Outcomes Rocket podcast

Beyond the Picnic Cooler: Redefining Organ Preservation with Dr. Xiaoxi Wei, Founder and CEO of X-Therma

15/10/2026
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Organ preservation still runs on a plastic bag, wet ice, and a picnic cooler. In this episode, Dr. Xiaoxi Wei, Founder and CEO of X-Therma, discusses extending the lifespan of organs, cells, and other living medicines. Her grandfather's death set the work in motion. She explains why the method used to carry a donated organ has barely changed in 50 years, and why a four-hour window decides which patients get matched. X-Therma's answer is a peptoid-based material modeled on nature's antifreeze proteins, designed to hold tissue at sub-zero temperatures without freezing damage. Wei also walks through the changes that occur when preservation stretches from hours to days, including broader donor matching, more room for cell and tissue therapies, and a path away from DMSO. Tune in to hear how a new class of preservation materials could turn more donated organs into transplants! Resources: Connect with and follow Dr. Xiaoxi Wei on LinkedIn. Follow X-Therma on LinkedIn and explore the X-Therma website. Contact the X-Therma team at [email protected].

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