The MicrobiomeResearchX (MRX) Podcast

Our guest today is Lina Yao at Harvard Medical School who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids.”  Details about the prize-winning essaywww.science.org/doi/10.1126/science.adq2341Lina Yao Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids.Science385,37-37(2024).DOI:10.1126/science.adq2341

Our guest today is Brittany Needham at Indiana University who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Exposed wires: A microbial metabolite influences myelination in the brain.”  Details about the prize-winning essaywww.science.org/doi/10.1126/science.adq2344Brittany Needham Exposed wires: A microbial metabolite influences myelination in the brain. Science 385,37-37(2024). DOI:10.1126/science.adq2344

Our guest today is Kazuki Nagashima at Stanford University, who is the grand prize winner of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented.”  Details about the prize-winning essaywww.science.org/doi/10.1126/science.adq2335Kazuki NagashimaBlockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented. Science385,36-37(2024).DOI:10.1126/science.adq2335

Our guest today is Christoph A. Thaiss the Microbiology Department of the Perelman School of Medicine at the University of Pennsylvania, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "A microbiome exercise: gut-brain connections drive the motivation to work out.”  Details about the prize-winning essayhttps://www.science.org/doi/10.1126/science.adi6329Essay: A microbiome exerciseScience, 381, 6653, p. 38, 2023. DOI: 10.1126/science.adi6329Related research L. Dohnalová et al A microbiome-dependent gut-brain pathway regulates motivation for exercise. Nature, 612(7941):739-747, 2022. DOI: 10.1038/s41586-022-05525-z. E

Our guest today is Christopher Stewart of the Translational and Clinical Research Institute at Newcastle University, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Diet-microbe-host interaction in early life: breastmilk bioactives are important to infant microbiome.”  Details about the prize-winning essayhttps://www.science.org/doi/10.1126/science.adi6318Essay: Diet-microbe-host interaction in early lifeScience, 381, 6653, p. 38, (2023)DOI: 10.1126/science.adi6318Related research C. J Stewart et al, Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature 562 (7728): 583-588, (2018). DOI: 10.1038/s41586-018-0617-x. 

Our guest today is Sara Clasen of the Max Planck Institute for Biology in Tübingen, Germany, who is the recipient of the 2023 NOSTER & Science Microbiome Grand Prize for her essay entitled, “The sound of silence”. Details about the prize-winning essayhttps://www.science.org/content/page/2023-noster-science-prize-winnersEssay: The sound of silenceScience, 381, 6653, pp. 37-38,  2023DOI: 10.1126/science.adi6265Related research Clasen SJ, Bell MEW, Borbón A, Lee DH, Henseler ZM, de la Cuesta-Zuluaga J, Parys K, Zou J, Wang Y, Altmannova V, Youngblut ND, Weir JR, Gewirtz AT, Belkhadir Y, Ley RE. Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor-5. Sci Immunol. 2023 Jan 6;8(79):eabq7001.doi: 10.1126/sciimmunol.abq7001

Our guest today is Jennifer Hampton Hill, University of Utah is the recipient of the 2022 NOSTER & Science Microbiome Grand Prize for her work that “revealed that the resident microbiome is a promising source of previously undiscovered modulators of host β cells.”Links to details about the prize-winning essayhttps://www.science.org/content/page/2022-noster-science-prize-winnersEssay: From bugs to β cellsSCIENCE, 7 Jul 2022, Vol 377, Issue 6602, pp. 164-165 DOI: 10.1126/science.abq6051https://www.science.org/doi/10.1126/science.abq6051Latest research Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney, Elena S. Wall, Philip Jahl, Rickesha Bell, Karen Kallio, Daniel Derrick, L. Charles Murtaugh, Raghuveer Parthasarathy, S. James Remington, June L. Round, Karen Guillemin BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass Cell Metabolism, 34, pp. 1779-1791.e9, (2022)https://doi.org/10.1016/j.cmet.2022.09.001. https://www.sciencedirect.com/science/article/pii/S1550413122003916 Media Coverage U OF U HEALTH POSTDOCTORAL FELLOW EARNS PRESTIGIOUS NOSTER AND SCIENCE MICROBIOME PRIZEhttps://uofuhealth.utah.edu/newsroom/news/2022/07/hill-noster-science-prize Jumpstarting insulin production with microbial diversity wins NOSTER & Science Microbiome Prizehttps://www.eurekalert.org/news-releases/957641 MRX websitehttps://noster-mrx.net/2022 NOSTER & Science Microbiome Prize: Noster Inc and AAAS announce the grand winner and finalists of the 2022 NOSTER & Science Microbiome Prizehttps://noster-mrx.net/post/700075484746317824/news-and-events 

Our guest today is Erez Baruch, who recently started an internal medicine residency in a research (Physician-Scientist) track to medical oncology. Internal medicine training is conducted at the McGovern Medical School in Houston, Texas.Erez is a finalist of the 2021 NOSTER & Science Microbiome Prize for his essay, "Microbiota modulation to fight cancer”, based on his research on “mechanisms of immunotherapy resistance and toxicity, modulation of the gut microbiota, and interaction between innate and adaptive immune cells”. Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.MRX https://noster-mrx.net/Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-diseaseEssay by Erez Baruchhttps://www.science.org/doi/full/10.1126/science.abi9360

Our guest today is Maria Zimmermann-Kogadeeva, who started her lab in the Genome Biology Unit at EMBL Heidelberg in 2021.Maria is a finalist of the 2021 NOSTER & Science Microbiome Prize for her essay, "Quantifying host-microbiota interactions” based on her research on the adaptation and consequences of microbes to their surroundings in hosts.Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.https://noster-mrx.net/Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-diseaseEssay by Maria Zimmermann-Kogadeevahttps://www.science.org/doi/full/10.1126/science.abi9357

Our guest today is Eran Blacher, who is currently a senior postdoctoral fellow at Stanford School of Medicine studying the immune system-gut-brain axis in ageing and neurological disorders. Eran is the Grand Prize winner of the 2021 NOSTER & Science Microbiome Prize for his essay, “Can microbes combat neurodegeneration?” based on his research on the relationship between the microbiome and neurodegenerative diseases such as Alzheimer's disease.Links to details about the prize-winning essay are available on the MicrobiomeResearchX (MRX) website and related AAAS sites. MRX website https://noster-mrx.net/Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-diseaseEssay by Eran Blacherhttps://www.science.org/doi/full/10.1126/science.abi9353