Deconstructing Conventional podcast

Dr. Patrick Coles: Toxin Sequestration Theory. What is the Body Doing When You're Unwell?

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The fastest way to get trapped in fear is to start with the wrong premise. So we start somewhere else: what if the body is brilliant, strategic, and always trying to protect you, even when the symptoms look scary? I’m joined by Dr. Patrick Coles, a PhD chemical engineer (Berkeley) with a master’s in biochemistry (Cambridge) and co-author of 170+ research papers, to compare notes on how toxicity-based thinking can reorganize the entire “disease” conversation.

We get into Dr. Coles’ toxin sequestration theory of cancer and why growths like cysts, nodules, stones, and tumors may function as containment strategies rather than random breakdowns. We talk about oxidative stress, reactive oxygen species, and how excess estrogen can act like a toxin when liver detox pathways are impaired, including why hormonal interventions can create unintended downstream problems. If you’ve been searching for terrain theory, root-cause healing, and a clearer model of chronic illness, this section alone will give you a new lens.

Then we challenge germ theory through a practical frame: colds and flu as clearance events. When you treat the immune system like a war machine, it’s easy to see fever, mucus, cough, and inflammation as enemies to suppress. When you treat it like a cleanup crew, those same symptoms can look like intelligent public works. We also dig into what pharmaceuticals are designed to do (accelerate, suppress, or replace) and why “side effects” are actually direct effects that the sales pitch conveniently renames.

If this conversation helps you connect new dots, subscribe, share it with a friend who needs a calmer framework, and leave a review with the biggest premise you’ve changed your mind about.

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