MDS Professional Report podcast

MDS Professional Report

MDS Foundation

This podcast series provides important up-to-the-minute information on MDS including diagnosis, treatment and clinical research.
The explosion of information on MDS forces us to seek novel, alternative ways to distribute it. Podcasts gives us an easy and popular way to communicate this information in a short time.

13 Episodes

Pathogenesis and inflammaging in MDS [MDS Professional Report]
2/1/2025
28:47
Dr. Moshe Mittelman is hosting the world-leading expert Dr. Michael Savona and they have an attractive conversation on several mechanisms involved in the pathogenesis of MDS, including the interaction between genetics, inflammation and aging.
Treatment of lower-risk MDS [MDS Professional Report]
12/15/2024
28:57
Prof. Uwe Platzbecker from Leipzig and Prof. Moshe Mittelman from Tel-Aviv in an interesting conversation on the various available therapeutic modalities for patients with lower-risk MDS.
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Treatment for Higher-risk MDS [MDS Professional Report]
12/1/2024
28:49
Prof. Nicolaus Kröger from Hamburg and Prof. Moshe Mittelman from Tel-Aviv, in a stimulating conversation on the various therapeutic modalities, including hematopoietic transplantation, in patients with higher-risk MDS.
Update on Higher-Risk MDS - Lessons from 2023 ASH [MDS Professional Report]
5/27/2024
21:49
Dr. Nicolaos Papadantonakis from Emory Atlanta and Dr. Moshe Mittelman from Tel-Aviv, describe several updated abstracts from 2023 ASH with a special focus on Higher-risk MDs, and providing their take home messages.
New trials to address the anemia of lower-risk MDS [MDS Professional Report]
3/27/2024
27:58
Drs Nikolaos Papadantonakis of Emory, Atlanta, US, and Moshe Mittelman, Tel-Aviv, Israel, discuss trials presented in American Society of Hematology (ASH) 2023 meeting. They provide some data on luspatercept, imetelstat, roxodustat and Ker-050.
Transfusions and quality of life [MDS Professional Report]
5/1/2023
21:49
Prof. Rena Buckstein from Toronto, and Prof. Moshe Mittelman from Tel-Aviv discuss issues related to RBC transfusions, the hemoglobin threshold for transfusion and related quality of life issues.
Bone marrow failure disorders in childhood [MDS Professional Report]
12/5/2022
22:31
Prof. Akiko Shimamura of Harvard Medical School, Boston, a world known expert of pediatric hematology discusses with Prof. Guillermo Sanz ,of Valencia and Prof. Moshe Mittelman, of Tel Aviv, the various aspects of bone marrow failure including childhood MDS, the differences of this medical problem between adults and children, the unique approach to sick kids and the increasing number of promising therapeutic options.
The role of genetics in MDS management [MDS Professional Report]
9/28/2022
22:02
Drs. Rafael Bejar (San Diego) and Moshe Mittelman (Tel Aviv) discuss several papers highlighting the role of genetics in MDS diagnosis, follow up and prediction of treatment. They also discuss the role of the newly approved luspatercept in the treatment of anemic transfusion-dependent patients with lower-risk MDS
MDS in ASH 2021 – Are we already in the molecular era? [MDS Professional Report]
2/6/2022
36:12
Drs. Moshe Mittelman, of The Tel Aviv Sourasky Medical Center, and DroritMerkel, of the Sheba Medical Center, both from Tel Aviv University, Israel,discuss several important presentations from the recent 2021 ASH meeting.They focus on the new IPSS-M classification, discuss the approach to theMDS patient who is currently defined by IPSS/R as belonging to the /lower-risk group but in fact the disease behaves like a higher-risk. Finally, theydiscuss issues regarding the treatment of patients with HR-MDS: What can beadded to hypomethylating agents ? Targeted therapy with IDH1/2 inhibitionand more…
Do immune check inhibitors have a role in the treatment of higher-risk MDS? [MDS Professional Report]
9/22/2021
23:44
Chien Aza – Pembro - BJHThe combination of azacitidine and pembrolizumab may be a potential effective regimen for patients with higher-risk MDS and may lead to the introduction of an important class of medications into MDS practiceNazha, Prog model – JCOA personalized prediction model, based on clinical and genomic data, outperformed established prognostic models in MDS. The use of digital tools allow us to manage big data taken from large numbers of patients and include them in the newly developed diagnostic and prognostic models. Keundgen , t-MDS- Leukemia Therapy-related MDS should be classified as a separate entity distinct from other WHO-classified t-myeloid neoplasms, which would enhance treatment decisions and facilitate the inclusion of t-MDS patients into clinical studies. Strapatsas, PLT, Ann Hem The authors re-confirm the importance of PLT count as a prognostic factor in MDS, both at presentation and during the disease course. Bleeding is a leading (3rd ) cause of death in these patients.

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