#618 The Glycocalyx Connection: Healing Leaky Gut, Leaky Brain & Cognitive Decline with Martha Carlin

What if the most powerful "nutrient" for healing wasn't a pill—but oxygen under pressure? In this solo Root Cause Deep Dive, Coach Debbie Potts explains how Hyperbaric Oxygen Therapy (HBOT) works, what happens inside the chamber, and how to know if your body is truly ready to receive its full benefits. You'll learn how to prepare, pressurize, and repair using the Future You™ HBOT Readiness & Stacking Checklist—inspired by Dr. Scott Sherr's integrative HBOT protocols and The WHOLESTIC Method™ foundations. Inside the episode: 💨 What HBOT is and how 100 % oxygen + pressure drive 1,200 % more oxygen into tissues 🧠 The cellular science—how HBOT restores mitochondria, detox capacity, and brain function 🩸 Readiness checklist: drainage • lymph • bile • minerals • sleep • parasympathetic tone 🌬️ Stacking tools for faster results: breathwork, red-light, sauna, cold therapy, N1O1 lozenges 🦠 Why HBOT supports recovery from CIRS, mold toxicity, chronic fatigue, injuries, and aging ⚙️ Maintenance rhythm & long-term oxygen optimization for performance and longevity Whether you're rebuilding from burnout, optimizing recovery, or preparing for your first HBOT session, this episode shows you how to oxygenate your cells—and your calm—so you can become your strongest, sharpest, most resilient Future You. 🔗 Connect with Dr. Scott Sherr 🌐 https://integrativehbot.com 💊 https://troscriptions.com 📸 @drscottsherr 🔗 Connect with Coach Debbie Potts 🌐 https://www.debbiepotts.net 🎧 YouTube – @CoachDebbiePotts 📸 Instagram – @debbiepottscoach

Feeling wired, anxious, or chronically "on"? You might not be stuck — your nervous system might just need oxygen and safety. In this powerful deep dive, Coach Debbie Potts sits down with Dr. Scott Sherr, a global leader in Integrative Hyperbaric Oxygen Therapy (HBOT), to explore how oxygen + pressure + neurotransmitters can reset your mitochondria, vagus nerve, and mind from the inside out. You'll learn: 💨 How HBOT restores mitochondrial energy, oxygen signaling, and cellular repair 🧠 How GABA and the vagus nerve form your "calm circuit" for stress resilience 🌬️ Why GABA supplements don't work — and how Tro Calm and Tro ZZZ from Troscriptions help your brain create real calm 💧 How to prepare your body for HBOT with detox, drainage, and parasympathetic balance 🌿 Simple ways to strengthen vagal tone — through breathwork, cold therapy, grounding, and nutrition If you've ever wondered how to oxygenate your calm, boost parasympathetic tone, and move from defense to repair, this episode is your roadmap to building a stronger, sharper, more resilient Future You. 🔗 Connect with Dr. Scott Sherr: 🌐 Website: https://integrativehbot.com 💊 Troscriptions: https://troscriptions.com 📸 Instagram: @drscottsherr 🔗 Connect with Coach Debbie Potts: 🌐 Website: https://www.debbiepotts.net 🎧 YouTube: @CoachDebbiePotts 📸 Instagram: @debbiepottscoach

5If you've ever wondered why your CoQ10, NAD, or PQQ stack isn't giving you more energy — this episode will change the way you think about fatigue forever. Your mitochondria aren't just little powerhouses. They're safety sensors — constantly asking one question: "Am I safe enough to make energy right now?" In this solo deep-dive, Coach Debbie Potts unpacks the cutting-edge science of the Cell Danger Response (CDR) — based on Dr. Robert Naviaux's research — and why forcing energy production before your cells feel safe can actually make things worse. You'll learn: 🔬 Why your mitochondria slow energy output on purpose — and how that's a protective response, not a failure. ⚙️ Why supplements like CoQ10, NAD, or PQQ often backfire when used too early. 💡 The six "safety signals" from Ari Whitten's Energy Blueprint that naturally restart energy production. 🧠 How chronic stress, the vagus nerve, and hormones all tie into the same mitochondrial story. 🧘 The three-phase strategy Debbie uses to rebuild energy — from drainage and nervous system repair to targeted mitochondrial support. 📊 How to measure true recovery with PNOĒ Metabolic Testing, HRV, and functional labs. This episode bridges the gap between stress physiology, cellular metabolism, and real-world recovery — showing you why you must calm the system before you can fuel it. If you're tired of chasing energy with supplements that don't work, this is your roadmap back to cellular safety, optimal metabolism, and your Future You. 💻 Learn more or schedule your own PNOĒ Metabolic Test and Future You Reset at www.DebbiePotts.net 📲 Follow @coachdebbiepotts on Instagram for daily WHOLESTIC Method™ tips 🩵 Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.

What if your histamine reactions, skin rashes, and perfume sensitivities aren't allergies at all — but signs of bile backup? In this deep-dive episode of The Coach Debbie Potts Show, Debbie unpacks the powerful yet overlooked connection between choline, bile flow, and histamine balance — and how restoring this triad can transform your energy, digestion, and hormone harmony. 💡 The One-Line Bottom Line: Low choline → low phosphatidylcholine → sticky bile → toxin & estrogen congestion → fatigue, PMS, and chemical sensitivity. Restore choline → restore bile → restore flow → restore YOU. 🧬 What You'll Learn: How your liver turns cholesterol into bile acids — your body's natural "soap." Why phosphatidylcholine (PC) from choline keeps bile fluid and prevents fatty liver. How bile stagnation leads to detox traffic jams, histamine overload, and hormone recirculation. The key roles of taurine, glycine, folate, and B12 in bile and methylation support. Why sluggish bile = dysbiosis + histamine-producing microbes + inflammation. Step-by-step strategy to restore drainage, open detox pathways, and calm sensitivities. 🔁 Fast "Symptom-to-Step" Cheatsheet: Greasy stools or nausea after fat → support PC + bile flow PMS or breast tenderness → bile + methylation nutrients Brain fog after meals → vagus priming + PC Elevated liver enzymes → PC + TUDCA + taurine/glycine Perfume or wine sensitivity → bile stagnation + microbiome hygiene ✨ Key Analogy: If your body's plumbing is clogged, spraying air freshener won't fix it. You don't fix chemical sensitivity by masking the smell — you fix it by unclogging the drain. 🧭 The Takeaway: Chemical sensitivity and histamine intolerance aren't random. They're your body's way of saying: "Drain me before you detox me." 🎙️ Tune in to learn how to: ✔️ Support bile flow naturally ✔️ Calm histamine reactions ✔️ Rebuild your microbiome ✔️ And reclaim your energy, mood, and metabolism 🌐 Learn more at: www.debbiepotts.net #FutureYou #LiverHealth #BileFlow #MetabolicHealth #FunctionalMedicine #Detox #HistamineIntolerance #CoachDebbiePotts ⚠️ Disclaimer: Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.

The Glycocalyx Connection: Healing Leaky Gut, Leaky Brain & Cognitive Decline with Martha Carlin What if the secret to your gut, brain, and vascular health lies in a microscopic sugar-protein layer called the glycocalyx? In this episode of The Coach Debbie Potts Show, I sit down with Martha Carlin, founder of BiotiQuest and The BioCollective, to explore how the glycocalyx, the gut microbiome, and the blood–brain barrier work together to protect our energy, metabolism, and cognitive health — and what happens when they break down. Martha shares her inspiring story of turning her husband's Parkinson's diagnosis into a scientific mission, leading to the creation of Sugar Shift — a probiotic culture designed to rebalance sugar metabolism in the gut. We unpack the science of how this unique formulation helps convert glucose into beneficial metabolites like mannitol, supporting both metabolic and neurological resilience. Together, we discuss: 🧠 What the glycocalyx is — and why it's essential for vascular, gut, and brain health 💥 How inflammation, oxidative stress, and high blood sugar erode your cellular barriers 🦠 The role of gut dysbiosis and endotoxins (LPS) in triggering leaky gut and leaky brain ❤️ How endothelial damage drives fatigue, brain fog, and cognitive decline 🥦 Root Cause solutions to rebuild and protect your glycocalyx, gut lining, and blood–brain barrier 🌿 Nutritional therapy and lifestyle strategies to lower inflammation and boost nitric oxide 🧫 How BiotiQuest Sugar Shift helps redirect sugar metabolism and improve mitochondrial health If you've ever wondered how your gut health connects to your brain clarity, focus, and longevity — this episode will connect the dots between your microbiome, metabolism, and mind. 🎧 Listen & Learn: The science of the glycocalyx and why it's your body's "Teflon coating" How "leaky gut" and "leaky brain" are two sides of the same barrier problem Why protecting your endothelial and gut barriers is key to preventing neurodegeneration The power of targeted probiotics like BiotiQuest Sugar Shift for metabolic repair 🧬 Connect with Martha Carlin & BiotiQuest: 👉 https://www.biotiquest.com Use code COACHDEBBIEPOTTS for savings on Sugar Shift and other microbiome solutions. 🌿 Connect with Coach Debbie Potts: Website: www.debbiepotts.net YouTube: @coachdebbiepotts Instagram: @coachdebbiepotts Podcast: The Coach Debbie Potts Show – available on Apple, Spotify & all major platforms

 Detox isn't a juice cleanse — it's a biochemical process your liver runs 24/7. In this deep-dive episode, Coach Debbie Potts unpacks how choline, bile, and cholesterol form the ultimate metabolic trio that determines your fat-burning, hormone balance, and brain health. Learn how sluggish bile flow, low choline intake, or poor drainage can stall detoxification, drive estrogen dominance, and create that "toxic fatigue" so many midlife women experience. You'll discover: 💥 The 3 Phases of Liver Detox — and what nutrients each requires 🥚 Why choline is the missing link in detox, methylation, and brain health 💧 How bile flow impacts hormones, digestion, and fat metabolism 🩸 Why "high cholesterol" isn't the enemy — but a signal to look deeper ⚗️ The truth about TMAO and why you shouldn't fear eggs or choline 🌿 How to restore metabolic flow with real food, movement, and targeted nutrients When you optimize choline and bile, you ignite your mitochondria, clear toxins efficiently, and unlock your body's natural rhythm of repair. ✨ Learn how to test, not guess, using PNOĒ Metabolic Testing and your FutureYou Functional Review at www.DebbiePotts.net #FutureYou #WHOLESTICMethod #CoachDebbiePotts #LiverDetox #BileFlow #Choline #HormoneBalance #FunctionalHealth #MetabolicTesting #PNOE #Mitochondria #FatMetabolism #Longevity  

Setting the Stage — The North-to-South Root Cause Map: How Inflammation Really Starts "Inflammation isn't random — it's routed." In this first Root Cause Deep Dive episode, Coach Debbie Potts reveals how inflammation follows a predictable north-to-south pathway—from your brain all the way down to your gut barrier. If you've ever felt bloated, foggy, or fatigued and been told it's "just inflammation," this episode explains why—and where it truly begins. You'll learn how stress, low stomach acid, sluggish bile, and a weak gut lining quietly sabotage your metabolism and immunity… and how to fix it step by step. Coach Debbie walks you through how your vagus nerve, stomach acid, bile, enzymes, and glycocalyx work together to keep digestion smooth, detox flowing, and inflammation calm. 🧠 In This Episode, You'll Learn: How the vagus nerve sets the "traffic light" for digestion. Why low stomach acid and enzyme output fuel dysbiosis and fatigue. The hidden role of bile as an antimicrobial, hormone balancer, and gut anti-inflammatory. How the glycocalyx acts as your gut's velvet rope—deciding what gets in and what stays out. How to use real-world "clues" like bloating, stool changes, or post-meal fatigue to find where your system is breaking down. ⏱️ Timestamps 00:00 – Welcome + The Root Cause Map Explained 03:15 – How Stress Turns Off Digestion 06:30 – Stomach Acid: Your First Firewall 10:10 – Bile Flow & Detox Connection 14:20 – Enzymes, Fermentation & Endotoxins 18:00 – The Glycocalyx: Your Forgotten Shield 22:40 – Simple Self-Audit: Where's Your Breakdown? 25:30 – Key Takeaway & The Future You Framework 💬 Key Analogy "Your digestion is like a highway running north to south. The brain is the traffic light, the stomach is the toll gate, bile is the car wash, and the glycocalyx is the velvet carpet at the end. When one signal fails, traffic backs up—and that's what drives inflammation." 🧩 Takeaway Inflammation doesn't happen to you — it happens through you. By restoring the flow from brain to bile to barrier, you can quiet inflammation at its source and build a stronger, sharper, more resilient Future You. 🔗 Learn More Visit www.debbiepotts.net for more Root Cause Deep Dive episodes, blogs, and upcoming FutureYou Health Optimizer Events. Subscribe on YouTube or your favorite podcast app, and share this episode with someone who's ready to understand, not just manage, their inflammation. ⚠️ Safety Note Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions. #GutHealth #Inflammation #FunctionalMedicine #BileFlow #VagusNerve #MetabolicHealth #Digestion #RootCauseRevolution #CoachDebbiePotts #TheWholesticMethod #FutureYou #LiverHealth #HormoneBalance #Glycocalyx #Endotoxemia

Are you feeling "off" even though you're doing everything "right"? In this solo deep-dive, Coach Debbie maps the North-to-South flow of health—from brain and vagus nerve to stomach acid, bile, liver, gut, and mitochondria—so you can see how fatigue, belly fat, restless sleep, brain fog, and hormone chaos are often communication problems, not willpower problems. You'll learn how to restore safety signals, open drainage, support bile and choline, and retrain mitochondria from defense to performance. We connect the dots with real testing—PNOĒ RMR/AMR, GI-MAP, DUTCH, Total Tox, MRT, genetics, and Nutritional Therapy Analysis—so you can stop guessing and start rebuilding your Future You™. In this episode, you'll learn: The North-to-South Map: why vagal tone, stomach acid, and bile set the stage for metabolism. Mitochondrial intelligence & the Cell Danger Response (OAT and PNOĒ clues you can measure). Drainage before detox: Phase 1–2–3 in plain English—what to do first. Bile & choline: how to make/keep bile flowing (foods, nutrients, signs of stagnation). Cholesterol & bile: why bile is your main cholesterol exit route. The Brain–Bile–Barrier Loop: how gut/BBB permeability drives neuroinflammation. Muscle as metabolic medicine: training & protein targets that signal repair. Testing, Not Guessing: how your data becomes your roadmap. Ready to see what your metabolism is really doing? Book your PNOĒ Metabolic Test + Functional Health Review: www.DebbiePotts.net Resources mentioned: PNOĒ RMR & AMR testing GI-MAP stool test DUTCH hormone panel Total Tox (metals, environmental, mycotoxins) MRT food sensitivity test Genetics + Nutritional Therapy Assessment Who this is for: high-performers in midlife, peri/menopause, athletes and go-getters who feel overtrained, under-recovered, or stuck despite clean eating and supplements. Follow & connect: www.DebbiePotts.net | @coachdebbiepotts Share this episode with someone who needs a data-driven path from Metabolic Chaos® → Metabolic Harmony. Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.

The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong? In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression. We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression. You'll learn: 🧬 What the Lipid Energy Model reveals about metabolism and cholesterol transport 🩸 Why LDL-C and ApoB aren't always the villains — and when they actually matter 🧠 What "soft" vs. "hard" plaque really means for your risk 🩺 The best ways to measure and track plaque (CAC vs. CCTA vs. AI-based imaging) ⚡ How insulin resistance, inflammation, and oxidative stress drive true cardiovascular risk 🥑 Why many keto and low-carb athletes become "Lean Mass Hyper-Responders" — and what to do about it Whether you're a clinician, health coach, or curious biohacker, this conversation will completely change the way you think about cholesterol, cardiovascular disease, and metabolic health. 🔍 Topics Covered: 00:00 – Intro & Dave Feldman bio 03:00 – The cholesterol paradox in metabolically healthy individuals 08:00 – The Lipid Energy Model explained 12:00 – What is plaque? (Soft vs. hard) 16:00 – How the Keto-CTA study tracked plaque regression 25:00 – The role of LDL, ApoB, and Lp(a) in context 33:00 – Imaging tools: CAC vs. CCTA vs. AI platforms 42:00 – Insulin resistance, inflammation, and endothelial damage 54:00 – Root cause solutions for cardiovascular health 💡 Key Takeaways: Cholesterol is not the enemy — context and inflammation are. The best way to manage heart disease risk is to measure plaque, not just LDL. Metabolic health > cholesterol numbers when it comes to longevity. Functional and nutritional therapy can stabilize or reverse soft plaque. 🔗 Connect & Learn More: 🌐 Website: www.DebbiePotts.net 🎧 Podcast: The Coach Debbie Potts Show 📺 YouTube: @CoachDebbiePotts 🧬 Learn about Root Cause Revolution™: www.rootcausedoc.com 🩺 Explore Own Your Labs: https://ownyourlabs.com 📚 Read more about the Keto-CTA study: https://citizensciencefoundation.org 🧠 Affiliate Links & Partners: 💊 Functional Nutrition Favorites — Fullscript Dispensary 🧬 Seeking Health Supplements — Code COACHDEBBIEPOTTS 🌿 BEAM Minerals — Code COACHDEBBIEPOTTS 💡 Sunlighten Sauna — Mention Coachdebbiepotts for savings #Cholesterol #DaveFeldman #HeartHealth #ApoB #LDL #PlaqueRegression #KetoDiet #MetabolicHealth #FunctionalMedicine #RootCauseRevolution #CoachDebbiePotts

Are you over 40 and feeling like your body's not responding the way it used to—despite doing "everything right"? Fatigue, stubborn weight, restless sleep, and slow recovery aren't signs of failure… they're signs of adaptation. In this powerful deep-dive episode, Coach Debbie Potts unpacks the real root causes behind midlife metabolic slowdown—through the lens of mitochondria, detox pathways, hormones, and nervous system balance. You'll learn how to read your body's feedback, retrain your biology, and build your Future You from the inside out. Drawing on the latest research from Dr. Robert Naviaux, Ari Whitten, and leading functional medicine labs, Debbie guides you step-by-step through: 🧭 The North-to-South Map: How brain, vagus nerve, stomach, bile, and gut alignment control your metabolism. ⚙️ Mitochondrial Intelligence: Why your "powerhouses" switch into protection mode—and how to bring them back online. 💧 Detox & Drainage Foundations: Why "drainage before detox" is non-negotiable for real cellular repair. 🥚 Bile & Choline Connection: The missing link between hormone balance, brain clarity, and fat metabolism. 🧠 The Brain–Bile–Barrier Loop: How gut toxins (LPS) affect mood, motivation, and energy. 🏋️ Muscle as Metabolic Medicine: Why strength training is your longevity drug after 40. 🌿 The WHOLESTIC Method™: 8 Elements for restoring energy, hormones, and cellular coherence. 🔬 Data-Driven Health: How PNOĒ metabolic testing, GI-MAP, DUTCH, and OAT reveal your body's "energy story." 🧩 The Future You Blueprint: A strategic framework for stress recovery, detox, mitochondrial rebuilding, and hormone optimization. This isn't another quick fix—it's a biology reboot. Discover how to measure, map, and master your metabolism so you can thrive, not just survive, through midlife and beyond. 🌐 Schedule your PNOĒ Metabolic Analysis & Functional Health Review in Solana Beach, CA at www.DebbiePotts.net. 🎧 The Coach Debbie Potts Show | 💪 The WHOLESTIC Method™ & Future You Program #FutureYou #TheWHOLESTICMethod #CoachDebbiePotts #MetabolicHealth #PNOE #FunctionalMedicine #Mitochondria #MidlifeHealth #Longevity #BioIndividuality #MetabolicFlexibility