5 Things to Know Before the Opening Bell 1/28/2026

After much Wall Street and Main Street anticipation, President Trump has announced his nominee for Federal Reserve chairman: Kevin Warsh. CNBC’s Steve Liesman discusses the choice, what it means for the markets, especially given Warsh’s history of critiquing the central bank itself. Exxon Mobil posted strong results this quarter, despite oil’s price decline. Exxon CEO Darren Woods discusses the global oil supply and Venezuela’s future. Plus, Maryland Governor Wes Moore discusses the future of the Democratic Party, including his own approach to affordability, wealth redistribution, and taxes.  Governor Wes Moore - 03:44Steve Liesman 20:38Darren Woods 34:33 In this episode:Wes Moore, @GovWesMooreSteve Liesman, @steveliesmanBecky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinKatie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Luke Rosen was working as an actor and writer in New York when his daughter Susannah was diagnosed with KIF1A, an ultra-rare neurodegenerative condition. It's often fatal. At the time they received Susannah's diagnosis, Luke and his wife Sally didn't have much hope. There was no treatment for KIF1A, and there wasn't much work being done on it among researchers. But Luke, one of the most optimistic people you'll ever meet, did what so many parents of children with rare diseases do...he threw himself at the problem. He and Sally started the KIF1A.org Foundation so they could start building research that could go towards finding a treatment for their daughter.  It was the beginning of a long journey for the family. Ultimately, that journey led them to the n-Lorem Foundation, an organization founded by CNBC Cures Advisory Board member Dr. Stan Crooke that offers free ASO treatments to individuals with nano-rare diseases. Thirty years in the making, Antisense oligonucleotide (ASO) technology bridges genomic discovery to personalized medicine one patient at a time. Because of the work done by n-Lorem, Susannah is now receiving treatment for her KIF1A. Luke says the treatments helped for while, though he's now worried the disease is catching up.For more about Susannah's story: visit: https://www.kif1a.org/n-lorem's work is here: https://www.nlorem.org/ Join us in advancing awareness and understanding of rare diseases. Visit CNBC.com/Cures to access clips, resources, or to sign up for our weekly newsletter.  Follow Becky Quick on X: @BeckyQuickPlease share your thoughts or rare disease story in the comments, and join us on The Path. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Meta has reported strong quarterly results, highlighting AI-driven shifts to the company’s business. The SEC and CFTC are hosting a joint conference to underscore collaboration on crypto and the digital assets market structure bill. SEC Chair Paul Atkins and CFTC Chair Mike Selig discuss the dynamic between the crypto and finance industries and making America competitive for crypto business. President Trump has warned Iran that it should make a nuclear deal with the U.S., or face a large-scale American attack. Former senior advisor on energy policy in the Biden administration’s State Department Amos Hochstein discusses the prospect of an attack on Iran over the weekend. Plus, Accuweather’s Bernie Rayno considers the likelihood of another winter storm over the weekend. Paul Atkins & Mike Selig - 8:27Amos Hochstein - 20:15Bernie Rayno - 30:20 In this episode:Paul Atkins, @SECPaulAtkinsMike Selig, @MichaelSeligAmos Hochstein, @amoshochsteinBrian Sullivan, @SullyCNBCBecky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinKatie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

CNBC Leaders Playbook features candid conversations with the world’s top CEOs and business leaders about how they think, decide, and lead, hosted by CNBC Senior Media & Tech Correspondent Julia Boorstin.In this episode, Lowe’s CEO Marvin Ellison and Executive Vice President of Human Resources Janice Dupré discuss bringing new life to the home improvement brand and how they delivered a multibillion-dollar upgrade, from the sales floor to the supply chain. All-new episodes air Wednesdays at 10PM ET/PT on CNBC. Visit CNBC.com/LeadersPlaybook for more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

CNBC Leaders Playbook features candid conversations with the world’s top CEOs and business leaders about how they think, decide, and lead, hosted by CNBC Senior Media & Tech Correspondent Julia Boorstin.In this episode, Airbnb CEO Brian Chesky discusses how he went from an industrial design major to tech founder and CEO of thehome sharing app which forever changed the way we travel, plus the major shift in his approach to leadership. All-new episodes air Wednesdays at 10PM ET/PT on CNBC. Visit CNBC.com/LeadersPlaybook for more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

New York’s new Mayor Zohran Mamdani sits down with Andrew Ross Sorkin for a conversation about taxing the wealthy, preparing for ICE agents in New York, and managing the city’s deficit. Becky Quick sits down with former Citigroup CEO Sandy Weill, now known for his philanthropy. Weill brings University of California Davis Chancellor Gary May and UC Davis Dean of the Veterinary School of Medicine Mark Stetter to discuss the Weill Family Foundation’s latest gift: $120 million for animal health. Plus, CNBC’s Sharon Epperson shares exclusive data from executives on why they have or have not responded to killings of Americans at the hands of ICE after Apple CEO Tim Cook and OpenAI CEO Sam Altman issued statements to employees, addressing ICE activity in Minneapolis.    Sharon Epperson - 07:03 Mayor Zohran Mamdani - 15:17 Sandy Weill, Gary May, & Mark Stetter - 31:42   In this episode: Zohran Mamdani, @NYCMayor Sharon Epperson, @sharon_epperson Becky Quick, @BeckyQuick Andrew Ross Sorkin, @andrewrsorkin Katie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The 5 things to know before the stock market opens today: the Federal Reserve will announce its latest interest rate decision today, Elevance Health stock fell after a Trump administration proposal on Medicare, shares of South Korean chipmaker SK Hynix are moving higher after reporting a record yearlong profit, and shares of both Dutch chipmaker ASML and Texas Instruments are higher, boosting the entire chip sector.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

New York City Mayor Zohran Mamdani faces his first major test as a massive snowstorm hits the city. Partnership for New York City President and CEO Steven Fulop, in his first TV interview since taking the helm, discusses the outlook for business in New York under Mamdani’s leadership. Then, after 60 executives of Minnesota-based companies co-signed a letter calling for calm in Minneapolis, former chairman and CEO of Minnesota-based Medtronic Bill George weighs in the corporate response to the fatal shootings of U.S. citizens at the hands of ICE. George discusses the difficult balance between maintaining a relationship with the Trump administration and prioritizing their business interests. Plus, India and the European Union have reached a trade deal, and Corning landed a $6 billion AI infrastructure contract with Meta. Steven Fulop - 09:29Bill George - 21:43 In this episode:Bill George, @Bill_GeorgeSteven Fulop, @StevenFulopBecky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinCameron Costa, @CameronCostaNY Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

After an ICE officer shot and killed another U.S. citizen in Minneapolis, CEOs of Minnesota-based companies have urged for calm as tensions rise. CNBC’s Eamon Javers reports on the federal, local, and corporate response to the fatal shootings, and CNBC’s Emily Wilkins reports on the Senate standstill over DHS funding that could lead to a partial government shutdown. Author and Tulane professor Walter Isaacson examines the shift in America’s international reputation amid anti-ICE protests around the country. U.S. Transportation Secretary Sean Duffy points to Minnesota Governor Tim Walz and Minneapolis local law enforcement as culpable in the shootings. Plus, as much of America digs out of a massive winter storm, Secretary Duffy expects travel to be back on track by midweek.  Eamon Javers - 2:58Emily Wilkins - 13:19Phil LeBeau - 15:59Walter Isaacson - 24:26Sec. Sean Duffy - 37:08 In this episode:Sean Duffy, @SecDuffyEamon Javers, @eamonjaversEmily Wilkins, @emrwilkinsPhil LeBeau, @LebeaucarnewsBecky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinCameron Costa, @CameronCostaNY Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

After serving 4 months in prison and receiving a pardon from President Trump, Binance founder and former CEO Changpeng “CZ” Zhao sits down with Andrew Ross Sorkin at the World Economic Forum in Davos. In an exclusive and candid interview, CZ reflects on his time in prison and what he would do differently, if he were starting Binance again. Plus, CZ shares his expectations for crypto in the coming year. In this episode:Changpeng Zhao, @cz_binanceAndrew Ross Sorkin, @andrewrsorkinCameron Costa, @CameronCostaNY Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.