The BioViva Podcast

Klotho has been called the “King of anti-aging proteins.” It holds promise for Chronic Kidney Disease, Alzheimer’s, and other forms of dementia, and for mitigating inflammation.  Since it was named after Clotho, a Greek Fate (and all three Fates were women), we think it’s more appropriate to call her the queen. Either way, Klotho is royalty in regenerative medicine.  Klotho Gene Therapy    The expression of this gene results in the production of Klotho protein, which protects our vascular system (arteries and veins) from mineral deposits. Such deposits are harmful because they lead to what is known as “calcification” of our vascular system, a significant reason for death in patients with Chronic Kidney Disease or CKD. Therefore, not only is lack of the protein from this gene an early biomarker for CKD, but increased levels are a protectant against CKD.  Some benefits of therapy may include: Optimized Kidney Function Enhanced Learning & Cognitive Function Protection against cardiovascular disease   Klotho Links To Articles  The Putative Role of the Antiageing Protein Klotho in Cardiovascular and Renal Disease https://www.hindawi.com/journals/ijhy/2012/757469/     Klotho at the Edge of Alzheimer's Disease and Senile Depression https://www.ncbi.nlm.nih.gov/pubmed/29978424     Is Klotho the Key to Treating Alzheimer’s and Other Diseases of Aging? https://www.biospace.com/article/is-klotho-the-key-to-treating-alzheimer-s-and-other-diseases-of-aging-/     One Day There May Be a Drug to Turbocharge the Brain.  https://www.nytimes.com/2019/04/02/health/klotho-brain-enhancement-dementia-alzheimers.html