What's Really Important About the Vasa Vasorum | Episode 49

Send us Fan MailHealthcare systems use cult tactics on doctors to forge a disenfranchised workforce, deprived of autonomy and independent thinking. I share my own experience of burnout and reflections on the real cause of burnout in medicine. Contact me for information on my physician burnout recovery program: www.vyvyanelohmd.com

Send us Fan MailMost people with anemia or iron overload don’t think about their immune system but iron levels are very closely linked to inflammation in your body. Learn the details on the regulation of iron stores in the body and the importance of macrophages in iron cycling. Find out how iron impacts insulin sensitivity and metabolic health and what happens when iron is deposited in your brain. liver and other organs.Note: There is a sound glitch at 32:36 and I was saying "spinach is rich in oxalic acid". This interferes with iron absorption.

Send us Fan MailFuzzy science” abounds in the world, and even luminaries fall into its trap sometimes. This review clarifies the mis-explanations of important concepts in lipid science that were discussed in Peter Attia’s podcast. The interview with Dr. Thomas Dayspring resulted in a 7 hour series that promised a deep dive into cholesterol and lipoproteins. Lipid science is a complex and ever-evolving field. Understanding some of the basic tenets of the field helps us traverse more complicated topics. The intention of this review is to help clarify the important points Dr. Dayspring made and to open up the scope of the discussion by examining less considered aspects of cholesterol, lipoproteins and their functions. The deep dive into the topic by Drs. Attia and Dayspring was indeed much needed and appreciated and this review acts merely as supplementary commentary or footnotes to the discussion. Since Attia and Dayspring devoted an impressive 7 hours to their discussion, the 2 hour length in this episode respects the time and effort that went into their series by attending to their points in detail. Let me know your thoughts in the comments. What questions do you have from Dr. Dayspring’s interview?Time stamps: 00:00 Intro 05:11 Criteria for review 06:53 Aligning with their intention 09:29 Feynman's scientific principles 11:28 Phospholipids 18:46 Lipid Rafts 30:54 TD: "All cells make cholesterol." 45:28 The Rare Exceptions 50:45 Lipoproteins & cholesterol in artery walls 1:05:59 Pools of Cholesterol 1:09:50 Lipoprotein density1:12:23 How apoproteins are bound 1:15:04 Statins & liver selectivity 1:21:05 Cholesterol functions & metabolism 1:31:02 HDL 1:34:11 RBC membrane cholesterol 1:36:59 Lipoprotein lineages 1:40:48 ApoE 1:50:40 Cholesterol's function in lipoproteins 1:59:55 Unregulated apoB 2:02:23 Conclusion  My practice: https://vyvyanelohmd.com/work-with-me/

Send us Fan Mail Why Tuberculosis & Atherosclerosis are Siblings!You can learn a lot about someone if you know their family members. That's why we're looking at Tuberculosis in this episode. 1.8 billion of the world's population has been infected by TB. Most of them have latent infection. 10.6 million had active infection in 2021. This common infectious disease has many similarities to atherosclerosis and we could learn a lot about plaque formation by looking at TB.#tuberculosis #tb #atherosclerosis #ldl #cholesterol #metabolichealthTo improve your metabolic health: Tulaversity.comFor health coaches and healthcare professionals: https://www.tulaversity.com/certificationContact/Livestream events: vyvyanelohmd.com

Send us Fan MailWe'll discuss the general process of vascular calcification and some common risk factors for this. How do smooth muscle cells in the blood vessel wall contribute to the process? And what about macrophages? How do statins affect calcification? What about CAC-scores? What would happen if you have a low score and started taking a statin? Which calcified plaques are at highest risk for rupture? Find out in this episode of vlmd rounds.#atherosclerosis #ldl #cholesterol #calciumscoreCourses for Health coaches & Metabolic Practitioners: https://www.tulaversity.com/certificationImprove your metabolic health: www.tulaversity.comLivestream event dates: https://vyvyanelohmd.com/events/

Send us Fan MailLearn about the role of macrophages in atherosclerosis. Where do they really come from? How do they contribute to the plaque? How are they driving the immune reaction? What's the relation between macrophages and T cells? We'll also look at vascular inflammation in the form of autoimmune vasculitis and note the similarities with atherosclerosis.#LDL #atherosclerosis #choelsterol #plaque #heartdisease #vasculitis #macrophagesMy website: vyvyanelohmd.comCheck out the livestream datesWork with me to improve your metabolic health (Metabolic Foundations Program): www.tulaversitycampus.comif you are a health coach or clinician and want to acquire a solid foundation in metabolic health based on the most current science: www.tulaversitycampus.com

Send us Fan MailContinuing on my discussion from episode 48, I lay out the real significance of the Vasa Vasorum. What is it about the vasa vasorum that plays into Atherosclerosis as an autoimmune disease? What's the real difference between the vasa vasorum of veins vs arteries?My website: vyvyanelohmd.comWork with me on your metabolic health: tulaversity.com

Send us Fan MailI've been asked so many times about which end of the blood vessel allows entry of LDL particles that I've decided to address the question in this episode. One of the reasons there is so much confusion around discussion of the vasa vasorum is that we only focus on 1 tiny aspect of it and not the whole picture. All that missing information leads to confusion, "fuzzy talk" about the vasa vasorum and the pathogenesis of atherosclerosis. I've decided to do 2 episodes on the topic and in this 1st part, we'll just look at the full description of the vasa vasorum--its structure and organization. We'll also look at what is happening at the luminal side to clarify the 'back door' vs. 'front door' issue. And then I'll reveal the true significance of the vasa vasorum in part 2. #vasavasorum #atherosclerosis #cholesterol #ldl #heartdisease Online Metabolic Foundations Program: www.tulaversity.com.My website: vyvyanelohmd.com

Send us Fan MailThe Clot Thickens in Atherosclerosis--but How?This episode is based on a request by a listener to address Dr. Malcolm Kendrick's hypothesis on the clot as the underlying initiator of atherosclerosis which he proposed in his book, The Clot Thickens. Based on his observations, Dr. Kendrick talks about atherosclerosis as a blood disorder from increased clotting due to damage to the blood vessel lining. My points in this episode clarify the immune science of atherosclerosis and blood clotting, and delve into the significance and role of platelets in the disease process. Check out livestream events: vyvyanelohmd.com/events/To work with me and join my coaching program: tulaversity.com

Send us Fan MailCholesterol is often considered the troublemaker in atherosclerosis. The medical world vilifies it and with some medications, aims to drive it to the brink of extinction in your body! Although not the inciting event in atherosclerosis, it does have an important role in the disease process and that's the main topic in this episode. I'll reveal "secrets" or rarely discussed aspects of cholesterol metabolism and how that may contribute to atherosclerosis. As usual, all is not quite what it seems in  the marvelous complexity of the human body.Let me know what you think in the comments. Check out my live Q&A show: https://vyvyanelohmd.com/events/To work with me, go to: https://tulaversity.com