Keto Diet and Heart Disease: What New Research Reveals About Cardiac Risk with Dr. Bret Scher

In this episode, PhD researcher and fourth-year medical student Nick Norwitz returns to Metabolic Mind to discuss his recently published case series featuring ten individuals who have successfully managed their Inflammatory Bowel Disease (IBD) using a carnivore ketogenic diet. This promising approach is challenging conventional dietary norms, particularly when it comes to managing chronic inflammatory conditions. Nick delves into why this dietary intervention may offer significant therapeutic benefits for those suffering from IBD. We also explore the broader implications of how we interpret dietary studies and the impact of IBD on mental health. Join us as we examine this hopeful new frontier in metabolic health and what it could mean for those battling severe IBD symptoms. *Featured Paper* _Case report: Carnivore–ketogenic diet for the treatment of inflammatory bowel disease: a case series of 10 patients_ https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1467475/full *Experts Featured* Nick Norwitz, PhD X: @nicknorwitz https://www.linkedin.com/in/nicknorwitz/ https://www.youtube.com/@nicknorwitzPhD https://staycuriousmetabolism.substack.com/ Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#IBD#Carnivore#InflammatoryBowelDisease

In this interview with Dr. Bret Scher, Dr. Mark Horowitz, a leading clinician and researcher in anti-depressant withdrawal and de-prescribing, delves into the complex world of de-prescribing anti-depressants. Dr. Horowitz shares his personal journey with antidepressant withdrawal, which led him to dedicate his career to understanding safe tapering practices. He discusses the challenges that patients face when coming off medications, the withdrawal effects often mistaken for relapses, and how the current psychiatric guidelines may fall short in helping people safely taper. Dr. Horowitz emphasizes the importance of individualized tapering plans and the need for slower, more gradual reductions in medication, challenging the traditional approach of quick tapers over a few weeks. *Key Topics Covered* • The difference between withdrawal symptoms and relapse • The effects of long-term antidepressant use • Dr. Horowitz’s personal experience with tapering off Lexapro • The role of clinicians and peer support in the de-prescribing process *Experts Featured* Dr. Mark Horowitz X: @markhoro https://markhorowitz.org/ Resources: Safe tapering resources: https://www.outro.com/ _The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs (The Maudsley Prescribing Guidelines Series)_ https://www.amazon.com/Maudsley-Guidelines-prescribing-Prescribing/dp/111982298X Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#PsychiatricMedication#KetogenicTherapy #Tapering#Deprescribing

In this insightful interview, PhD researcher Isabella Cooper dives deep into the science of ketosis and its impact on health. She discusses how it's not just about maintaining high levels of ketones but also about the quality and source of those ketones. Isabella highlights the importance of avoiding unhealthy fats and proteins like soybean oil, canola oil, and pea protein isolate while following a ketogenic diet. Discover the latest research findings on cycling in and out of ketosis and how it can influence your overall health. Learn about the molecular components that truly matter when optimizing your metabolic state and achieving sustainable health outcomes. Tune in to explore the fascinating world of metabolic health with Dr. Isabella Cooper and uncover practical tips for enhancing your ketogenic journey! *Experts Featured* Isabella Cooper, PhD University of Westminster https://www.foreveryounggroup.com/ https://www.facebook.com/bellamitochondria X: @I_mitochondria *Related Papers* _Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females_ https://www.mdpi.com/1422-0067/24/21/15621 _Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females_ https://www.mdpi.com/2227-9059/12/7/1553 *Resources* Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Keto#Longevity

Does eating a very low carbohydrate or ketogenic diet increase the risk of heart disease? Many healthcare practitioners might say yes, but recent evidence suggests otherwise. Contrary to popular belief, a ketogenic diet does not automatically increase cardiac risk. This video explores a new study that supports this notion, challenging misconceptions that may prevent people from using ketogenic therapy to treat conditions like diabetes, depression, bipolar disorder, and other brain-based disorders. Join us in this critical discussion and share this video with your healthcare provider to help spread awareness about the true effects of ketogenic diets on heart health. *Related Videos* https://youtu.be/jybPe48bGtY https://youtu.be/cXwpYDWS0RE *Papers Mentioned* _Impact of very low carbohydrate ketogenic diets on cardiovascular risk factors among patients with type 2 diabetes; GRADE-assessed systematic review and meta-analysis of clinical trials_ https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-024-00824-w _Effect of carbohydrate-restricted dietary interventions on LDL particle size and number in adults in the context of weight loss or weight maintenance: a systematic review and meta-analysis_ https://www.sciencedirect.com/science/article/pii/S0002916522004749 _Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study_ https://pubmed.ncbi.nlm.nih.gov/29712560/ _Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial_ https://www.sciencedirect.com/science/article/pii/S0165178124001513 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#HeartHealth#HeartDisease#Keto

In this interview, Dave Feldman, citizen scientist and founder of the Citizen Science Foundation, and Nick Norwitz, Oxford PhD and Harvard medical student, discuss their latest study, which challenges the traditional view of LDL cholesterol and its relationship to heart disease risk and metabolic health. Their research focuses on lean mass hyper-responders (LMHRs)—lean, metabolically healthy individuals on a low-carb, high-fat diet, also known as a ketogenic diet. Their findings suggest that LDL cholesterol levels may not contribute to plaque buildup in these individuals as is commonly believed in the general population. They also delve into the role of coronary CT angiograms as a powerful tool for more accurately diagnosing heart health and evaluating cardiovascular risk. This study provides new insights into the intersection of cholesterol, heart disease, and metabolic health, offering fresh perspectives on how we should rethink diet, cholesterol management, and long-term health outcomes. Watch as they break down the intersection of cholesterol levels, heart disease, and metabolic health, offering fresh perspectives on assessing cardiovascular risk in modern medicine and calling for further research. Don't miss this enlightening discussion that could change how we view diet, cholesterol, and long-term health outcomes! *Featured In This Video* Dave Feldman X: @realDaveFeldman LinkedIn: https://www.linkedin.com/in/dave-feldman/ https://citizensciencefoundation.org/ Nick Norwitz, PhD X: @nicknorwitz https://www.linkedin.com/in/nicknorwitz/ *Related Papers* _Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype_ https://pubmed.ncbi.nlm.nih.gov/35106434/ _Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial_ https://www.jacc.org/doi/10.1016/j.jacadv.2024.101109 _Carbohydrate restriction-induced elevations in LDL-cholesterol and atherosclerosis: The KETO Trial_ https://www.metabolismjournal.com/article/S0026-0495(24)00080-5/abstract *Related Videos* https://youtu.be/cXwpYDWS0RE Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#Keto#KetogenicTherapy #MetabolicHealth#LDL#HeartHealth

In this powerful interview, Lauren Kennedy West shares her deeply personal journey with schizoaffective disorder and how traditional medical treatments fell short in addressing the root causes of her struggles. Lauren opens up about her discovery of metabolic therapies—focusing on diet, exercise, and sleep—which have played a crucial role in her path to wellness. Despite years of living with a challenging mental illness, Lauren found that these therapies offered a way to not just survive but truly thrive. In this interview, she discusses the gaps in conventional mental health treatment, the transformative impact of metabolic approaches, and how taking control of these often-overlooked aspects of health has allowed her to regain her life. Whether you’re dealing with similar challenges or are simply curious about alternative mental health treatments, Lauren’s story offers hope and inspiration. Join us as we explore the intersection of mental health and metabolic therapies in this compelling conversation. 🔗 Watch to learn more about Lauren’s experience and the potential of metabolic therapies in treating mental illness. *Key Topics Covered* • The limitations of traditional psychiatric treatments • The role of diet, exercise, and sleep in managing mental health • How metabolic therapies helped Lauren achieve remission Don’t forget to like, comment, and subscribe for more content on mental health, metabolic therapies, and personal wellness journeys. *People Featured in This Video* Lauren Kennedy West Creator, Living Well with Schizophrenia YouTube Channel: https://www.youtube.com/@LivingWellwithSchizophrenia Twitter/X: @LWSchizophrenia Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#SchizoaffectiveDisorder#MentalHealth#LivingWellWithSchizophrenia

Are you following a ketogenic diet or using ketogenic therapy to manage depression, bipolar disorder, schizophrenia, or other brain-based disorders? If so, you've probably heard conflicting advice about protein intake—how much is too much? In this video, Dr. Bret Scher explains how to determine the right amount of protein for your unique needs. Whether you're concerned about maintaining ketosis or just want to optimize your health, this video breaks down the science in an easy-to-understand way. *Tune in to learn* •The importance of protein on a ketogenic diet •How to measure and adjust your protein intake •Common myths and misconceptions about protein and ketosis Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Resources* Metabolic Mind’s Familes & Peers page: https://www.metabolicmind.org/families-and-peers Protein Range Chart https://www.dietdoctor.com/wp-content/uploads/2019/11/CME-Target-protein-ranges.pdf Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Protein

Dr. Mariela Glandt is a renowned endocrinologist, ketogenic therapy expert, and CEO and Co-Founder of OwnaHealth. In this interview, Dr. Glandt shares her groundbreaking work using the OwnaHealth app to treat metabolic dysfunction, type 2 diabetes, and pre-diabetes among a Medicaid population in the South Bronx. This inspiring pilot demonstrates that health improvements can transcend socioeconomic boundaries, offering hope and tangible results to underserved communities. Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Key Highlights* • The potential of ketogenic therapy for managing chronic diseases • The affordability of a ketogenic diet • Success stories from the South Bronx • The role of the OwnaHealth app in patient treatment and monitoring *Related Article* _For Richer, for Poorer: Low-Carb Diets Work for All Incomes_ by Nina Teicholz, PhD https://www.medscape.com/viewarticle/richer-poorer-low-carb-diets-work-all-incomes-2024a1000cw5?form=fpf *Experts in this video* Dr. Mariela Glandt https://www.glandt.co.il/en/home X: @DrMarielaGlandt LinkedIn: https://www.linkedin.com/in/mariela-glandt-md-6137914/ OwnaHealth https://www.owna.health/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Diabetes#LowCarbDiet

In this interview, Dr. Bret Scher speaks with Dr. Elena Gross, a neuroscientist and chronic migraine sufferer turned researcher, who shares her compelling journey and innovative approach to managing migraines through metabolic therapies. Dr. Gross discusses the critical role metabolism plays in neuropsychiatric diseases and how understanding this connection has driven her academic and professional pursuits. *Key Highlights* • Personal Journey: Dr. Elena Gross' battle with chronic migraines led her to pursue a PhD in neuroscience, focusing on the root causes of migraines and how they can be addressed through nutrition, supplements, and lifestyle changes. • Metabolic Health: An in-depth discussion on how metabolic health influences brain conditions, including migraines, and the potential for metabolic interventions to offer relief. • Scientific Insights: Exploration of the metabolic processes involved in migraine development and how targeting these processes can lead to better management of the condition. • Case Studies: Dr. Gross shares her experiences with patients and the outcomes of her clinical research, including the first randomized controlled trial on exogenous ketones for migraine treatment. • Global Implications: The broader impact of metabolic therapy on managing chronic diseases and the importance of shifting medical approaches towards prevention and root cause treatment. • Micronutrient Importance: The role of micronutrients and antioxidants in supporting metabolic health and their potential to improve outcomes for those with chronic migraines. Join us for this informative conversation with Dr. Elena Gross as she delves into her decade-long experience on ketogenic therapy and its profound impact on her life and research. By the end of this video, you'll gain a deeper understanding of how metabolic health can transform migraine management and improve overall brain health. Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Experts in this video* Dr. Elena Gross https://www.drelenagross.com X: @DrElenaGross Instagram: @drelenagross LinkedIn: https://www.linkedin.com/in/dr-elena-gross-6518bb2/ Migraket: https://www.brainritual.com/ *Studies referenced* _Efficacy and safety of exogenous ketone bodies for preventive treatment of migrane: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial_ https://link.springer.com/article/10.1186/s13063-018-3120-7 _Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention_ https://www.mdpi.com/2072-6643/11/4/811 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #Research#MetabolicHealth#Migraine #MigrainRelief

In this video, Dr. Bret Scher dives into the ongoing debate: Is the Mediterranean diet or a ketogenic diet better for mental health? While both diets have shown promise in improving symptoms of depression and other psychiatric conditions, this video examines the evidence behind each and discusses their potential benefits. According to Dr. Scher, any investigation into nutritional interventions for health conditions is a step in the right direction. Diets that steer away from the Standard American Diet (SAD) by eliminating ultra-processed foods and sugar will enhance metabolic health, likely offering both physical and mental benefits. However, ketogenic therapy isn't a conventional diet; it's an impactful metabolic treatment that modifies the brain and body's energy source. It's even possible to adopt a Mediterranean keto diet. This video provides a closer examination. Key Points: ▪️Diet and Mental Health: Importance of diet in managing psychiatric symptoms. ▪️Mediterranean Diet: Evidence from interventional studies showing improved depression symptoms. ▪️Ketogenic Diet: Recent studies and patient testimonials highlighting how ketogenic therapy can put serious mental illnesses, like major depressive disorder, bipolar disorder, and schizophrenia, into complete remission. ▪️Comparison and Recommendations: Practical advice on choosing between these diets and potential next steps for patients and clinicians looking to explore dietary interventions for mental illness. ▪️Future Directions: Ongoing research and the need for head-to-head trials to determine the most effective dietary approach for mental health. Watch to Learn: ▪️How the Mediterranean and ketogenic diets impact mental health. ▪️The underlying mechanisms by which ketosis may be a powerful intervention for brain health. ▪️Practical tips for implementing dietary changes to support mental well-being. If you found this video helpful, please like, subscribe, and share with anyone who might benefit. We also love hearing from you, so leave a comment below with your thoughts and experiences! Related Resources: What is the Difference between a Keto Diet and Ketogenic Therapy? - With Dr. Bret Scher: https://www.youtube.com/watch?v=4iMXUpLYLkk&t=1s What is a Good Bipolar Diet? - With Dr. Bret Scher: https://www.youtube.com/watch?v=mK2IDpHDrqU&t=2s Studies referenced: Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients https://pubmed.ncbi.nlm.nih.gov/35873236/ A randomized controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial) https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0791-y Effect of Multinutrient Supplementation and Food-Related Behavioral Activation Therapy on Prevention of Major Depressive Disorder Among Overweight or Obese Adults With Subsyndromal Depressive Symptoms: The MooDFOOD Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/30835307/ A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED) https://pubmed.ncbi.nlm.nih.gov/29215971/ The effect of a Mediterranean diet on the symptoms of depression in young males (the "AMMEND: A Mediterranean Diet in MEN with Depression" study): a randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/35441666/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy #KetoDiet#MediterraneanDiet