Giants Shoulder

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinDalibor Sames is a Columbia University chemist who has spent more than twenty years on a single molecule: ibogaine. His lab built the fluorescent tools that let you watch neurotransmitters move through living brain tissue — and used them to show that ibogaine works nowhere a drug is supposed to work. When they screened it against the 40 to 50 receptors every psychoactive drug hits, the result came back empty. Then he flew to Mexico, took it himself for thirty-six hours, and came back with a new theory of pharmacology.Expect to learn:- The Screen That Came Back Empty: cannabis hits CB1, LSD hits serotonin receptors, ibogaine binds nothing they tested- The Stimulant That Lowers Dopamine: every other stimulant raises it, and ibogaine still doesn't cause parkinsonism- Molecular Wizardry: how one molecule refolds proteins your own genes got wrong- Thirty-Six Hours: his account of the molecule drawing its own atomic structure and teaching him chemistry- Matrix Pharmacology: the theory that ibogaine reads a living system from the insideSPONSORSDownload the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiantsGS EPISODES MENTIONEDDalibor Sames - Meet The Greatest Ibogaine Psychedelic Scientist You've Never Heard Of: https://youtu.be/K9whp_wtCocDeborah Mash - Meet The Ibogaine Psychedelic Scientist Who First Unravelled Its Big Mystery: https://youtu.be/z7eRtXV6ptAGUEST LINKSColumbia Chemistry faculty page: https://www.chem.columbia.edu/content/dalibor-samesSames Lab: https://www.samesgroup.org/professor-dalibor-samesMatrix pharmacology / transporter paper: https://www.biorxiv.org/content/10.1101/2025.03.04.641351Oxa-Iboga paper (Nature Communications, 2024): https://doi.org/10.1038/s41467-024-51856-yGilgamesh Pharmaceuticals: https://www.gilgameshpharmaceutical.com/Beond Ibogaine Clinic (where he took ibogaine): https://beondibogaine.comLISTEN ONYouTube - https://youtu.be/R8zZ3x4FIasApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:43 Twenty Years Chasing One Molecule0:05:36 Why He Finally Took Ibogaine Himself0:07:17 Thirty-Six Hours Of "Chapters"0:09:42 The Molecule Drew Its Own Structure0:17:20 Day Two: The Download Kept Coming0:24:55 Lucid And Tripping At The Same Time0:29:17 300 Trip Reports: The Common Themes0:33:03 It Finds The One Thing You're Hiding0:35:39 Telephone Booths To Your Future Self0:40:25 Noribogaine, The Metabolite Nobody Tracks0:46:30 The Heart Risk That Kills People0:49:21 Now We Break Everyone's Brain0:53:03 The Receptor Screen Came Back Empty0:56:28 The Opioid Paradox1:05:24 Matrix Pharmacology, Explained1:07:28 Ion Channels And The Nicotinic Pore1:17:14 The Transporters: SERT And VMAT21:25:06 The Result That Drove His Students Crazy1:31:04 Molecular Wizardry: Refolding Broken Proteins1:35:53 Don't Call It A Dirty Molecule1:41:21 A Stimulant That Lowers Dopamine1:48:29 A Molecule That Reads The Living Matrix1:49:55 The Ibogaine Genome Project: Billions Needed2:00:34 The Man In Aspen Who Walked Again.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinVinney Tolman is a near-death experiencer, the co-author of The Light After Death and co-founder of the nonprofit Living God's Light. In 2003, aged 25, a supplement twenty times stronger than he realised left him collapsed in a restaurant bathroom. By his account, paramedics declared him dead and zipped him into a body bag, and a rookie medic got his heart beating again 47 minutes later. He says he watched all of it from the ceiling.Expect to learn:- The Body Bag: why a rookie medic broke protocol and unzipped it- Three Heartbeats: what dying felt like, from the loud pop to weightlessness- Hearing Their Thoughts: the medics' minds, and the moment he realised the body was his- The Guide On The Big Screen: the spirit guide he says he recognised in a town-history slideshow six months later- Endogenous DMT: whether the brain's own psychedelic could explain any of itSPONSORSGet Unlimited AI Research Agent Usage with SciSpace (CGIANT for 35% off Advanced or Max plans) - https://scispace.com/?via=crgiantGS EPISODES MENTIONEDRick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscDavid Nichols - Meet The Greatest Living Psychedelic Scientist You've Never Heard Of: https://youtu.be/6umTgXsW1lQAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAGUEST LINKSLiving God's Light: https://livinggodslight.org/The Light After Death (2022): https://thelightafterdeath.com/Living God's Light on YouTube: https://www.youtube.com/@LivingGodsLightInstagram: https://www.instagram.com/vinneytolman/International Association for Near-Death Studies: https://iands.org/LISTEN ONYouTube - https://youtu.be/kmH6LxEZle4Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:38 Who Is Vinney Tolman?0:03:34 The Supplement That Was 20 Times Too Strong0:04:55 Pronounced Dead And Put In A Body Bag0:06:53 The Rookie Who Broke Protocol0:08:14 Watching His Whole Life Up To Age 250:09:35 "No Son, I'm Not God"0:13:14 Earth Is A Grad School0:17:30 What Leaving The Body Actually Felt Like0:20:55 Three Heartbeats, Then Nothing0:24:16 Feeling Sorry For "Whoever The Dead Guy Was"0:25:29 Hearing Every Medic's Thoughts0:26:55 Tracking Down The Rookie Medic0:33:28 The Moment He Realised The Body Was His0:37:36 "We Are Not Our Bodies"0:43:48 Did He Look For A Scientific Explanation?0:52:09 Do All Near-Death Experiences Look The Same?0:54:38 The Being That Asks If You Want To Live0:58:37 His Guide's Name, And A Photo Six Months Later1:04:34 Is It Just DMT?1:10:08 A 12-Hour Meditation And Three Letters: DMT1:12:06 Evan Pushes Back On Endogenous DMT1:19:26 Watching Them Find His Slot In Time1:20:50 Ripping Out His Own Breathing Tube1:27:19 "Don't Believe What You See In This World".....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinAnderson Todd is a cognitive scientist who studies consciousness from the inside. He teaches cognitive science at the University of Toronto, is Assistant Director of its Consciousness and Wisdom Studies Lab, works as a registered psychotherapist, and sits somewhere between Carl Jung and artificial intelligence. Salvia once destroyed his universe. An hour later, he went back in.Expect to learn:- The Salvia Trip: why the beings he met tore the universe apart to teach him respect- Bad Trips Are Good Trips: how salvia's kappa opioid effect may reorganise the mind, and its surprising antidepressant effect- The Dream Herb: the African plant that does nothing awake but supercharges your dreams- The Spider God: the LSD trip at 17 that ended in a lifelong pact- You Are Not One Person: why the entities people meet may be split-off parts of their own mindsSPONSORSCheck out Scispace (JNGIANT20: 20% off the monthly plan or JNGIANT40: 40% off the annual plan) - https://scispace.com/?via=jun1giantshoulderGS EPISODES MENTIONEDDavid Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5oDavid Spiegel - World's Greatest Hypnosis Scientist Makes My Arm Levitate Live On Camera!: https://youtu.be/eCtRBZHIsgQMichael Levin - Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyMJohn Vervaeke - No.1 Biopsychist: Michael Levin's Platonic Minds & Cognition All The Way Down: https://youtu.be/jcMtjjeUV98GUEST LINKSUniversity of Toronto Profile: https://www.uc.utoronto.ca/staff-faculty-profile/anderson-toddYouTube: https://www.youtube.com/c/AndersonToddLISTEN ONYouTube - https://youtu.be/rvPqc7isZ0EApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:05 Somewhere Between Carl Jung and AI0:04:15 Why Cognitive Science Is the Heir to Alchemy0:13:36 The Salvia Trip That Destroyed the Universe0:19:50 "We Destroyed the Universe to Teach You a Lesson"0:22:10 An Hour Later, He Went Back In0:23:26 "You Have Attended Your Own Funeral"0:28:37 Why Bad Trips Can Be Good Trips0:32:26 Salvia's Surprising Antidepressant Effect0:45:48 Turning Into a Japanese Rose Garden0:48:23 Silene Capensis, the Lucid Dream Herb0:53:58 Why Dreams Aren't Random Noise0:59:59 90% of DMT Users Meet Entities1:07:33 "I Have an Arrangement With a Spider"1:13:31 Split Brains and Multiple Selves1:18:55 Hypnotised Into Forgetting How to Read1:19:39 Evan's Arm Rises Under Hypnosis1:24:53 One Session, 30 Years of Smoking Gone1:31:48 Are the Entities Out There, or Inside You?1:38:57 Why Do So Many People Meet Mantises?1:42:35 Why Scientists Hide Their Weirdest Experiences1:49:55 The Third Man: Explorers' Invisible Companion1:52:54 The Giraffe Liver Dream Drug2:00:03 How Michael Levin Broke His Materialism2:02:40 Taking On Dennett: "The Most Primary Data I Have".....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinThomas Hartung is the toxicologist who helped pioneer organoid intelligence: growing human brain tissue in a dish and wiring it up to see whether it can learn. He directs the Johns Hopkins Center for Alternatives to Animal Testing, and before that ran the European Commission's centre for validating alternatives to animal tests. His lab grows half-millimetre brain organoids by the tens of thousands. They can get better at a simple game. By the next day, they've forgotten all of it.Expect to learn:- The Pee Question: yes, you can grow a mini brain from the few cells in your urine- The Missing Cell: why organoids lacked the brain's immune cells, and why memory depends on them- The Overnight Wipe: they improve within a training session, then forget everything by the next day- The Bored Brain: why neurons in a dish are "longing for input"- The Ethics Line: could a cluster of brain tissue ever suffer, and who gets to decide?SPONSORSDownload the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiantsGS EPISODES MENTIONEDBrett Kagan - Meet The Neuroscientist Creating New Forms of Sentient Biological Intelligence: https://youtu.be/TXlJc4tu1F8Karl Friston - Meet The Neuroscientist Who Created The Best Universal Theory Of Brain Function: https://youtu.be/R-IZOFs4qmYMichael Levin - Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyMGUEST LINKSJohns Hopkins Faculty Profile: https://hub.jhu.edu/experts/profiles/thomas-hartung/Center for Alternatives to Animal Testing (CAAT): https://caat.jhsph.edu/Organoid Intelligence (OI): The New Frontier in Biocomputing (Frontiers in Science, 2023): https://www.frontiersin.org/journals/science/articles/10.3389/fsci.2023.1017235/fullFrontiers in Artificial Intelligence (Field Chief Editor): https://www.frontiersin.org/journals/artificial-intelligenceLISTEN ONYouTube - https://youtu.be/4xNxOXNCG-EApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:11 Why Animal Testing Is Outdated Technology0:04:13 What A Brain Organoid Actually Is0:06:51 Can You Grow A Brain From Your Urine?0:10:48 Tens Of Thousands Of Snowflake-Sized Mini Brains0:11:54 The Brain's Missing Immune Cells0:16:23 How Organoid Intelligence Began0:18:21 The Neurons That Learned To Play Pong0:21:50 Punished With White Noise0:24:38 They Learn, Then Forget Everything Overnight0:26:05 The Holy Grail: Long-Term Memory0:29:22 Why Trained Behaviour Isn't Intelligence (Yet)0:32:23 "Yeah, They're Thinking"0:35:08 Testing Drugs On Mini Brains0:37:00 A $15 Million Bet On Alzheimer's0:40:56 A House Fly's Worth Of Human Neurons0:43:43 The Frankenstein Problem0:46:20 "We Could Probably Make A Dragon"0:51:07 "Can I Talk To Them?" No.0:54:24 Animal Testing Is Losing The Public0:57:37 Could A Mini Brain Ever Suffer?0:58:53 "These Organoids Will Never Be Cuddled"1:02:20 Your Brain vs A $600M Supercomputer1:03:58 Ask ChatGPT, Get Eaten By The Tiger1:10:00 What Comes Next For Organoid Intelligence.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinFrantišek Baluška is the cell biologist who helped turn plant intelligence from a fringe idea into a field. At the University of Bonn he co-organised the first Symposium on Plant Neurobiology, and his lab showed that the same anaesthetics that knock humans out stop a Venus flytrap from snapping shut. With Arthur Reber and William Miller he co-wrote The Sentient Cell, which argues that cognition didn't begin with brains, but with the very first cell.Expect to learn:- The Anaesthetised Flytrap: why plants go under with the same drugs that knock us out- The Addicted Ants: how acacia trees hook their bodyguards so they refuse any other food- The Root Brain: Darwin's idea that every root tip acts like a mini brain- The Self-Assembling Animal: separate every cell of a hydra and it rebuilds itself- The Lost Cancer Cell: why tumours may be cells that have lost their map of the bodySPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDMichael Levin - Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyMWilliam B. Miller Jr. - Meet The Scientist Proving Your Cells Are Conscious and Intelligent: https://youtu.be/xrV5oGyyKSIDenis Noble - Denis Noble: Evolution Has Purpose, Cell Consciousness & Why The Last 70 Years of Genetics Is Wrong: https://youtu.be/xqw-DaWVK24Philip Ball - Philip Ball: "Biology Is Infinitely Weirder Than We Thought": https://youtu.be/9SseGx0R0fYGUEST LINKSUniversity of Bonn (IZMB) Group Page: https://www.izmb.uni-bonn.de/en/plant-cell-biology-1/ag-baluskaThe Sentient Cell (2023): https://global.oup.com/academic/product/the-sentient-cell-9780198873211Anaesthetics Stop Plant Organ Movements (Annals of Botany, 2018): https://pmc.ncbi.nlm.nih.gov/articles/PMC6215046/Senomic View of the Cell: Senome versus Genome (2018): https://pmc.ncbi.nlm.nih.gov/articles/PMC6132427/The Third Way of Evolution: https://www.thethirdwayofevolution.com/people/view/frantisek-baluskaLISTEN ONYouTube - https://youtu.be/QbBnYnm4OTgApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:26 From Plant Roots To The Very First Cell0:05:37 Plants vs Humans: Different In Scale, Not Kind0:08:59 How Plants Turn Caterpillars Into Cannibals0:10:08 The Tree That Gets Ants Addicted0:13:26 Blind Biochemistry Or Real Cognition?0:15:22 Do Cells Choose Their Own Mutations?0:19:37 The Senome: The Cell's Missing Layer0:23:55 "What Is Living Can Be Anaesthetised. The Rest Is Dead."0:27:39 Wounded Plants Anaesthetise Themselves0:29:02 How Do You Know A Daffodil Is Knocked Out?0:36:03 The Field Science Tried To Shut Down0:37:25 Darwin's Root-Brain Hypothesis0:38:55 Roots That Swarm Like Birds0:40:51 Underground Plant Wars0:41:31 The Fungal Internet0:47:10 Could AI Let Us Talk To Plants?0:50:00 Cell Sentience vs Human Consciousness0:53:10 Why Your Sense Of Self Is An Illusion0:57:03 The Animal That Rebuilds Itself From Loose Cells1:01:46 Your Membrane Traces Back To The First Cell1:05:52 Heart Transplants And Personality Changes1:10:31 Cancer Cells Have Lost The Map1:15:15 "The Gene Outside The Cell Is Nothing"1:16:47 Will Michael Levin Win A Nobel?.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinJohanne Nedergaard is the cognitive scientist who, with Gary Lupyan, named anendophasia: the absence of an inner voice. An assistant professor at Aarhus University and a 2024 Aarhus University PhD prize winner, she ran the first experiments testing what changes when the voice in your head goes quiet. The answer was far less than anyone expected.Expect to learn:- The Missing Voice: why some people report no inner speech at all, and why nobody noticed- The Rhyme Test: they struggled with word lists and rhymes, until they said the words out loud- Mind Over Muscle: jam someone's inner voice and they push less hard on the bike- Heart Talk: raising your heart rate while lying perfectly still, using only words- The Control Question: why mental health tracks whether you can switch your inner voice off, not whether it's kindSPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDRussell Hurlburt - No. 1 Inner Experience Expert: Inner Monologue, Aphantasia and How Your Mind Lies to You: https://youtu.be/j0gKl-g3DNgAdam Zeman - The Blind Mind’s Eye: How Aphantasia Is Rewriting Consciousness ! Dr Adam Zeman: https://youtu.be/SgA2up6-BokAlex Hutchinson - Alex Hutchinson: The Lie That Unlocked Human Limits, Tricking Perception & Aphantasia!: https://youtu.be/YqqU4ckq8s8GUEST LINKSAarhus University Profile: https://pure.au.dk/portal/en/persons/[email protected] Site: https://johannenedergaard.github.ioBluesky: https://bsky.app/profile/johanneskned.bsky.socialNedergaard & Lupyan (2024), Not Everybody Has an Inner Voice: https://doi.org/10.1177/09567976241243004Nedergaard et al. (2023), Mind Over Body: https://doi.org/10.1016/j.psychsport.2023.102472Wallentin et al. (2025), Heart Talk: https://doi.org/10.1111/psyp.70138LISTEN ONYouTube - https://youtu.be/a81yY0k4x78Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:02 What Is Anendophasia?0:04:19 The Viral Threads That Started It All0:05:57 Four Experiments on People With No Inner Voice0:07:12 Saying the Words Out Loud Closed the Gap0:14:10 Can You Trust Your Own Introspection?0:17:27 Detecting Inner Speech From the Outside0:19:56 How Many People Have No Inner Voice?0:20:54 Where Your Inner Voice Comes From0:23:24 Is It Genetic?0:26:06 Unconscious Inner Speech and the Aphantasia Parallel0:30:58 Deaf People Sign to Themselves Silently0:33:25 What Your Self-Talk Reveals About Your Sport0:35:46 Jam Your Inner Voice and You Push Less Hard0:43:45 Raising Your Heart Rate With Words Alone0:47:12 Positive vs Negative Self-Talk in Sport0:52:55 What Silent Minds Reveal About Thinking0:56:13 Mental Health Is About Control, Not Content1:02:23 Psychedelics and the Inner Voice1:03:51 Can You Train an Inner Voice?1:07:25 They Never Rehearse Conversations.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinDonald Hoffman is the cognitive scientist whose own maths told him reality isn't what it seems. Around 1986, after seven years modelling perception, the equations said we render the world on the fly, and he has been recovering ever since. Now Professor Emeritus at UC Irvine, he has founded the Trace Institute to rebuild physics from conscious observers, starting outside spacetime. Its first collaboration, with Andrew Gallimore, asks whether DMT entities are glimpses beyond the headset.Expect to learn:- The Trace: the 121-year-old maths behind every observer window- Zero For Trillions: why no theory of consciousness explains a single experience- The Nose Test: why seeing your own nose shows how restricted your headset is- The DMT Experiment: passing information through an entity under controlled conditions- Mach 40: what UFOs might look like to someone with the headset's source codeSPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeJoin the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2GS EPISODES MENTIONEDAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAMichael Graziano - Is This Greatest Consciousness Theory You’ve Never Heard Of: https://youtu.be/ZnasmLpY5_8David Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5oKarl Friston - Meet The Neuroscientist Who Created The Best Universal Theory Of Brain Function: https://youtu.be/R-IZOFs4qmYGUEST LINKSTrace Institute Profile: https://traceinstitute.org/people/donald-hoffman/Trace Institute Website: https://www.traceinstitute.org/Trace Institute YouTube: https://www.youtube.com/@TraceInstituteX: https://x.com/donalddhoffmanUC Irvine: https://sites.socsci.uci.edu/~ddhoff/The Case Against Reality (2019): https://wwnorton.com/books/9780393254693Trace × Andrew Gallimore (DMT research): https://traceinstitute.org/collaborations/gallimore/LISTEN ONYouTube - https://youtu.be/dOAo04b6jCQApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:45 The Biggest Unsolved Problem In Science0:05:38 Physicists Say Spacetime Is Doomed0:11:03 Dennett, Graziano And The Illusion Of Consciousness0:14:35 What Is A Trace? Markov Chains Made Simple0:22:23 The Discovery That Founded The Trace Institute0:26:10 Recursive Trace Logic: How Observers Become Agents0:31:27 The CCTV Metaphor For Reality0:37:01 Why There's Always A Nose In Your Vision0:41:08 How Big Is Reality Beyond The Interface?0:43:10 What "Consciousness Is Fundamental" Actually Means0:52:43 Consciousness Science Has Explained Zero Experiences0:58:03 Does Your Consciousness Belong To You?1:01:57 If Consciousness Is One, Why Isn't Telepathy Common?1:08:16 "I Have No Neurons"1:11:13 The Maths That Slapped Him In 19861:20:04 Andrew Gallimore And The DMT Entity Experiment1:26:34 The Swami Who Showed Zero Powers1:32:08 The DMT Mantis And Why Reports Are So Consistent1:37:28 Are DMT Entities Real, Or Just Icons?1:46:35 Nine Conjectures To Rebuild All Of Physics1:49:29 UFOs At Mach 401:50:19 Neuroscience As Headset Engineering1:57:13 Hacking The Source Code Of Reality2:04:28 AI Is "Dumber Than Cucumbers".....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinMichael Masters is the biological anthropologist who thinks the grey aliens might be us. A professor at Montana Technological University, he studies how the human skull, face and eyes evolved over six million years, and has excavated at a 3.5-million-year-old hominin site in South Africa. His extratempestrial hypothesis argues that the beings described in UFO encounters are our own descendants, travelling back in time to study their evolutionary past. He says it's falsifiable, just not in his lifetime.Expect to learn:- The Brazilian Farmer: the 1950s abduction that ended in sex with a near-human woman- The Earlier Cases: the abduction reports that predate Betty and Barney Hill- Brain Up, Face Back: why six million years of skull evolution point towards the greys- The Gamete Problem: why our descendants might come back for our sperm and eggs- Falsifiable By Time: why he'll be "long dead" before anyone knows if he's rightSPONSORSGet Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderGS EPISODES MENTIONEDAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDARick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscGUEST LINKSMontana Tech Faculty Profile: https://mtech.edu/arts-sciences/faculty/michael-masters/index.htmlX: https://x.com/MorphoTimeWebsite: https://idflyobj.com/Identified Flying Objects (2019): https://www.leighbureau.com/books/identified-flying-objectsThe Extratempestrial Model (2022): https://www.leighbureau.com/books/the-extratempestrial-modelLomas, Case & Masters (2024), The Cryptoterrestrial Hypothesis: https://doi.org/10.29202/phil-cosm/33/3LISTEN ONYouTube - https://youtu.be/FRFT3PeiWwkApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:26 The Skull Scientist Who Studies UFOs0:03:46 "They Could Be Us From The Future"0:07:21 The Book On The Shelf That Started It All0:09:10 Whitley Strieber And Communion0:10:49 Abductees Who Never Told Their Own Families0:17:13 The Archetypal Abduction Story0:19:38 The Nimitz: 80,000ft In Under Two Seconds0:20:37 The Farmer Who Had Sex With An Alien0:22:22 "I Just Floated Right Through The Ceiling"0:24:06 Did Sci-Fi Invent Alien Abductions?0:29:15 DMT Entities, Machine Elves And UFOs0:37:32 The 2017 Story That Broke UFOs Open0:42:08 "The Disc-Shaped Craft Are The Time Machine"0:44:39 Why The Greys Are Built Like Hominins0:47:26 Can You Really Fast-Forward Evolution?0:49:30 Brain Up, Face Back: 6 Million Years Of Skulls0:56:04 Are We Just Projecting Human Faces?1:00:13 How Far In The Future Are They From?1:03:23 Why Would We Evolve To Look Like That?1:06:51 Falling Sperm Counts And The Gamete Mystery1:15:01 How Do You Falsify Time-Travelling Aliens?1:22:27 Teaching A University Class On UFOs1:30:13 Is The US Government Hiding Something Huge?1:32:40 Keeping UFOs Quiet Through Grad School.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinJanice Holden is a near-death-experience researcher who designed the first hospital experiment to catch consciousness outside the body, edits the Journal of Near-Death Studies and spent 31 years on the University of North Texas faculty. For nearly 40 years she has tested one claim: that patients whose hearts have stopped can see the room from above. Surgeons have corroborated some of those details. No controlled study has caught one yet.Expect to learn:- The Leg In The Yellow Bag: an anaesthetised patient described an amputation in the next operating room- The Post-it Notes: a heart patient saw a detail only his surgeon would know- The Hidden-Target Experiment: pictures hidden near hospital ceilings, visible only from above- The Life Review: reliving every moment of your life as the people you affected- DMT Vs Near-Death: why the brain may interpret reality rather than create itSPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDRick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscAnil Seth - No. 1 Consciousness Expert: Optical Illusions that Prove Reality is a Lie, Emotions, Books and AI!: https://youtu.be/lOSA06K0l1oKarl Friston - Meet The Neuroscientist Who Created The Best Universal Theory Of Brain Function: https://youtu.be/R-IZOFs4qmYMarjorie Woollacott - Neuroscientist: "Your Brain Doesn't Create Consciousness" — NDEs, Telepathy and Terminal Lucidity: https://youtu.be/mDWtmfmIUHAGUEST LINKSWebsite: https://www.janholden.comThe Handbook of Near-Death Experiences: https://www.amazon.com/dp/0313358648Journal of Near-Death Studies: https://www.janholden.com/jndsIANDS: https://iands.orgArticles: https://www.janholden.com/copy-of-articlesLISTEN ONYouTube - https://youtu.be/RAXr5ZavLk4Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:15 From Doctoral Student To 40 Years Of Near-Death Research0:03:38 How Resuscitation Created The Near-Death Experience0:09:06 What Actually Happens During A Near-Death Experience0:11:03 Moving At The Speed Of Thought0:11:41 The Tunnel And The City Of Light0:13:18 The Life Review: Feeling What Everyone Else Felt0:14:55 "It's Not Your Time": Why People Come Back0:19:27 Why Near-Death Experiences Aren't Just Dreams0:21:09 The Woman Who Watched Her Own Surgery0:27:11 The Post-it Notes A Dead Patient Saw0:32:31 The Doctors Who Corroborated These Cases0:33:39 The Harvard Neurosurgeon Who Changed His Mind0:37:38 Why "False Memory" Doesn't Explain It0:40:08 The Patient Who Floated Into The CPR Training Room0:45:05 Hiding Pictures On Hospital Ceilings0:49:35 Seven Studies, No Hits Yet0:53:32 Is Humanity Ready For Proof?0:58:08 DMT Vs Near-Death Experiences1:06:35 Does The Brain Create Reality Or Interpret It?1:10:27 Consciousness Before Birth And After Death1:14:47 Why Don't We See This All The Time?1:17:30 Karma And The Afterlife In Southeast Asia.....Email for sponsorship enquiries: [email protected]

🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinCarlos Sonnenschein is Professor of Integrative Physiology and Pathobiology at Tufts University School of Medicine. With Ana Soto, he developed the tissue organisation field theory of cancer: the idea that a tumour begins not in a rogue cell, but in the breakdown of the tissue around it. For fifty years he has argued that cancer research has been looking one level too low. Here he explains why the mutations we find in tumours may be the wreckage, not the cause.Expect to learn:- The default state: why every cell's natural tendency is to proliferate- Growth factors: why he argued they don't exist, and why people laughed- Mutations without cancer: why he says no gene has been shown to cause a cancer- Targeted therapy: why he believes the target was never really there- Cellular agency: how life, proliferation and motility fit togetherSPONSORSGet Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderGS EPISODES MENTIONEDMichael Levin - Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyMGUEST LINKSGoogle Scholar: https://scholar.google.com/citations?user=VmTCfroAAAAJIEA Nantes Fellow Profile: https://www.iea-nantes.fr/en/fellows/carlos-sonnenscheinBiological Purpose Project: https://www.biologicalpurpose.org/people/carlos-sonnenscheinResearchGate: https://www.researchgate.net/profile/Carlos-SonnenscheinAn Integrative Approach Toward Biology, Organisms, and Cancer (2018): https://pubmed.ncbi.nlm.nih.gov/29119499LISTEN ONYouTube - https://youtu.be/AypMhvhWwjgApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:26 From Paediatrics to Cancer Research0:05:23 The Oestrogen Paradox0:08:43 Proliferation Is the Default State of Every Cell0:12:27 Inhibitors of Inhibitors0:14:06 "Growth Factors Don't Exist"0:15:31 The Somatic Mutation Theory0:17:41 The Society of Cells and the Tissue Theory of Cancer0:21:44 Stars and Dogs: Funding a Minority View0:23:49 Teaching Cancer Through Genetics0:25:01 How Does Tissue Keep Cells in Check?0:26:04 Metastasis0:28:34 Prostate Cancer and Spontaneous Regression0:30:38 The Cost of Cancer Treatment0:31:49 Melanoma, UV and the Standard Model0:32:24 Mutations Without Cancer0:35:17 No Gene Causes Cancer: BRCA1, p53 and RAS0:37:00 Why Targeted Therapy Isn't Targeted0:38:03 When Treatment Causes Cancer0:40:39 What Does Genome Sequencing Tell You?0:42:24 Why Does Cancer Run in Families?0:45:41 Trauma, Healing and Tissue Robustness0:47:59 A Theory of Organisms0:50:59 What Is Life?0:52:18 Economics Is a Branch of Biology0:53:36 Cellular Agency0:58:36 Defining Life: Proliferation and Motility1:01:36 When Did Cells Become Agents?1:04:49 The Future of Cancer Research1:09:52 Final Thoughts.....Email for sponsorship enquiries: [email protected]