Going Deep on Finding Much Better Treatments for Depression

After much back and forth with you all on Facebook, I came up with my most important go-to items — the things that get me through the day — and, more importantly, the ideas that ground me on the epic journey of motherhood. (Previously aired)

Dr. Leanne Williams is determined to spare people the suffering she’s endured. Her partner of many years died by suicide after fighting a depression that resisted all treatment. She has devoted her life as a scientist at Stanford to applying the principles and tactics of precision medicine to depression, which she has categorized into sub-types (much as was done with cancer decades ago). Joining me in this conversation are Dr BJ Miller, a friend and previous guest who works as a palliative care doc and lost his sister to suicide, as well as Emmy-winning comedian W. Kamau Bell, also a friend and previous guest, who brings his usual good will and insight to the conversation. This episode contains a detailed discussion of suicide. If you are experiencing a mental health crisis, please dial 988 to reach the Suicide & Crisis Lifeline. Thanks to PBS for supporting this series. You can watch any of these episodes ay time at PBS.org/kelly. Feedback welcome at [email protected].

Nancy Brown, a military spouse of 19 years, wrote this loving tribute for her two best deployment buddies. It honors the way the three friends formed one great big family while living through several deployments in Eastern North Carolina. Three women, no husbands and nine children all dressed in each other's hand-me-downs. On paper, they were more different than alike but maybe that's a more accurate description of a family after all. (Previously aired)

I’ve done it again. I accidentally saw the world through my own lens and forgot all the other ways life unfolds for the people who listen to this show. Thanks to a listener named Micah Boyett who sent a lovely piece of unmistakable feedback — coated in genuine kindness — I learned the lesson again. We really respect our listeners and find your emails invaluable as we steer this ship we’ve built. Write any time. [email protected]. We read every one. Micah’s book is: Blessed Are the Rest of Us: How Limits and Longing Make Us Whole

How much can we blame DNA for our depression and anxiety? Is something about our mental health pre-written into our genetic code? How much trauma carries over from one generation to the next? How should we think about epi-genetics? These were 4 of the 20 questions I brought to Dr. Francis Collins, the guy who let the team that mapped the human genome. There’s two things I want to say about this episode: I learned so much just studying for the interview and every minute I spent with Francis Collins was a total joy. He is a very special person — direct, deeply informed (maybe moreso on this topic than anyone else on Earth) and delightful. I am so excited to put his guy in your ear — a happy, loving man filled with purpose and eager to share what he knows (and doesn’t) for the greater good. And he laughs easily and a lot. So, I was getting hits of my dad the whole time. A heavenly experience that comes through in every minute of the conversation. Enjoy. Thanks to PBS stations across the country for supporting Tell Me More. You can watch an edited video version of this conversation anytime at PBS.org/kelly.

Writer Courtney Martin wrote this loving, humorous tribute to her mother for her 75th birthday. Along with detailing some of her mom’s quirks that used to drive her crazy (but which at age 43 she now appreciates), Courtney also lovingly describes her many incredible qualities. (Previously aired)

When my girls were young, I must have told them a hundred times: you get what you give. I believe it like I believe the sun will rise tomorrow. Chris Anderson, the genius do-gooder behind TED, believes it too. And with good reason. He’s seen generous giving pay off in big ways — giving his brand to TEDx conferences around the world, giving away TED speeches to anyone who wanted them online, giving attention, support and contributions to the most focused, devoted, strategic efforts on the planet. This is an episode for anyone looking for inspiration. Chris’ new book is Infectious Generosity: The Ultimate Idea Worth Spreading

Here’s why I had to sit with Dr. Dima Amso, who teaches and runs a lab that studies developmental cognition at Columbia: in a sea of hyperbole, she offers the voice of sanity and moderation, clarifying basic ideas like “good enough parenting.” For anyone who wonders how well-being is affected by our earliest childhood environments and relationships, this is the conversation for you. Please share widely with everyone who is feeling trapped by their personal history, as imperfect parents or as grown children of imperfect parents. Thanks to PBS stations across the country for supporting Tell Me More. You can watch an edited video version of this conversation anytime at PBS.org/kelly.

Michelle Hurst celebrates her husband and their marriage on the occasion of their 20th Anniversary. From 23 year-old newlyweds finding their way in the world to 43 year-old’s who have shared a puppy, kids, a mortgage and decades of meaningful memories - they have navigated it all together. (Previously aired)

There is a lot to know about what makes love last. People like John Gottman and Helen Fisher have been studying sex, love and connection for decades. Here’s a few excellent ideas to hold on to as you live out the day to day of your core relationships. Very good episode to share with your partner. Will start a valuable conversation! (Previously aired.) Kelly mentions that our episode with Dr. Helen Fisher will air next week, which is not actually the case as this is a replay BUT you can listen to that episode with the incredible Dr. Fisher HERE.