care. Episode resource links: JAMA. 2025;333(6):498–508. doi:10.1001/jama.2024.27154 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]