DOCSF 2025: Orrick.com - The State of the Deal: The Financial Climate for Orthopedic Innovation

Recorded live at DOCSF 2025 in San Francisco, this session explores how venture capital and investment strategies are evolving in today’s medtech landscape.Moderator Gregg Griner (Orrick) leads the discussion with two physician-investors who are helping shape the future of healthcare technology:Dr. Omair Khan (ARTIS Ventures) shares insights on the current funding environment, what venture firms are prioritizing in orthopedic innovation, and why some AI-driven tools are entering a period of market recalibration.Dr. Andrew Parambath (Pear VC) brings a clinical lens to the conversation, offering practical guidance on selecting pilot partners, mapping out reimbursement pathways early, and designing companies that can withstand market turbulence.Together, the panel offers a clear and realistic view of what it takes to build and fund successful orthopedic ventures in 2025.This session is perfect for anyone working at the intersection of technology, care delivery, and investment.

In this episode, we bring you a conference favorite, DOCSF Science, where cutting-edge research meets real-world relevance. Moderated by Dr. Fabrizio Billi (UCLA), with insights from Dr. Emel Demircan (CSU Long Beach) and Dr. Stefano Bini (UCSF), this session explores the most impactful AI and robotics research papers shaping healthcare in 2025.The panel unpacks four standout studies, including retrieval-augmented generation (RAG) models trained on peer-reviewed medical literature, multimodal foundational models that integrate text, images, and sensor data, and the latest in digital twins for personalized care. You’ll also hear about advances in cognitive robotics that respond to real-time surgeon behavior in the operating room.Whether you're a clinician, technologist, or curious innovator, this episode will challenge how you think about intelligence, data, and the future of surgery. It’s a clear, thoughtful look at how today’s research is already transforming tomorrow’s care.

Recorded live at DOCSF 2025 in San Francisco, this session brings together thought leaders who are challenging what’s possible in digital health.Moderator Unity Stoakes (StartUp Health) guides the conversation, opening the floor to:Dr. Daniel Kraft (NextMed Health & Digital.Health) shares a rapid-fire overview of breakthrough technologies shaping healthcare, from generative agents and digital twins to programmable biology. He invites clinicians to rethink what's possible as care becomes increasingly personalized and proactive.Dr. Fabrizio Billi (UCLA) explores contextual intelligence, spatial computing, and semantic AI. He explains how these technologies can create more adaptive healthcare systems that understand not just data but the meaning behind it.Brandon Barbello (Archetype AI), who introduces the concept of physical AI. These foundation models are trained on sensor data to recognize patterns in human movement, detect early signs of disease, and support real-time interventions.Dr. Douglas Unis (Monogram Orthopaedics & Mount Sinai) outlines the future of autonomous surgical robotics and how it could reshape surgical workflows and orthopedic practice.This session offers a thoughtful look at how emerging technologies are bringing science fiction closer to clinical reality.

We’re kicking off our DOCSF 2025 conference coverage, recorded live in San Francisco on Friday, October 3rd, with an energizing opening session. The day begins with welcome remarks from Dr. Stefano Bini, founder of DOCSF, and Dr. Ben Ma of UCSF, setting the stage for a weekend of transformative insights in digital orthopedics.Following the kickoff, Dr. Sara Edwards (UCSF) leads a compelling conversation exploring how AI is reshaping every layer of healthcare, from the operating room to the insurance claim.You’ll hear from:Dr. Charlie DeCook shares how radical time transparency and AI scheduling assistants are streamlining outpatient surgical workflows.Dr. Archana Dubey, founding partner of Arches Accelerator, explains how insurers are leveraging AI for faster authorizations, real-time care decisions, and more personalized healthcare delivery.Pradeep Javangula (Everest VC) introduces autonomous AI agents designed to act as collaborative teammates across surgical planning, logistics, and revenue cycle operations.This session sets the tone for what DOCSF is all about. Bold ideas, practical solutions, and the future of digital health in action. Tune in to hear how AI is evolving from a buzzword to a backbone in healthcare.

In this special episode, we sit down with Gabe Jones, co-founder and CEO of Proprio, a company pioneering the next generation of surgical visualization. Gabe shares how Proprio is merging computer vision, depth sensing, and real-time 3D imaging to give surgeons an entirely new way to visualize the operative field, without relying on intraoperative CT or traditional navigation systems.He reflects on the multidisciplinary roots of the company, which were born from a neurosurgeon’s desire to “see around corners,” and how his own background in law, engineering, and philanthropy helped shape Proprio’s mission. We also explore what this kind of technology means for surgical precision, workflow efficiency, and the evolving relationship between human skill and machine intelligence in the OR.If you're looking for a glimpse into the future of surgical intelligence, you shouldn't miss this conversation.

In this episode of DOCSF 2025 Previews, we sit with Sam de Brouwer, co-founder and CEO of XY.ai Labs, an agent-based AI company rethinking how healthcare gets done behind the scenes. With decades of experience in digital health and AI, Sam walks us through the shift from data analytics to truly intelligent, autonomous agents and why that matters for healthcare.She shares how XY.ai is building browser-based AI agents to streamline back-office operations like claims, scheduling, and revenue cycle management, without requiring deep tech stack integrations. From automation to augmentation to prediction, Sam breaks down what AI agents can really do, how they orchestrate across workflows, and why now is the time to rethink what’s possible.It’s a powerful preview of what she’ll showcase live at DOCSF 2025. Don’t miss the chance to learn how agentic AI is reshaping the future of healthcare from the ground up.

In this episode of DOCSF 2025 Previews, we’re joined by Dr. Scott Sigman, orthopedic surgeon, host of The Ortho Show, and longtime advocate for innovation in sports medicine. Dr. Sigman previews the highly anticipated Sports Medicine and Technology session he’ll be co-leading at DOCSF 2025, a dynamic, open-format panel with some of the field’s top thought leaders.He shares what excites him most about the tools available right now, from virtual reality surgical training with PrecisionOS to the growing impact of AI scribes and ambient documentation tools that help reduce burnout and bring humanity back to the exam room. Dr. Sigman also reflects on why orthopedic surgeons are often slow to adopt new tech and why that mindset is shifting fast.If you’re curious about the practical side of innovation in orthopedics, this episode offers a motivating look at what’s possible when we lean into change.

In our last episode of DOCSF Global Innovators, we stopped in Stockholm to meet Anna-Karin Edstedt Bonamy, a pediatrician turned CEO of Doctrin, one of Europe’s leading digital health platforms.She shares how her clinical frustrations became fuel for a platform that’s transforming healthcare encounters across Sweden and beyond.From reducing friction in digital-first workflows to scaling meaningful conversations between patients and providers, Anna-Karin walks us through Doctrin’s journey to make every care interaction count.Tune in as we explore what happens when medical insight meets mission-driven tech, and why Sweden’s healthcare future might just be a few thoughtful questions away.

In this episode of DOCSF Global Innovators, we travel to Sweden to meet Daniel Forslund, a longtime public servant and one of the driving forces behind the country’s digital health transformation. From his early days at the Ministry of Health to redesigning innovation incentives in the Stockholm region, Daniel has rolled up his sleeves and made things happen across government, policy, and healthcare reform.We explore how Sweden’s decentralized system is reimagining infrastructure, why public-private trust is key to progress, and what it really takes to turn pilot projects into lasting change. It’s a journey filled with insight, idealism, and a few hard-earned lessons for anyone navigating innovation in complex systems.Pack your curiosity and join us in Gothenburg for a front-row seat to Sweden’s digital evolution.

In this episode of DOCSF 2025 Previews, we catch up with Dr. Nick Colyvas, orthopedic surgeon, UCSF professor, and longtime advisor to health tech startups. Drawing from decades of experience at the intersection of surgery and innovation, Dr. Colyvas shares why it's time for robotics to step into the sports medicine arena.He highlights key areas where robotics, navigation, and digital scribes are already making an impact, and explains why the most successful startups are the ones that solve real problems, build viable business models, and persevere through the long road to adoption. Dr. Colyvas also previews his breakout session at DOCSF 2025, where he’ll lead a conversation on the future of soft tissue robotics and surgical innovation. If you're ready to reimagine what’s possible in sports medicine, this episode is a must-listen.