Hammer Factor Episode 79 – ‘Toscano Claps Back, Hipgrave Speaks, and Weld Goes Kayaking’

Get your Whitewater Journal HERE In our last episode of 2020, we are joined by Antoinette Lee Toscano to discuss Whitewater TV and her 'clapback' of a previous episode of The Hammer Factor. From there we bring on Chris Hipgrave to get the scoop on whitewater boat designs past and future. Next Grace gets roasted for being nervous about the Coronavirus Vaccine and of course we shut down with rants and raves. Thank you for listening and enjoy. Toscano Clapback on Whitewater TV: https://xotv.me/channels/359-whitewatertv/vod_videos/5891-bonus-episode-hammer-factor-plus-meme-boof-clapback Email From Allen Roberts: 'Hey Hammer Factor,I'm an infectious disease epidemiologist and long time paddler. I heard some misconceptions about the Covid mRNA vaccines during your last episode. I want to help clear some of these up. This isn't "hate mail" and I'm not calling anyone stupid or ignorant. Skepticism is healthy when it comes to any medical interventions that haven't been rigorously tested. And our current administration's attacks on health experts at the FDA, CDC, and NIH have only increased public mistrust. It's completely understandable to be concerned.However, the evidence thus far for both efficacy and safety is looking really good for the Pfizer and Moderna vaccines, which are the two mRNA vaccines that have results from rigorous testing. Here are a few common questions and misconceptions, many of which I heard on the podcast. I hope some of this information will be useful if you decide to keep talking about the Covid vaccine on the podcast or just in conversations with friends and family.Also, the CDC has a nice summary about mRNA vaccines here:https://www.cdc.gov/vaccines/covid-19/hcp/mrna-vaccine-basics.htmlThanks for making the Hammer Factor happen - it's great company when I'm driving to the river solo in these quarantine days.Allen RobertsSeattle, WAPS: I don't work for any pharma company in case you think Pfizer executives are paying me to write into Hammer Factor (although that sounds like the start of a good conspiracy theory!). My only interest is to avert deaths and get through this pandemic as quickly as possible. Those of us who work in a hospital setting see how bad this disease can be, both for those who are sick and for the families who aren't allowed to visit them as they die alone in the hospital. And even though most paddlers may be at low risk for severe illness from Covid, vaccination is the fastest way for us to get back to huge crowds at the Green Race and cramped van shuttles without worrying about spreading the infection.Are the Pfizer and Moderna mRNA vaccines "self-replicating"?Is this "gene therapy in a needle"? Not at all. This vaccine is NOT modifying your genes, which would require changing your cells' DNA. mRNA is the transcript that all of your cells use to make proteins. In this case, your cells are being provided a transcript to make a specific protein on the SARS-CoV-2 virus called the spike protein. This is the protein that your immune system mounts a response to. The mRNA in the Pfizer and Moderna vaccines is not "self-replicating". Your cells take up the mRNA transcript, make the spike protein, and the mRNA gets degraded. The coronavirus itself is self-replicating - so if you are worried about self-replicating genetic material infecting your cells, you're describing a virus, not a vaccine, and you should be worrying about getting Covid, not about getting vaccinated.There are self-amplifying mRNA vaccines (called sa-mRNA) that are in development, which is maybe where you heard this. This type of vaccine also includes mRNA to produce the viral polymerase, which can replicate the mRNA transcript for the spike protein.There is good reason to try this, since you could give much lower initial doses of the mRNA, but even this isn't "gene therapy". But these vaccines will have to go through rigorous testing before they could be approved.Have mRNA vaccines been tried before?